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PRKAB2 (protein kinase AMP-activated non-catalytic subunit beta 2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5565
Gene nameGene Name - the full gene name approved by the HGNC.
Protein kinase AMP-activated non-catalytic subunit beta 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
PRKAB2
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
1
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q21.1
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme tha
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020411 hsa-miR-29c-3p Sequencing 20371350
MIRT027116 hsa-miR-103a-3p Sequencing 20371350
MIRT030833 hsa-miR-21-5p Microarray 18591254
MIRT031580 hsa-miR-16-5p Sequencing 20371350
MIRT047852 hsa-miR-30c-5p CLASH 23622248
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004679 Function AMP-activated protein kinase activity IDA 21399626
GO:0005515 Function Protein binding IPI 16306228, 20562859, 21516116, 21988832, 22363791, 23455922, 24722188, 25416956, 25852190, 27107012, 28514442, 29892012, 31515488, 32296183, 32814053
GO:0005634 Component Nucleus IBA 21873635
GO:0005654 Component Nucleoplasm TAS
GO:0005737 Component Cytoplasm IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID O43741
Protein name 5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2)
Protein function Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing p
PDB 2F15 , 2V8Q , 2V92 , 2V9J , 2Y8L , 2Y8Q , 2YA3 , 4CFH , 4EAI , 4EAJ , 4RER , 4REW , 6B2E , 7JHG , 7JHH , 7JIJ , 7M74
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF16561 AMPK1_CBM
77 161
Glycogen recognition site of AMP-activated protein kinase
Family
PF04739 AMPKBI
201 271
Family
Sequence
MGNTTSDRVSGERHGAKAARSEGAGGHAPGKEHKIMVGSTDDPSVFSLPDSKLPGDKEFV
SWQQDLEDSVKPTQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLPE
GEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFE
VFDALKLDSMESSETSCRD
LSSSPPGPYGQEMYAFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNH
LYALSIKDSVMVLSATHRYKKKYVTTLLYKP
I
Sequence length 272
Interactions View interactions

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