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PPARD (peroxisome proliferator activated receptor delta)

Gene

5467

Peroxisome proliferator activated receptor delta

PPARD

FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB

6p21.31

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcr

Show/Hide all(268)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049777	hsa-miR-92a-3p	CLASH	23622248
MIRT043275	hsa-miR-331-3p	CLASH	23622248
MIRT053749	hsa-miR-29b-3p	Microarray	22942087
MIRT439926	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439926	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT1251745	hsa-miR-106a	CLIP-seq
MIRT1251746	hsa-miR-106b	CLIP-seq
MIRT1251747	hsa-miR-1205	CLIP-seq
MIRT1251748	hsa-miR-1266	CLIP-seq
MIRT1251749	hsa-miR-1321	CLIP-seq
MIRT1251750	hsa-miR-148a	CLIP-seq
MIRT1251751	hsa-miR-148b	CLIP-seq
MIRT1251752	hsa-miR-152	CLIP-seq
MIRT1251753	hsa-miR-17	CLIP-seq
MIRT1251754	hsa-miR-20a	CLIP-seq
MIRT1251755	hsa-miR-20b	CLIP-seq
MIRT1251756	hsa-miR-3202	CLIP-seq
MIRT1251757	hsa-miR-34a	CLIP-seq
MIRT1251758	hsa-miR-34c-5p	CLIP-seq
MIRT1251759	hsa-miR-3609	CLIP-seq
MIRT1251760	hsa-miR-3665	CLIP-seq
MIRT1251761	hsa-miR-3689d	CLIP-seq
MIRT1251762	hsa-miR-4270	CLIP-seq
MIRT1251763	hsa-miR-4441	CLIP-seq
MIRT1251764	hsa-miR-449a	CLIP-seq
MIRT1251765	hsa-miR-449b	CLIP-seq
MIRT1251766	hsa-miR-4518	CLIP-seq
MIRT1251767	hsa-miR-4728-5p	CLIP-seq
MIRT1251768	hsa-miR-4730	CLIP-seq
MIRT1251769	hsa-miR-4739	CLIP-seq
MIRT1251770	hsa-miR-4747-5p	CLIP-seq
MIRT1251771	hsa-miR-4756-5p	CLIP-seq
MIRT1251772	hsa-miR-4796-3p	CLIP-seq
MIRT1251773	hsa-miR-486-3p	CLIP-seq
MIRT1251774	hsa-miR-512-3p	CLIP-seq
MIRT1251775	hsa-miR-519d	CLIP-seq
MIRT1251776	hsa-miR-520f	CLIP-seq
MIRT1251777	hsa-miR-548ah	CLIP-seq
MIRT1251778	hsa-miR-596	CLIP-seq
MIRT1251779	hsa-miR-657	CLIP-seq
MIRT1251780	hsa-miR-93	CLIP-seq
MIRT1251745	hsa-miR-106a	CLIP-seq
MIRT1251746	hsa-miR-106b	CLIP-seq
MIRT1251747	hsa-miR-1205	CLIP-seq
MIRT1251781	hsa-miR-1262	CLIP-seq
MIRT1251782	hsa-miR-1287	CLIP-seq
MIRT1251783	hsa-miR-1324	CLIP-seq
MIRT1251750	hsa-miR-148a	CLIP-seq
MIRT1251751	hsa-miR-148b	CLIP-seq
MIRT1251752	hsa-miR-152	CLIP-seq
MIRT1251753	hsa-miR-17	CLIP-seq
MIRT1251754	hsa-miR-20a	CLIP-seq
MIRT1251755	hsa-miR-20b	CLIP-seq
MIRT1251784	hsa-miR-2115	CLIP-seq
MIRT1251785	hsa-miR-3135b	CLIP-seq
MIRT1251786	hsa-miR-3184	CLIP-seq
MIRT1251787	hsa-miR-3194-3p	CLIP-seq
MIRT1251788	hsa-miR-3195	CLIP-seq
MIRT1251759	hsa-miR-3609	CLIP-seq
MIRT1251789	hsa-miR-3622b-5p	CLIP-seq
MIRT1251760	hsa-miR-3665	CLIP-seq
MIRT1251790	hsa-miR-423-5p	CLIP-seq
MIRT1251791	hsa-miR-4455	CLIP-seq
MIRT1251792	hsa-miR-4688	CLIP-seq
MIRT1251793	hsa-miR-4691-5p	CLIP-seq
MIRT1251794	hsa-miR-4701-3p	CLIP-seq
MIRT1251772	hsa-miR-4796-3p	CLIP-seq
MIRT1251773	hsa-miR-486-3p	CLIP-seq
MIRT1251795	hsa-miR-516a-3p	CLIP-seq
MIRT1251775	hsa-miR-519d	CLIP-seq
MIRT1251776	hsa-miR-520f	CLIP-seq
MIRT1251777	hsa-miR-548ah	CLIP-seq
MIRT1251778	hsa-miR-596	CLIP-seq
MIRT1251796	hsa-miR-609	CLIP-seq
MIRT1251779	hsa-miR-657	CLIP-seq
MIRT1251797	hsa-miR-760	CLIP-seq
MIRT1251780	hsa-miR-93	CLIP-seq
MIRT1251798	hsa-miR-1182	CLIP-seq
MIRT1251799	hsa-miR-122	CLIP-seq
MIRT1251785	hsa-miR-3135b	CLIP-seq
MIRT1251800	hsa-miR-3166	CLIP-seq
MIRT1251801	hsa-miR-3615	CLIP-seq
MIRT1251802	hsa-miR-3652	CLIP-seq
MIRT1251803	hsa-miR-3664-5p	CLIP-seq
MIRT1251804	hsa-miR-3692	CLIP-seq
MIRT1251805	hsa-miR-4430	CLIP-seq
MIRT1251806	hsa-miR-4639-3p	CLIP-seq
MIRT1251807	hsa-miR-4771	CLIP-seq
MIRT1251808	hsa-miR-498	CLIP-seq
MIRT1251809	hsa-miR-541	CLIP-seq
MIRT1251810	hsa-miR-654-5p	CLIP-seq
MIRT1251783	hsa-miR-1324	CLIP-seq
MIRT2074245	hsa-miR-4251	CLIP-seq
MIRT1251783	hsa-miR-1324	CLIP-seq
MIRT1251750	hsa-miR-148a	CLIP-seq
MIRT1251751	hsa-miR-148b	CLIP-seq
MIRT1251752	hsa-miR-152	CLIP-seq
MIRT2301234	hsa-miR-1193	CLIP-seq
MIRT2301235	hsa-miR-1207-5p	CLIP-seq
MIRT2301236	hsa-miR-1285	CLIP-seq
MIRT1251750	hsa-miR-148a	CLIP-seq
MIRT1251751	hsa-miR-148b	CLIP-seq
MIRT1251752	hsa-miR-152	CLIP-seq
MIRT2301237	hsa-miR-1909	CLIP-seq
MIRT2301238	hsa-miR-24	CLIP-seq
MIRT2301239	hsa-miR-299-3p	CLIP-seq
MIRT1251786	hsa-miR-3184	CLIP-seq
MIRT2301240	hsa-miR-3187-5p	CLIP-seq
MIRT2301241	hsa-miR-3192	CLIP-seq
MIRT2301242	hsa-miR-3607-5p	CLIP-seq
MIRT2301243	hsa-miR-3616-3p	CLIP-seq
MIRT1251790	hsa-miR-423-5p	CLIP-seq
MIRT2301244	hsa-miR-4265	CLIP-seq
MIRT1251762	hsa-miR-4270	CLIP-seq
MIRT2301245	hsa-miR-4296	CLIP-seq
MIRT2301246	hsa-miR-4300	CLIP-seq
MIRT2301247	hsa-miR-4322	CLIP-seq
MIRT2301248	hsa-miR-4417	CLIP-seq
MIRT1251763	hsa-miR-4441	CLIP-seq
MIRT1251791	hsa-miR-4455	CLIP-seq
MIRT1251792	hsa-miR-4688	CLIP-seq
MIRT2301249	hsa-miR-4763-3p	CLIP-seq
MIRT1251776	hsa-miR-520f	CLIP-seq
MIRT2301250	hsa-miR-561	CLIP-seq
MIRT1251796	hsa-miR-609	CLIP-seq
MIRT2301251	hsa-miR-612	CLIP-seq
MIRT2301252	hsa-miR-642b	CLIP-seq
MIRT2301253	hsa-miR-9	CLIP-seq
MIRT2301254	hsa-miR-920	CLIP-seq
MIRT2301235	hsa-miR-1207-5p	CLIP-seq
MIRT2301236	hsa-miR-1285	CLIP-seq
MIRT2301237	hsa-miR-1909	CLIP-seq
MIRT2301239	hsa-miR-299-3p	CLIP-seq
MIRT2301240	hsa-miR-3187-5p	CLIP-seq
MIRT2301244	hsa-miR-4265	CLIP-seq
MIRT2301245	hsa-miR-4296	CLIP-seq
MIRT2301247	hsa-miR-4322	CLIP-seq
MIRT2301248	hsa-miR-4417	CLIP-seq
MIRT2392866	hsa-miR-4704-5p	CLIP-seq
MIRT2301249	hsa-miR-4763-3p	CLIP-seq
MIRT2392867	hsa-miR-4763-5p	CLIP-seq
MIRT2301251	hsa-miR-612	CLIP-seq
MIRT2301252	hsa-miR-642b	CLIP-seq
MIRT2597830	hsa-miR-1178	CLIP-seq
MIRT1251747	hsa-miR-1205	CLIP-seq
MIRT2301235	hsa-miR-1207-5p	CLIP-seq
MIRT2597831	hsa-miR-1224-3p	CLIP-seq
MIRT2597832	hsa-miR-1229	CLIP-seq
MIRT2597833	hsa-miR-1237	CLIP-seq
MIRT2597834	hsa-miR-1248	CLIP-seq
MIRT2597835	hsa-miR-1254	CLIP-seq
MIRT1251781	hsa-miR-1262	CLIP-seq
MIRT2301236	hsa-miR-1285	CLIP-seq
MIRT2597836	hsa-miR-1286	CLIP-seq
MIRT2597837	hsa-miR-1291	CLIP-seq
MIRT2597838	hsa-miR-1294	CLIP-seq
MIRT1251783	hsa-miR-1324	CLIP-seq
MIRT2301237	hsa-miR-1909	CLIP-seq
MIRT2597839	hsa-miR-1913	CLIP-seq
MIRT1251784	hsa-miR-2115	CLIP-seq
MIRT2597840	hsa-miR-218	CLIP-seq
MIRT2301239	hsa-miR-299-3p	CLIP-seq
MIRT2597841	hsa-miR-3065-5p	CLIP-seq
MIRT2597842	hsa-miR-3116	CLIP-seq
MIRT2597843	hsa-miR-3127-5p	CLIP-seq
MIRT1251785	hsa-miR-3135b	CLIP-seq
MIRT2597844	hsa-miR-3136-3p	CLIP-seq
MIRT2597845	hsa-miR-3173-5p	CLIP-seq
MIRT2597846	hsa-miR-3176	CLIP-seq
MIRT2597847	hsa-miR-3183	CLIP-seq
MIRT1251786	hsa-miR-3184	CLIP-seq
MIRT2301240	hsa-miR-3187-5p	CLIP-seq
MIRT2301241	hsa-miR-3192	CLIP-seq
MIRT1251787	hsa-miR-3194-3p	CLIP-seq
MIRT2597848	hsa-miR-3194-5p	CLIP-seq
MIRT1251788	hsa-miR-3195	CLIP-seq
MIRT2597849	hsa-miR-320e	CLIP-seq
MIRT2597850	hsa-miR-324-3p	CLIP-seq
MIRT2597851	hsa-miR-326	CLIP-seq
MIRT2597852	hsa-miR-328	CLIP-seq
MIRT2597853	hsa-miR-330-5p	CLIP-seq
MIRT2597854	hsa-miR-339-3p	CLIP-seq
MIRT1251757	hsa-miR-34a	CLIP-seq
MIRT1251758	hsa-miR-34c-5p	CLIP-seq
MIRT2301243	hsa-miR-3616-3p	CLIP-seq
MIRT2597855	hsa-miR-3622a-3p	CLIP-seq
MIRT2597856	hsa-miR-3622b-3p	CLIP-seq
MIRT1251789	hsa-miR-3622b-5p	CLIP-seq
MIRT2597857	hsa-miR-3661	CLIP-seq
MIRT2597858	hsa-miR-3672	CLIP-seq
MIRT2597859	hsa-miR-3921	CLIP-seq
MIRT2597860	hsa-miR-3922-3p	CLIP-seq
MIRT1251790	hsa-miR-423-5p	CLIP-seq
MIRT2597861	hsa-miR-4254	CLIP-seq
MIRT2301244	hsa-miR-4265	CLIP-seq
MIRT2597862	hsa-miR-4268	CLIP-seq
MIRT2597863	hsa-miR-4287	CLIP-seq
MIRT2597864	hsa-miR-4292	CLIP-seq
MIRT2301245	hsa-miR-4296	CLIP-seq
MIRT2301246	hsa-miR-4300	CLIP-seq
MIRT2597865	hsa-miR-4308	CLIP-seq
MIRT2301247	hsa-miR-4322	CLIP-seq
MIRT2301248	hsa-miR-4417	CLIP-seq
MIRT2597866	hsa-miR-4419a	CLIP-seq
MIRT2597867	hsa-miR-4436b-3p	CLIP-seq
MIRT2597868	hsa-miR-4447	CLIP-seq
MIRT2597869	hsa-miR-4448	CLIP-seq
MIRT1251791	hsa-miR-4455	CLIP-seq
MIRT2597870	hsa-miR-4469	CLIP-seq
MIRT2597871	hsa-miR-4472	CLIP-seq
MIRT2597872	hsa-miR-4488	CLIP-seq
MIRT2597873	hsa-miR-4493	CLIP-seq
MIRT1251764	hsa-miR-449a	CLIP-seq
MIRT1251765	hsa-miR-449b	CLIP-seq
MIRT2597874	hsa-miR-4510	CLIP-seq
MIRT2597875	hsa-miR-4649-3p	CLIP-seq
MIRT2597876	hsa-miR-4650-5p	CLIP-seq
MIRT2597877	hsa-miR-4653-5p	CLIP-seq
MIRT2597878	hsa-miR-4667-3p	CLIP-seq
MIRT2597879	hsa-miR-4685-3p	CLIP-seq
MIRT1251792	hsa-miR-4688	CLIP-seq
MIRT1251793	hsa-miR-4691-5p	CLIP-seq
MIRT2597880	hsa-miR-4693-3p	CLIP-seq
MIRT2597881	hsa-miR-4697-5p	CLIP-seq
MIRT1251794	hsa-miR-4701-3p	CLIP-seq
MIRT2597882	hsa-miR-4707-5p	CLIP-seq
MIRT2597883	hsa-miR-4714-3p	CLIP-seq
MIRT2597884	hsa-miR-4716-3p	CLIP-seq
MIRT2597885	hsa-miR-4721	CLIP-seq
MIRT2597886	hsa-miR-4722-5p	CLIP-seq
MIRT2597887	hsa-miR-4723-3p	CLIP-seq
MIRT2597888	hsa-miR-4723-5p	CLIP-seq
MIRT1251767	hsa-miR-4728-5p	CLIP-seq
MIRT1251768	hsa-miR-4730	CLIP-seq
MIRT2597889	hsa-miR-4733-3p	CLIP-seq
MIRT2597890	hsa-miR-4749-3p	CLIP-seq
MIRT2301249	hsa-miR-4763-3p	CLIP-seq
MIRT2392867	hsa-miR-4763-5p	CLIP-seq
MIRT2597891	hsa-miR-4792	CLIP-seq
MIRT1251773	hsa-miR-486-3p	CLIP-seq
MIRT2597892	hsa-miR-490-3p	CLIP-seq
MIRT2597893	hsa-miR-492	CLIP-seq
MIRT2597894	hsa-miR-508-5p	CLIP-seq
MIRT1251774	hsa-miR-512-3p	CLIP-seq
MIRT1251795	hsa-miR-516a-3p	CLIP-seq
MIRT2597895	hsa-miR-539	CLIP-seq
MIRT2597896	hsa-miR-583	CLIP-seq
MIRT1251796	hsa-miR-609	CLIP-seq
MIRT2301251	hsa-miR-612	CLIP-seq
MIRT2597897	hsa-miR-619	CLIP-seq
MIRT2597898	hsa-miR-631	CLIP-seq
MIRT2597899	hsa-miR-636	CLIP-seq
MIRT2301252	hsa-miR-642b	CLIP-seq
MIRT1251797	hsa-miR-760	CLIP-seq
MIRT2597900	hsa-miR-766	CLIP-seq
MIRT2597901	hsa-miR-767-3p	CLIP-seq
MIRT2597902	hsa-miR-769-5p	CLIP-seq
MIRT2301254	hsa-miR-920	CLIP-seq
MIRT2597903	hsa-miR-942	CLIP-seq
MIRT1251799	hsa-miR-122	CLIP-seq
MIRT2688402	hsa-miR-1290	CLIP-seq
MIRT1251785	hsa-miR-3135b	CLIP-seq
MIRT1251802	hsa-miR-3652	CLIP-seq
MIRT1251805	hsa-miR-4430	CLIP-seq
MIRT2688403	hsa-miR-4654	CLIP-seq
MIRT2688404	hsa-miR-4769-5p	CLIP-seq
MIRT1251809	hsa-miR-541	CLIP-seq
MIRT1251810	hsa-miR-654-5p	CLIP-seq

Transcription factors

Show/Hide all(3)

Transcription factor	Regulation	Reference
CTNNB1	Unknown	17724465
JUN	Activation	18625220
RELA	Repression	14708613

Show/Hide all(86)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IBA	21873635
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	ISS
GO:0000785	Component	Chromatin	ISA
GO:0000785	Component	Chromatin	ISS
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001103	Function	RNA polymerase II repressing transcription factor binding	IBA	21873635
GO:0001223	Function	Transcription coactivator binding	IPI	15001550
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA	21873635
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISS
GO:0003677	Function	DNA binding	ISS
GO:0003700	Function	DNA-binding transcription factor activity	IDA	12955147, 15001550
GO:0003700	Function	DNA-binding transcription factor activity	NAS	11551955
GO:0003707	Function	Steroid hormone receptor activity	TAS	1333051
GO:0004879	Function	Nuclear receptor activity	IBA	21873635
GO:0004879	Function	Nuclear receptor activity	IDA	12955147
GO:0005515	Function	Protein binding	IPI	15722453, 23455924
GO:0005634	Component	Nucleus	NAS	11551955
GO:0005654	Component	Nucleoplasm	TAS
GO:0006006	Process	Glucose metabolic process	NAS	15793256
GO:0006029	Process	Proteoglycan metabolic process	IEA
GO:0006091	Process	Generation of precursor metabolites and energy	TAS	1333051
GO:0006357	Process	Regulation of transcription by RNA polymerase II	TAS	1333051
GO:0006367	Process	Transcription initiation from RNA polymerase II promoter	TAS
GO:0006629	Process	Lipid metabolic process	ISS
GO:0006631	Process	Fatty acid metabolic process	IBA	21873635
GO:0006635	Process	Fatty acid beta-oxidation	ISS
GO:0006635	Process	Fatty acid beta-oxidation	TAS	15192438, 15803109
GO:0006776	Process	Vitamin A metabolic process	IEA
GO:0006915	Process	Apoptotic process	IMP	12909723
GO:0007507	Process	Heart development	IEA
GO:0007566	Process	Embryo implantation	TAS	11551955
GO:0008134	Function	Transcription factor binding	IPI	26504087
GO:0008144	Function	Drug binding	IDA	10198642
GO:0008203	Process	Cholesterol metabolic process	TAS	15192438
GO:0008270	Function	Zinc ion binding	IEA
GO:0008283	Process	Cell population proliferation	ISS
GO:0008289	Function	Lipid binding	IDA	12955147
GO:0008366	Process	Axon ensheathment	ISS
GO:0008654	Process	Phospholipid biosynthetic process	IEA
GO:0009062	Process	Fatty acid catabolic process	TAS	15192438
GO:0009749	Process	Response to glucose	IEA
GO:0009755	Process	Hormone-mediated signaling pathway	IBA	21873635
GO:0010887	Process	Negative regulation of cholesterol storage	IBA	21873635
GO:0014068	Process	Positive regulation of phosphatidylinositol 3-kinase signaling	IEA
GO:0014823	Process	Response to activity	IEA
GO:0014842	Process	Regulation of skeletal muscle satellite cell proliferation	IEA
GO:0014912	Process	Negative regulation of smooth muscle cell migration	IEA
GO:0015908	Process	Fatty acid transport	ISS
GO:0019216	Process	Regulation of lipid metabolic process	IBA	21873635
GO:0030154	Process	Cell differentiation	IBA	21873635
GO:0030308	Process	Negative regulation of cell growth	IEA
GO:0030522	Process	Intracellular receptor signaling pathway	IEA
GO:0031589	Process	Cell-substrate adhesion	IEA
GO:0032966	Process	Negative regulation of collagen biosynthetic process	IEA
GO:0033189	Process	Response to vitamin A	IEA
GO:0033993	Process	Response to lipid	IBA	21873635
GO:0035774	Process	Positive regulation of insulin secretion involved in cellular response to glucose stimulus	IEA
GO:0042060	Process	Wound healing	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043401	Process	Steroid hormone mediated signaling pathway	IEA
GO:0043415	Process	Positive regulation of skeletal muscle tissue regeneration	IEA
GO:0043616	Process	Keratinocyte proliferation	IEA
GO:0045600	Process	Positive regulation of fat cell differentiation	NAS	10991946
GO:0045662	Process	Negative regulation of myoblast differentiation	IEA
GO:0045684	Process	Positive regulation of epidermis development	IEA
GO:0045892	Process	Negative regulation of transcription, DNA-templated	ISS
GO:0045893	Process	Positive regulation of transcription, DNA-templated	IDA	12955147
GO:0045923	Process	Positive regulation of fatty acid metabolic process	IBA	21873635
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA	21873635
GO:0046321	Process	Positive regulation of fatty acid oxidation	IEA
GO:0046697	Process	Decidualization	TAS	11551955
GO:0048662	Process	Negative regulation of smooth muscle cell proliferation	IEA
GO:0050680	Process	Negative regulation of epithelial cell proliferation	IEA
GO:0050728	Process	Negative regulation of inflammatory response	IBA	21873635
GO:0051059	Function	NF-kappaB binding	IEA
GO:0051546	Process	Keratinocyte migration	IEA
GO:0060612	Process	Adipose tissue development	IEA
GO:0070539	Function	Linoleic acid binding	IDA	10198642
GO:0071222	Process	Cellular response to lipopolysaccharide	IEA
GO:0071456	Process	Cellular response to hypoxia	IEA
GO:0097190	Process	Apoptotic signaling pathway	IMP	11551955
GO:1902894	Process	Negative regulation of pri-miRNA transcription by RNA polymerase II	ISS
GO:1904659	Process	Glucose transmembrane transport	NAS	15793256
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:2000288	Process	Positive regulation of myoblast proliferation	IEA

MIM	HGNC	e!Ensembl
600409	9235	ENSG00000112033

Protein

UniProt ID

Q03181

Protein name

Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta)

Protein function

Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues (PubMed:35675826). Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty a

PDB

1GWX , 1Y0S , 2AWH , 2B50 , 2BAW , 2ENV , 2GWX , 2J14 , 2Q5G , 2XYJ , 2XYW , 2XYX , 2ZNP , 2ZNQ , 3D5F , 3DY6 , 3ET2 , 3GWX , 3GZ9 , 3OZ0 , 3PEQ , 3SP9 , 3TKM , 5U3Q , 5U3R , 5U3S , 5U3T , 5U3U , 5U3V , 5U3W , 5U3X , 5U3Y , 5U3Z , 5U40 , 5U41 , 5U42 , 5U43 , 5U44 , 5U45 , 5U46 , 5XMX , 5Y7X , 5ZXI , 6A6P , 7F80 , 7VWE , 7VWF , 7VWG , 7VWH , 7W0G , 7WGL

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00105	zf-C4	72 → 140	Zinc finger, C4 type (two domains)	Domain
PF00104	Hormone_recep	236 → 422	Ligand-binding domain of nuclear hormone receptor	Domain

Sequence

MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY

Sequence length

441

Interactions

View interactions

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