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PPP2R5E (protein phosphatase 2 regulatory subunit B'epsilon)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5529
Gene nameGene Name - the full gene name approved by the HGNC.
Protein phosphatase 2 regulatory subunit B'epsilon
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
PPP2R5E
SynonymsGene synonyms aliases
B56E, B56epsilon
ChromosomeChromosome number
14
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
14q23.2
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a co
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT006743 hsa-miR-19b-3p Luciferase reporter assay 20190740
MIRT006743 hsa-miR-19b-3p Luciferase reporter assay 20190740
MIRT051983 hsa-let-7b-5p CLASH 23622248
MIRT051753 hsa-let-7c-5p CLASH 23622248
MIRT045699 hsa-miR-125a-5p CLASH 23622248
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000159 Component Protein phosphatase type 2A complex IBA 21873635
GO:0005515 Function Protein binding IPI 15380617, 17540176, 18201571, 18782753, 19156129, 21699783, 21878643, 23555304, 24705354, 26496610, 27173435, 28330616, 30595372, 32814053
GO:0005634 Component Nucleus IBA 21873635
GO:0005737 Component Cytoplasm TAS 8703017
GO:0005829 Component Cytosol IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q16537
Protein name Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon)
Protein function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment.
PDB 8UWB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01603 B56
48 453
Protein phosphatase 2A regulatory B subunit (B56 family)
Family
Sequence
Sequence length 467
Interactions View interactions

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