Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
8864 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Period circadian regulator 2 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
PER2 |
SynonymsGene synonyms aliases
|
FASPS, FASPS1 |
ChromosomeChromosome number
|
2 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
2q37.3 |
SummarySummary of gene provided in NCBI Entrez Gene.
|
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomoto |
SNPsSNP information provided by dbSNP.
|
SNP ID |
Visualize variation |
Clinical significance |
Consequence |
rs121908635 |
T>C |
Pathogenic |
Coding sequence variant, missense variant |
rs1559332542 |
G>- |
Pathogenic |
Coding sequence variant, frameshift variant |
|
miRNAmiRNA information provided by mirtarbase database.
|
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Transcription factors
|
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
O15055 |
Protein name |
Period circadian protein homolog 2 (hPER2) (Circadian clock protein PERIOD 2) |
Protein function |
Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in g |
PDB |
6OF7
,
8D7M
,
8D7N
,
8D7O
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF08447 |
PAS_3 |
344 → 432 |
PAS fold |
Domain |
PF12114 |
Period_C |
1046 → 1232 |
Period protein 2/3C-terminal region |
Family |
|
Sequence |
|
Sequence length |
1255 |
Interactions |
View interactions |