RIMKLB (ribosomal modification protein rimK like family member B)

Gene

• Entrez ID: 57494
• Gene name: Ribosomal modification protein rimK like family member B
• Gene symbol: RIMKLB
• Synonyms: FAM80B, NAAGS, NAAGS-I
• Chromosome: 12
• Chromosome location: 12p13.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT067440	hsa-miR-8066	PAR-CLIP	22100165
MIRT441935	hsa-miR-218-5p	PAR-CLIP	22100165
MIRT441936	hsa-miR-1273e	PAR-CLIP	22100165
MIRT441937	hsa-miR-636	PAR-CLIP	22100165
MIRT441938	hsa-miR-4480	PAR-CLIP	22100165
MIRT441939	hsa-miR-3691-3p	PAR-CLIP	22100165
MIRT441940	hsa-miR-3184-3p	PAR-CLIP	22100165
MIRT446288	hsa-miR-520h	PAR-CLIP	22100165
MIRT446289	hsa-miR-520g-3p	PAR-CLIP	22100165
MIRT446290	hsa-miR-3973	PAR-CLIP	22100165
MIRT700172	hsa-miR-6818-3p	HITS-CLIP	23313552
MIRT700173	hsa-miR-6857-5p	HITS-CLIP	23313552
MIRT700174	hsa-miR-653-3p	HITS-CLIP	23313552
MIRT700175	hsa-miR-4420	HITS-CLIP	23313552
MIRT700176	hsa-miR-181b-3p	HITS-CLIP	23313552
MIRT700177	hsa-miR-181b-2-3p	HITS-CLIP	23313552
MIRT700178	hsa-miR-513b-5p	HITS-CLIP	23313552
MIRT700179	hsa-miR-593-3p	HITS-CLIP	23313552
MIRT700180	hsa-miR-6895-3p	HITS-CLIP	23313552
MIRT700181	hsa-miR-4450	HITS-CLIP	23313552
MIRT700182	hsa-miR-4758-3p	HITS-CLIP	23313552
MIRT700183	hsa-miR-5699-5p	HITS-CLIP	23313552
MIRT700184	hsa-miR-8089	HITS-CLIP	23313552
MIRT700185	hsa-miR-4700-5p	HITS-CLIP	23313552
MIRT700186	hsa-miR-4667-5p	HITS-CLIP	23313552
MIRT700187	hsa-miR-520f-5p	HITS-CLIP	23313552
MIRT700188	hsa-miR-4323	HITS-CLIP	23313552

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	ISS
GO:0005829	Component	Cytosol	TAS
GO:0006464	Process	Cellular protein modification process	IEA
GO:0008652	Process	Cellular amino acid biosynthetic process	TAS
GO:0016879	Function	Ligase activity, forming carbon-nitrogen bonds	IBA	21873635
GO:0046872	Function	Metal ion binding	IEA
GO:0072590	Function	N-acetyl-L-aspartate-L-glutamate ligase activity	IBA	21873635
GO:0072590	Function	N-acetyl-L-aspartate-L-glutamate ligase activity	ISS
GO:0072591	Function	Citrate-L-glutamate ligase activity	ISS

Other IDs

• MIM: 614054
• HGNC: 29228
• e!Ensembl: ENSG00000166532

Protein

• UniProt ID: Q9ULI2
• Protein name: Beta-citrylglutamate synthase B (EC 6.3.1.17) (N-acetyl-aspartylglutamate synthetase B) (NAAG synthetase B) (NAAGS) (EC 6.3.2.41) (Ribosomal protein S6 modification-like protein B)
• Protein function: Catalyzes the synthesis of beta-citryl-L-glutamate and N-acetyl-L-aspartyl-L-glutamate. Beta-citryl-L-glutamate is synthesized more efficiently than N-acetyl-L-aspartyl-L-glutamate.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08443	RimK	112 → 303	RimK-like ATP-grasp domain	Domain

• Sequence:

  MCSSVAAKLWFLTDRRIREDYPQKEILRALKAKCCEEELDFRAVVMDEVVLTIEQGNLGL
  RINGELITAYPQVVVVRVPTPWVQSDSDITVLRHLEKMGCRLMNRPQAILNCVNKFWTFQ
  ELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAVFLARDKHHLADL
  SHLIRHEAPYLFQKYVKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQSNCSLGGVGMMCS
  LSEQGKQLAIQVSNILGMDVCGIDLLMKDDGSFCVCEANANVGFIAFDKACNLDVAGIIA
  DYAASLLPSGRLTRRMSLLSVVSTASETSEPELGPPASTAVDNMSASSSSVDSDPESTER
  ELLTKLPGGLFNMNQLLANEIKLLVD

• Sequence length: 386