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PPP1CC (protein phosphatase 1 catalytic subunit gamma)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5501
Gene nameGene Name - the full gene name approved by the HGNC.
Protein phosphatase 1 catalytic subunit gamma
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
PPP1CC
SynonymsGene synonyms aliases
PP-1G, PP1C, PPP1G
ChromosomeChromosome number
12
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q24.11
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three close
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT028665 hsa-miR-30a-5p Proteomics 18668040
MIRT050065 hsa-miR-26a-5p CLASH 23622248
MIRT050049 hsa-miR-26b-5p CLASH 23622248
MIRT049174 hsa-miR-92a-3p CLASH 23622248
MIRT046498 hsa-miR-15b-5p CLASH 23622248
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000164 Component Protein phosphatase type 1 complex IEA
GO:0000777 Component Condensed chromosome kinetochore IEA
GO:0000781 Component Chromosome, telomeric region IDA 24270157
GO:0003723 Function RNA binding HDA 22681889
GO:0004721 Function Phosphoprotein phosphatase activity TAS
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P36873
Protein name Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Protein function Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets (PubMed:17936702, PubMed:25012651). Protein phosphatase 1 (PP1) is essential for cell
PDB 1IT6 , 1JK7 , 1U32 , 2BCD , 2BDX , 4UT2 , 4UT3 , 5INB , 5J28 , 7SD0 , 8B5R
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF16891 STPPase_N
9 56
Serine-threonine protein phosphatase N-terminal domain
Family
PF00149 Metallophos
57 252
Calcineurin-like phosphoesterase
Domain
Sequence
Sequence length 323
Interactions View interactions

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