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RAC3 (Rac family small GTPase 3)
Gene
Gene SNPs Other IDs
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5881
Gene nameGene Name - the full gene name approved by the HGNC.
Rac family small GTPase 3
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
RAC3
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
17
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q25.3
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorgani
SNPsSNP information provided by dbSNP.
Gene SNPs Other IDs
SNP ID Visualize variation Clinical significance Consequence
rs1064797229 G>A Pathogenic, uncertain-significance Coding sequence variant, missense variant
rs1379395211 C>G,T Likely-pathogenic Coding sequence variant, missense variant
rs1568018697 C>T Association, pathogenic Missense variant, coding sequence variant
rs1568018920 A>T Association, pathogenic Missense variant, coding sequence variant
miRNAmiRNA information provided by mirtarbase database.
Gene SNPs Other IDs
miRTarBase ID miRNA Experiments Reference
MIRT038692 hsa-miR-30c-2-3p CLASH 23622248
MIRT718787 hsa-miR-4687-5p HITS-CLIP 19536157
MIRT718786 hsa-miR-4446-3p HITS-CLIP 19536157
MIRT718785 hsa-miR-3155a HITS-CLIP 19536157
MIRT718784 hsa-miR-3155b HITS-CLIP 19536157
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene SNPs Other IDs
GO ID Ontology Definition Evidence Reference
GO:0003924 Function GTPase activity IBA 21873635
GO:0003924 Function GTPase activity IDA 11956649
GO:0005515 Function Protein binding IPI 11956649, 21217774, 32296183
GO:0005525 Function GTP binding IBA 21873635
GO:0005829 Component Cytosol TAS
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene SNPs Other IDs
MIM
HGNC
e!Ensembl
Protein
Gene SNPs Other IDs
UniProt ID P60763
Protein name Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Protein function Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of ac
PDB 2C2H , 2G0N , 2IC5 , 2OV2 , 2QME , 6TM1
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras
5 → 178
Ras family
 Domain
Sequence
Sequence length 192
Interactions View interactions

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