MMP2 (matrix metallopeptidase 2)

Gene

• Entrez ID: 4313
• Gene name: Matrix metallopeptidase 2
• Gene symbol: MMP2
• Synonyms: CLG4, CLG4A, MMP-2, MMP-II, MONA, TBE-1
• Chromosome: 16
• Chromosome location: 16q12.2
• Summary: This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelati

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs41459945	G>A,C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant
rs121912953	G>A	Pathogenic	Coding sequence variant, missense variant
rs121912954	C>A,G	Pathogenic	Coding sequence variant, stop gained
rs121912955	G>A	Pathogenic	Coding sequence variant, missense variant
rs140172728	G>A	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Synonymous variant, coding sequence variant
rs148801200	C>A,T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant, synonymous variant
rs786205497	G>A	Likely-pathogenic	Coding sequence variant, missense variant
rs794727275	C>-	Pathogenic	Coding sequence variant, frameshift variant
rs794727916	G>-	Pathogenic	Coding sequence variant, frameshift variant
rs1567378779	C>-	Pathogenic	Frameshift variant, coding sequence variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	20657750
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	20657750
MIRT005742	hsa-miR-451a	qRT-PCR, Western blot	20816946
MIRT005570	hsa-miR-29b-3p	Western blot	23254643
MIRT018099	hsa-miR-335-5p	Microarray	18185580
MIRT019228	hsa-miR-338-3p	Western blot;qRT-PCR	21671467
MIRT030716	hsa-miR-21-5p	qRT-PCR	19435867
MIRT031370	hsa-miR-17-5p	Western blot	20209605
MIRT005570	hsa-miR-29b-3p	Western blot	24130681
MIRT053245	hsa-miR-29c-3p	qRT-PCR, Western blot	23175151
MIRT053336	hsa-miR-491-5p	Immunohistochemistry, Microarray, qRT-PCR, Western blot	23725476
MIRT053481	hsa-miR-9-5p	qRT-PCR	21931274
MIRT053580	hsa-miR-29a-3p	Immunofluorescence, Immunohistochemistry, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	24130168
MIRT053580	hsa-miR-29a-3p	Immunofluorescence, Immunohistochemistry, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	24130168
MIRT005570	hsa-miR-29b-3p	Immunofluorescence, Immunohistochemistry, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	24130168
MIRT005570	hsa-miR-29b-3p	Immunofluorescence, Immunohistochemistry, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	24130168
MIRT053245	hsa-miR-29c-3p	Immunofluorescence, Immunohistochemistry, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	24130168
MIRT053245	hsa-miR-29c-3p	Immunofluorescence, Immunohistochemistry, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	24130168
MIRT005570	hsa-miR-29b-3p	Microarray	22942087
MIRT053787	hsa-miR-452-5p	Microarray, qRT-PCR	22952876
MIRT437388	hsa-miR-708-5p	Flow, qRT-PCR, Western blot	23754151
MIRT053580	hsa-miR-29a-3p	Luciferase reporter assay	22745231
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay	22745231
MIRT053245	hsa-miR-29c-3p	Luciferase reporter assay	22745231
MIRT437572	hsa-miR-767-5p	Luciferase reporter assay	22745231
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR	23354167
MIRT005570	hsa-miR-29b-3p	Western blot	24147037
MIRT438234	hsa-miR-221-3p	Western blot	24147037
MIRT438153	hsa-miR-106b-5p	Luciferase reporter assay	24164962
MIRT438153	hsa-miR-106b-5p	Luciferase reporter assay	24164962
MIRT438153	hsa-miR-106b-5p	Luciferase reporter assay	24164962
MIRT438153	hsa-miR-106b-5p	Luciferase reporter assay	24164962
MIRT053245	hsa-miR-29c-3p	Luciferase reporter assay, qRT-PCR, Western blot	23936390
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR	23354167
MIRT005570	hsa-miR-29b-3p	Western blot	24147037
MIRT438234	hsa-miR-221-3p	Western blot	24147037
MIRT438153	hsa-miR-106b-5p	Luciferase reporter assay	24164962
MIRT438153	hsa-miR-106b-5p	Luciferase reporter assay	24164962
MIRT438153	hsa-miR-106b-5p	Luciferase reporter assay	24164962
MIRT438153	hsa-miR-106b-5p	Luciferase reporter assay	24164962
MIRT053245	hsa-miR-29c-3p	Luciferase reporter assay, qRT-PCR, Western blot	23936390
MIRT724938	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT724937	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT724936	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT724935	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT724934	hsa-miR-670-3p	HITS-CLIP	19536157
MIRT724933	hsa-miR-1238-3p	HITS-CLIP	19536157
MIRT440222	hsa-miR-544a	HITS-CLIP	24374217
MIRT440222	hsa-miR-544a	HITS-CLIP	24374217
MIRT731061	hsa-miR-130b-3p	qRT-PCR, Luciferase reporter assay, Western blot	25154741
MIRT731061	hsa-miR-130b-3p	qRT-PCR, Luciferase reporter assay, Western blot	25154741
MIRT731453	hsa-miR-125b-5p	Luciferase reporter assay	27133077
MIRT731453	hsa-miR-125b-5p	Luciferase reporter assay	27133077
MIRT053580	hsa-miR-29a-3p	Luciferase reporter assay	26700017
MIRT005742	hsa-miR-451a	qRT-PCR, Western blot	27173190
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT005570	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	26063204
MIRT732484	hsa-miR-20a-3p	Luciferase reporter assay, qRT-PCR, Western blotting	33788053
MIRT732713	hsa-miR-34a-5p	qRT-PCR	33773546
MIRT732990	hsa-miR-1237-3p	Microarray	33435900
MIRT438153	hsa-miR-106b-5p	Luciferase reporter assay, qRT-PCR	32699607
MIRT019228	hsa-miR-338-3p	Luciferase reporter assay, Western blotting, qRT-PCR, Flow cytometry	33817311
MIRT732484	hsa-miR-20a-3p	Western blotting, Immunoprecipitaion (IP), qRT-PCR	33788053
MIRT737478	hsa-miR-200a-3p	Luciferase reporter assay, Western blotting, qRT-PCR	31772330
MIRT724938	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT724937	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT724936	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT724935	hsa-miR-29b-2-5p	HITS-CLIP	19536157
MIRT724934	hsa-miR-670-3p	HITS-CLIP	19536157
MIRT724933	hsa-miR-1238-3p	HITS-CLIP	19536157
MIRT755535	hsa-miR-149-5p	qRT-PCR	36250208
MIRT755915	hsa-miR-145-5p	Luciferase reporter assay, Western blotting, qRT-PCR	35722425
MIRT756341	hsa-miR-518a-5p	Western blotting, qRT-PCR	37132750
MIRT756431	hsa-miR-146a-5p	qRT-PCR	36415628
MIRT756466	hsa-miR-182-5p	qRT-PCR	38796528
MIRT1153360	hsa-miR-1324	CLIP-seq
MIRT1153361	hsa-miR-3164	CLIP-seq
MIRT1153362	hsa-miR-3944-5p	CLIP-seq
MIRT1153363	hsa-miR-617	CLIP-seq
MIRT1153364	hsa-miR-296-3p	CLIP-seq
MIRT1153365	hsa-miR-3921	CLIP-seq
MIRT1153366	hsa-miR-4443	CLIP-seq
MIRT1153367	hsa-miR-4649-3p	CLIP-seq
MIRT1153368	hsa-miR-4653-5p	CLIP-seq
MIRT1153369	hsa-miR-4654	CLIP-seq
MIRT1153370	hsa-miR-4769-5p	CLIP-seq
MIRT1153371	hsa-miR-541	CLIP-seq
MIRT1153372	hsa-miR-654-5p	CLIP-seq
MIRT1551365	hsa-miR-330-3p	CLIP-seq
MIRT1551366	hsa-miR-4685-5p	CLIP-seq
MIRT1551367	hsa-miR-520g	CLIP-seq
MIRT1551368	hsa-miR-520h	CLIP-seq
MIRT2043917	hsa-miR-765	CLIP-seq
MIRT2273303	hsa-miR-29a	CLIP-seq
MIRT2273304	hsa-miR-29b	CLIP-seq
MIRT2273305	hsa-miR-29c	CLIP-seq
MIRT2273306	hsa-miR-3065-3p	CLIP-seq
MIRT1551365	hsa-miR-330-3p	CLIP-seq
MIRT2273307	hsa-miR-4436b-3p	CLIP-seq
MIRT1551366	hsa-miR-4685-5p	CLIP-seq
MIRT2273308	hsa-miR-4690-3p	CLIP-seq
MIRT2273309	hsa-miR-4733-3p	CLIP-seq
MIRT2431185	hsa-miR-106a	CLIP-seq
MIRT2431186	hsa-miR-106b	CLIP-seq
MIRT2431187	hsa-miR-124	CLIP-seq
MIRT2431188	hsa-miR-17	CLIP-seq
MIRT2431189	hsa-miR-20a	CLIP-seq
MIRT2431190	hsa-miR-20b	CLIP-seq
MIRT2431191	hsa-miR-2110	CLIP-seq
MIRT1153364	hsa-miR-296-3p	CLIP-seq
MIRT2431192	hsa-miR-3179	CLIP-seq
MIRT2431193	hsa-miR-3202	CLIP-seq
MIRT1551365	hsa-miR-330-3p	CLIP-seq
MIRT2431194	hsa-miR-3616-5p	CLIP-seq
MIRT2431195	hsa-miR-3647-5p	CLIP-seq
MIRT2431196	hsa-miR-3688-5p	CLIP-seq
MIRT2431197	hsa-miR-3714	CLIP-seq
MIRT2431198	hsa-miR-3910	CLIP-seq
MIRT2431199	hsa-miR-4263	CLIP-seq
MIRT2431200	hsa-miR-4271	CLIP-seq
MIRT2431201	hsa-miR-4293	CLIP-seq
MIRT1153366	hsa-miR-4443	CLIP-seq
MIRT2431202	hsa-miR-4519	CLIP-seq
MIRT2431203	hsa-miR-4521	CLIP-seq
MIRT2431204	hsa-miR-4530	CLIP-seq
MIRT1153369	hsa-miR-4654	CLIP-seq
MIRT2431205	hsa-miR-4716-3p	CLIP-seq
MIRT2431206	hsa-miR-4725-3p	CLIP-seq
MIRT2431207	hsa-miR-4747-5p	CLIP-seq
MIRT1153370	hsa-miR-4769-5p	CLIP-seq
MIRT2431208	hsa-miR-4790-3p	CLIP-seq
MIRT2431209	hsa-miR-4795-5p	CLIP-seq
MIRT2431210	hsa-miR-506	CLIP-seq
MIRT2431211	hsa-miR-519a	CLIP-seq
MIRT2431212	hsa-miR-519b-3p	CLIP-seq
MIRT2431213	hsa-miR-519c-3p	CLIP-seq
MIRT2431214	hsa-miR-519d	CLIP-seq
MIRT2431215	hsa-miR-520d-5p	CLIP-seq
MIRT1551367	hsa-miR-520g	CLIP-seq
MIRT1551368	hsa-miR-520h	CLIP-seq
MIRT1153371	hsa-miR-541	CLIP-seq
MIRT2431216	hsa-miR-563	CLIP-seq
MIRT2431217	hsa-miR-573	CLIP-seq
MIRT2431218	hsa-miR-595	CLIP-seq
MIRT2431219	hsa-miR-625	CLIP-seq
MIRT2431220	hsa-miR-644	CLIP-seq
MIRT1153372	hsa-miR-654-5p	CLIP-seq
MIRT2431221	hsa-miR-885-3p	CLIP-seq
MIRT2431222	hsa-miR-93	CLIP-seq
MIRT2438718	hsa-miR-1207-5p	CLIP-seq
MIRT2438719	hsa-miR-1238	CLIP-seq
MIRT2438720	hsa-miR-1253	CLIP-seq
MIRT2438721	hsa-miR-1273f	CLIP-seq
MIRT2438722	hsa-miR-1321	CLIP-seq
MIRT1153360	hsa-miR-1324	CLIP-seq
MIRT2438723	hsa-miR-136	CLIP-seq
MIRT2438724	hsa-miR-143	CLIP-seq
MIRT2438725	hsa-miR-1587	CLIP-seq
MIRT2438726	hsa-miR-1825	CLIP-seq
MIRT2438727	hsa-miR-199a-3p	CLIP-seq
MIRT2438728	hsa-miR-199a-5p	CLIP-seq
MIRT2438729	hsa-miR-199b-3p	CLIP-seq
MIRT2438730	hsa-miR-199b-5p	CLIP-seq
MIRT2431191	hsa-miR-2110	CLIP-seq
MIRT2438731	hsa-miR-299-3p	CLIP-seq
MIRT2438732	hsa-miR-3129-5p	CLIP-seq
MIRT1153361	hsa-miR-3164	CLIP-seq
MIRT2431192	hsa-miR-3179	CLIP-seq
MIRT2438733	hsa-miR-3184	CLIP-seq
MIRT2438734	hsa-miR-34c-3p	CLIP-seq
MIRT1153362	hsa-miR-3944-5p	CLIP-seq
MIRT2438735	hsa-miR-423-5p	CLIP-seq
MIRT2438736	hsa-miR-4265	CLIP-seq
MIRT2438737	hsa-miR-4270	CLIP-seq
MIRT2431200	hsa-miR-4271	CLIP-seq
MIRT2438738	hsa-miR-4296	CLIP-seq
MIRT2438739	hsa-miR-4322	CLIP-seq
MIRT2438740	hsa-miR-4417	CLIP-seq
MIRT2438741	hsa-miR-4434	CLIP-seq
MIRT2438742	hsa-miR-4441	CLIP-seq
MIRT2438743	hsa-miR-4446-3p	CLIP-seq
MIRT2438744	hsa-miR-4491	CLIP-seq
MIRT2438745	hsa-miR-4492	CLIP-seq
MIRT2438746	hsa-miR-4498	CLIP-seq
MIRT2438747	hsa-miR-4516	CLIP-seq
MIRT2438748	hsa-miR-4531	CLIP-seq
MIRT2438749	hsa-miR-4639-5p	CLIP-seq
MIRT2438750	hsa-miR-4656	CLIP-seq
MIRT2438751	hsa-miR-4657	CLIP-seq
MIRT2438752	hsa-miR-4663	CLIP-seq
MIRT2438753	hsa-miR-4675	CLIP-seq
MIRT2438754	hsa-miR-4677-3p	CLIP-seq
MIRT2438755	hsa-miR-4679	CLIP-seq
MIRT2438756	hsa-miR-4688	CLIP-seq
MIRT2438757	hsa-miR-4708-5p	CLIP-seq
MIRT2438758	hsa-miR-4711-3p	CLIP-seq
MIRT2438759	hsa-miR-4721	CLIP-seq
MIRT2431206	hsa-miR-4725-3p	CLIP-seq
MIRT2438760	hsa-miR-4728-5p	CLIP-seq
MIRT2438761	hsa-miR-4739	CLIP-seq
MIRT2438762	hsa-miR-4741	CLIP-seq
MIRT2438763	hsa-miR-4755-3p	CLIP-seq
MIRT2438764	hsa-miR-4756-5p	CLIP-seq
MIRT2438765	hsa-miR-4763-3p	CLIP-seq
MIRT2438766	hsa-miR-4770	CLIP-seq
MIRT2438767	hsa-miR-4786-3p	CLIP-seq
MIRT2431208	hsa-miR-4790-3p	CLIP-seq
MIRT2438768	hsa-miR-4797-3p	CLIP-seq
MIRT2438769	hsa-miR-485-3p	CLIP-seq
MIRT2438770	hsa-miR-486-3p	CLIP-seq
MIRT2438771	hsa-miR-511	CLIP-seq
MIRT2438772	hsa-miR-562	CLIP-seq
MIRT2431216	hsa-miR-563	CLIP-seq
MIRT1153363	hsa-miR-617	CLIP-seq
MIRT2438773	hsa-miR-664	CLIP-seq
MIRT2438774	hsa-miR-671-5p	CLIP-seq
MIRT2438775	hsa-miR-762	CLIP-seq
MIRT2438776	hsa-miR-936	CLIP-seq
MIRT2431185	hsa-miR-106a	CLIP-seq
MIRT2431186	hsa-miR-106b	CLIP-seq
MIRT2572098	hsa-miR-1179	CLIP-seq
MIRT2572099	hsa-miR-1206	CLIP-seq
MIRT2438718	hsa-miR-1207-5p	CLIP-seq
MIRT2572100	hsa-miR-122	CLIP-seq
MIRT2572101	hsa-miR-1227	CLIP-seq
MIRT2572102	hsa-miR-1237	CLIP-seq
MIRT2438719	hsa-miR-1238	CLIP-seq
MIRT2431187	hsa-miR-124	CLIP-seq
MIRT2572103	hsa-miR-1244	CLIP-seq
MIRT2572104	hsa-miR-1248	CLIP-seq
MIRT2572105	hsa-miR-1251	CLIP-seq
MIRT2438720	hsa-miR-1253	CLIP-seq
MIRT2438721	hsa-miR-1273f	CLIP-seq
MIRT2572106	hsa-miR-1276	CLIP-seq
MIRT2572107	hsa-miR-1299	CLIP-seq
MIRT2438722	hsa-miR-1321	CLIP-seq
MIRT1153360	hsa-miR-1324	CLIP-seq
MIRT2438723	hsa-miR-136	CLIP-seq
MIRT2572108	hsa-miR-139-5p	CLIP-seq
MIRT2438724	hsa-miR-143	CLIP-seq
MIRT2572109	hsa-miR-146b-3p	CLIP-seq
MIRT2572110	hsa-miR-1470	CLIP-seq
MIRT2572111	hsa-miR-1538	CLIP-seq
MIRT2438725	hsa-miR-1587	CLIP-seq
MIRT2431188	hsa-miR-17	CLIP-seq
MIRT2438726	hsa-miR-1825	CLIP-seq
MIRT2572112	hsa-miR-190	CLIP-seq
MIRT2572113	hsa-miR-190b	CLIP-seq
MIRT2572114	hsa-miR-1914	CLIP-seq
MIRT2438728	hsa-miR-199a-5p	CLIP-seq
MIRT2438730	hsa-miR-199b-5p	CLIP-seq
MIRT2431189	hsa-miR-20a	CLIP-seq
MIRT2431190	hsa-miR-20b	CLIP-seq
MIRT2431191	hsa-miR-2110	CLIP-seq
MIRT2572115	hsa-miR-2909	CLIP-seq
MIRT1153364	hsa-miR-296-3p	CLIP-seq
MIRT2438731	hsa-miR-299-3p	CLIP-seq
MIRT2273303	hsa-miR-29a	CLIP-seq
MIRT2273304	hsa-miR-29b	CLIP-seq
MIRT2273305	hsa-miR-29c	CLIP-seq
MIRT2572116	hsa-miR-302f	CLIP-seq
MIRT2572117	hsa-miR-3064-3p	CLIP-seq
MIRT2273306	hsa-miR-3065-3p	CLIP-seq
MIRT2572118	hsa-miR-3065-5p	CLIP-seq
MIRT2572119	hsa-miR-3125	CLIP-seq
MIRT2572120	hsa-miR-3127-5p	CLIP-seq
MIRT2572121	hsa-miR-3148	CLIP-seq
MIRT2572122	hsa-miR-3156-3p	CLIP-seq
MIRT2572123	hsa-miR-3160-3p	CLIP-seq
MIRT1153361	hsa-miR-3164	CLIP-seq
MIRT2572124	hsa-miR-3168	CLIP-seq
MIRT2572125	hsa-miR-3173-5p	CLIP-seq
MIRT2572126	hsa-miR-3177-3p	CLIP-seq
MIRT2431192	hsa-miR-3179	CLIP-seq
MIRT2572127	hsa-miR-3181	CLIP-seq
MIRT2572128	hsa-miR-3182	CLIP-seq
MIRT2438733	hsa-miR-3184	CLIP-seq
MIRT2572129	hsa-miR-3185	CLIP-seq
MIRT2572130	hsa-miR-3187-3p	CLIP-seq
MIRT2572131	hsa-miR-3192	CLIP-seq
MIRT2431193	hsa-miR-3202	CLIP-seq
MIRT2572132	hsa-miR-326	CLIP-seq
MIRT1551365	hsa-miR-330-3p	CLIP-seq
MIRT2572133	hsa-miR-330-5p	CLIP-seq
MIRT2572134	hsa-miR-339-5p	CLIP-seq
MIRT2438734	hsa-miR-34c-3p	CLIP-seq
MIRT2572135	hsa-miR-3611	CLIP-seq
MIRT2431194	hsa-miR-3616-5p	CLIP-seq
MIRT2572136	hsa-miR-3622a-5p	CLIP-seq
MIRT2572137	hsa-miR-3647-3p	CLIP-seq
MIRT2431195	hsa-miR-3647-5p	CLIP-seq
MIRT2572138	hsa-miR-3667-5p	CLIP-seq
MIRT2572139	hsa-miR-3672	CLIP-seq
MIRT2572140	hsa-miR-3675-3p	CLIP-seq
MIRT2572141	hsa-miR-3677-5p	CLIP-seq
MIRT2431196	hsa-miR-3688-5p	CLIP-seq
MIRT2572142	hsa-miR-3689a-3p	CLIP-seq
MIRT2572143	hsa-miR-3689c	CLIP-seq
MIRT2431197	hsa-miR-3714	CLIP-seq
MIRT2572144	hsa-miR-371b-3p	CLIP-seq
MIRT2572145	hsa-miR-376c	CLIP-seq
MIRT2431198	hsa-miR-3910	CLIP-seq
MIRT2572146	hsa-miR-3916	CLIP-seq
MIRT2572147	hsa-miR-3918	CLIP-seq
MIRT2572148	hsa-miR-3920	CLIP-seq
MIRT1153365	hsa-miR-3921	CLIP-seq
MIRT2572149	hsa-miR-3925-3p	CLIP-seq
MIRT2572150	hsa-miR-3973	CLIP-seq
MIRT2438735	hsa-miR-423-5p	CLIP-seq
MIRT2431199	hsa-miR-4263	CLIP-seq
MIRT2438736	hsa-miR-4265	CLIP-seq
MIRT2438737	hsa-miR-4270	CLIP-seq
MIRT2431200	hsa-miR-4271	CLIP-seq
MIRT2572151	hsa-miR-4278	CLIP-seq
MIRT2572152	hsa-miR-4289	CLIP-seq
MIRT2572153	hsa-miR-4290	CLIP-seq
MIRT2431201	hsa-miR-4293	CLIP-seq
MIRT2438738	hsa-miR-4296	CLIP-seq
MIRT2572154	hsa-miR-4301	CLIP-seq
MIRT2572155	hsa-miR-4310	CLIP-seq
MIRT2572156	hsa-miR-4311	CLIP-seq
MIRT2438739	hsa-miR-4322	CLIP-seq
MIRT2438740	hsa-miR-4417	CLIP-seq
MIRT2572157	hsa-miR-4422	CLIP-seq
MIRT2572158	hsa-miR-4428	CLIP-seq
MIRT2438741	hsa-miR-4434	CLIP-seq
MIRT2572159	hsa-miR-4436a	CLIP-seq
MIRT2273307	hsa-miR-4436b-3p	CLIP-seq
MIRT2438742	hsa-miR-4441	CLIP-seq
MIRT1153366	hsa-miR-4443	CLIP-seq
MIRT2438743	hsa-miR-4446-3p	CLIP-seq
MIRT2438744	hsa-miR-4491	CLIP-seq
MIRT2438745	hsa-miR-4492	CLIP-seq
MIRT2572160	hsa-miR-4493	CLIP-seq
MIRT2438746	hsa-miR-4498	CLIP-seq
MIRT2438747	hsa-miR-4516	CLIP-seq
MIRT2431202	hsa-miR-4519	CLIP-seq
MIRT2572161	hsa-miR-452	CLIP-seq
MIRT2431203	hsa-miR-4521	CLIP-seq
MIRT2572162	hsa-miR-4525	CLIP-seq
MIRT2572163	hsa-miR-4529-5p	CLIP-seq
MIRT2431204	hsa-miR-4530	CLIP-seq
MIRT2438748	hsa-miR-4531	CLIP-seq
MIRT2572164	hsa-miR-4639-3p	CLIP-seq
MIRT2438749	hsa-miR-4639-5p	CLIP-seq
MIRT2572165	hsa-miR-4645-5p	CLIP-seq
MIRT1153367	hsa-miR-4649-3p	CLIP-seq
MIRT2572166	hsa-miR-4651	CLIP-seq
MIRT1153368	hsa-miR-4653-5p	CLIP-seq
MIRT1153369	hsa-miR-4654	CLIP-seq
MIRT2438750	hsa-miR-4656	CLIP-seq
MIRT2438751	hsa-miR-4657	CLIP-seq
MIRT2438752	hsa-miR-4663	CLIP-seq
MIRT2572167	hsa-miR-4673	CLIP-seq
MIRT2438753	hsa-miR-4675	CLIP-seq
MIRT2572168	hsa-miR-4676-3p	CLIP-seq
MIRT2438754	hsa-miR-4677-3p	CLIP-seq
MIRT2438755	hsa-miR-4679	CLIP-seq
MIRT2572169	hsa-miR-4684-5p	CLIP-seq
MIRT1551366	hsa-miR-4685-5p	CLIP-seq
MIRT2438756	hsa-miR-4688	CLIP-seq
MIRT2273308	hsa-miR-4690-3p	CLIP-seq
MIRT2572170	hsa-miR-4693-5p	CLIP-seq
MIRT2572171	hsa-miR-4700-3p	CLIP-seq
MIRT2572172	hsa-miR-4701-5p	CLIP-seq
MIRT2438757	hsa-miR-4708-5p	CLIP-seq
MIRT2431205	hsa-miR-4716-3p	CLIP-seq
MIRT2438759	hsa-miR-4721	CLIP-seq
MIRT2431206	hsa-miR-4725-3p	CLIP-seq
MIRT2572173	hsa-miR-4728-3p	CLIP-seq
MIRT2438760	hsa-miR-4728-5p	CLIP-seq
MIRT2572174	hsa-miR-4732-5p	CLIP-seq
MIRT2273309	hsa-miR-4733-3p	CLIP-seq
MIRT2438761	hsa-miR-4739	CLIP-seq
MIRT2438762	hsa-miR-4741	CLIP-seq
MIRT2572175	hsa-miR-4745-3p	CLIP-seq
MIRT2572176	hsa-miR-4747-3p	CLIP-seq
MIRT2431207	hsa-miR-4747-5p	CLIP-seq
MIRT2572177	hsa-miR-4749-3p	CLIP-seq
MIRT2572178	hsa-miR-4753-3p	CLIP-seq
MIRT2438763	hsa-miR-4755-3p	CLIP-seq
MIRT2438764	hsa-miR-4756-5p	CLIP-seq
MIRT2438765	hsa-miR-4763-3p	CLIP-seq
MIRT1153370	hsa-miR-4769-5p	CLIP-seq
MIRT2438766	hsa-miR-4770	CLIP-seq
MIRT2572179	hsa-miR-4783-3p	CLIP-seq
MIRT2438767	hsa-miR-4786-3p	CLIP-seq
MIRT2431208	hsa-miR-4790-3p	CLIP-seq
MIRT2572180	hsa-miR-4795-3p	CLIP-seq
MIRT2431209	hsa-miR-4795-5p	CLIP-seq
MIRT2438770	hsa-miR-486-3p	CLIP-seq
MIRT2572181	hsa-miR-488	CLIP-seq
MIRT2572182	hsa-miR-499a-5p	CLIP-seq
MIRT2431210	hsa-miR-506	CLIP-seq
MIRT2572183	hsa-miR-515-5p	CLIP-seq
MIRT2572184	hsa-miR-516b	CLIP-seq
MIRT2431211	hsa-miR-519a	CLIP-seq
MIRT2431212	hsa-miR-519b-3p	CLIP-seq
MIRT2431213	hsa-miR-519c-3p	CLIP-seq
MIRT2431214	hsa-miR-519d	CLIP-seq
MIRT2431215	hsa-miR-520d-5p	CLIP-seq
MIRT1551367	hsa-miR-520g	CLIP-seq
MIRT1551368	hsa-miR-520h	CLIP-seq
MIRT2572185	hsa-miR-526b	CLIP-seq
MIRT1153371	hsa-miR-541	CLIP-seq
MIRT2572186	hsa-miR-548a-3p	CLIP-seq
MIRT2572187	hsa-miR-548e	CLIP-seq
MIRT2572188	hsa-miR-548f	CLIP-seq
MIRT2572189	hsa-miR-548l	CLIP-seq
MIRT2438772	hsa-miR-562	CLIP-seq
MIRT2431216	hsa-miR-563	CLIP-seq
MIRT2572190	hsa-miR-564	CLIP-seq
MIRT2572191	hsa-miR-566	CLIP-seq
MIRT2431217	hsa-miR-573	CLIP-seq
MIRT2572192	hsa-miR-580	CLIP-seq
MIRT2572193	hsa-miR-583	CLIP-seq
MIRT2572194	hsa-miR-588	CLIP-seq
MIRT2431218	hsa-miR-595	CLIP-seq
MIRT2572195	hsa-miR-604	CLIP-seq
MIRT2572196	hsa-miR-608	CLIP-seq
MIRT1153363	hsa-miR-617	CLIP-seq
MIRT2431219	hsa-miR-625	CLIP-seq
MIRT2572197	hsa-miR-628-5p	CLIP-seq
MIRT2572198	hsa-miR-635	CLIP-seq
MIRT2431220	hsa-miR-644	CLIP-seq
MIRT1153372	hsa-miR-654-5p	CLIP-seq
MIRT2572199	hsa-miR-656	CLIP-seq
MIRT2572200	hsa-miR-661	CLIP-seq
MIRT2438774	hsa-miR-671-5p	CLIP-seq
MIRT2572201	hsa-miR-760	CLIP-seq
MIRT2438775	hsa-miR-762	CLIP-seq
MIRT2043917	hsa-miR-765	CLIP-seq
MIRT2572202	hsa-miR-766	CLIP-seq
MIRT2572203	hsa-miR-873	CLIP-seq
MIRT2572204	hsa-miR-874	CLIP-seq
MIRT2572205	hsa-miR-875-3p	CLIP-seq
MIRT2431221	hsa-miR-885-3p	CLIP-seq
MIRT2431222	hsa-miR-93	CLIP-seq
MIRT2572206	hsa-miR-942	CLIP-seq
MIRT2431185	hsa-miR-106a	CLIP-seq
MIRT2431186	hsa-miR-106b	CLIP-seq
MIRT2572098	hsa-miR-1179	CLIP-seq
MIRT2572099	hsa-miR-1206	CLIP-seq
MIRT2438718	hsa-miR-1207-5p	CLIP-seq
MIRT2572100	hsa-miR-122	CLIP-seq
MIRT2572101	hsa-miR-1227	CLIP-seq
MIRT2572102	hsa-miR-1237	CLIP-seq
MIRT2438719	hsa-miR-1238	CLIP-seq
MIRT2431187	hsa-miR-124	CLIP-seq
MIRT2572103	hsa-miR-1244	CLIP-seq
MIRT2572104	hsa-miR-1248	CLIP-seq
MIRT2572105	hsa-miR-1251	CLIP-seq
MIRT2438720	hsa-miR-1253	CLIP-seq
MIRT2685138	hsa-miR-125a-5p	CLIP-seq
MIRT2685139	hsa-miR-125b	CLIP-seq
MIRT2438721	hsa-miR-1273f	CLIP-seq
MIRT2572106	hsa-miR-1276	CLIP-seq
MIRT2572107	hsa-miR-1299	CLIP-seq
MIRT2438722	hsa-miR-1321	CLIP-seq
MIRT1153360	hsa-miR-1324	CLIP-seq
MIRT2438723	hsa-miR-136	CLIP-seq
MIRT2572108	hsa-miR-139-5p	CLIP-seq
MIRT2438724	hsa-miR-143	CLIP-seq
MIRT2572109	hsa-miR-146b-3p	CLIP-seq
MIRT2572110	hsa-miR-1470	CLIP-seq
MIRT2572111	hsa-miR-1538	CLIP-seq
MIRT2438725	hsa-miR-1587	CLIP-seq
MIRT2431188	hsa-miR-17	CLIP-seq
MIRT2438726	hsa-miR-1825	CLIP-seq
MIRT2572112	hsa-miR-190	CLIP-seq
MIRT2572113	hsa-miR-190b	CLIP-seq
MIRT2572114	hsa-miR-1914	CLIP-seq
MIRT2438728	hsa-miR-199a-5p	CLIP-seq
MIRT2438730	hsa-miR-199b-5p	CLIP-seq
MIRT2431189	hsa-miR-20a	CLIP-seq
MIRT2431190	hsa-miR-20b	CLIP-seq
MIRT2431191	hsa-miR-2110	CLIP-seq
MIRT2685140	hsa-miR-2117	CLIP-seq
MIRT2572115	hsa-miR-2909	CLIP-seq
MIRT1153364	hsa-miR-296-3p	CLIP-seq
MIRT2438731	hsa-miR-299-3p	CLIP-seq
MIRT2273303	hsa-miR-29a	CLIP-seq
MIRT2273304	hsa-miR-29b	CLIP-seq
MIRT2273305	hsa-miR-29c	CLIP-seq
MIRT2572116	hsa-miR-302f	CLIP-seq
MIRT2572117	hsa-miR-3064-3p	CLIP-seq
MIRT2273306	hsa-miR-3065-3p	CLIP-seq
MIRT2572118	hsa-miR-3065-5p	CLIP-seq
MIRT2572119	hsa-miR-3125	CLIP-seq
MIRT2685141	hsa-miR-3126-5p	CLIP-seq
MIRT2572120	hsa-miR-3127-5p	CLIP-seq
MIRT2572121	hsa-miR-3148	CLIP-seq
MIRT2685142	hsa-miR-3150a-5p	CLIP-seq
MIRT2685143	hsa-miR-3150b-5p	CLIP-seq
MIRT2572122	hsa-miR-3156-3p	CLIP-seq
MIRT2572123	hsa-miR-3160-3p	CLIP-seq
MIRT1153361	hsa-miR-3164	CLIP-seq
MIRT2572124	hsa-miR-3168	CLIP-seq
MIRT2572125	hsa-miR-3173-5p	CLIP-seq
MIRT2572126	hsa-miR-3177-3p	CLIP-seq
MIRT2431192	hsa-miR-3179	CLIP-seq
MIRT2572127	hsa-miR-3181	CLIP-seq
MIRT2572128	hsa-miR-3182	CLIP-seq
MIRT2438733	hsa-miR-3184	CLIP-seq
MIRT2572129	hsa-miR-3185	CLIP-seq
MIRT2572130	hsa-miR-3187-3p	CLIP-seq
MIRT2572131	hsa-miR-3192	CLIP-seq
MIRT2431193	hsa-miR-3202	CLIP-seq
MIRT2572132	hsa-miR-326	CLIP-seq
MIRT1551365	hsa-miR-330-3p	CLIP-seq
MIRT2572133	hsa-miR-330-5p	CLIP-seq
MIRT2572134	hsa-miR-339-5p	CLIP-seq
MIRT2438734	hsa-miR-34c-3p	CLIP-seq
MIRT2572135	hsa-miR-3611	CLIP-seq
MIRT2431194	hsa-miR-3616-5p	CLIP-seq
MIRT2572136	hsa-miR-3622a-5p	CLIP-seq
MIRT2572137	hsa-miR-3647-3p	CLIP-seq
MIRT2431195	hsa-miR-3647-5p	CLIP-seq
MIRT2572138	hsa-miR-3667-5p	CLIP-seq
MIRT2572139	hsa-miR-3672	CLIP-seq
MIRT2572140	hsa-miR-3675-3p	CLIP-seq
MIRT2572141	hsa-miR-3677-5p	CLIP-seq
MIRT2431196	hsa-miR-3688-5p	CLIP-seq
MIRT2572142	hsa-miR-3689a-3p	CLIP-seq
MIRT2572143	hsa-miR-3689c	CLIP-seq
MIRT2431197	hsa-miR-3714	CLIP-seq
MIRT2572144	hsa-miR-371b-3p	CLIP-seq
MIRT2572145	hsa-miR-376c	CLIP-seq
MIRT2431198	hsa-miR-3910	CLIP-seq
MIRT2572146	hsa-miR-3916	CLIP-seq
MIRT2572147	hsa-miR-3918	CLIP-seq
MIRT2572148	hsa-miR-3920	CLIP-seq
MIRT1153365	hsa-miR-3921	CLIP-seq
MIRT2572149	hsa-miR-3925-3p	CLIP-seq
MIRT1153362	hsa-miR-3944-5p	CLIP-seq
MIRT2572150	hsa-miR-3973	CLIP-seq
MIRT2438735	hsa-miR-423-5p	CLIP-seq
MIRT2431199	hsa-miR-4263	CLIP-seq
MIRT2438736	hsa-miR-4265	CLIP-seq
MIRT2438737	hsa-miR-4270	CLIP-seq
MIRT2431200	hsa-miR-4271	CLIP-seq
MIRT2572151	hsa-miR-4278	CLIP-seq
MIRT2685144	hsa-miR-4287	CLIP-seq
MIRT2572152	hsa-miR-4289	CLIP-seq
MIRT2572153	hsa-miR-4290	CLIP-seq
MIRT2431201	hsa-miR-4293	CLIP-seq
MIRT2438738	hsa-miR-4296	CLIP-seq
MIRT2572154	hsa-miR-4301	CLIP-seq
MIRT2572155	hsa-miR-4310	CLIP-seq
MIRT2572156	hsa-miR-4311	CLIP-seq
MIRT2685145	hsa-miR-4319	CLIP-seq
MIRT2438739	hsa-miR-4322	CLIP-seq
MIRT2438740	hsa-miR-4417	CLIP-seq
MIRT2572157	hsa-miR-4422	CLIP-seq
MIRT2572158	hsa-miR-4428	CLIP-seq
MIRT2438741	hsa-miR-4434	CLIP-seq
MIRT2572159	hsa-miR-4436a	CLIP-seq
MIRT2273307	hsa-miR-4436b-3p	CLIP-seq
MIRT2438742	hsa-miR-4441	CLIP-seq
MIRT1153366	hsa-miR-4443	CLIP-seq
MIRT2438743	hsa-miR-4446-3p	CLIP-seq
MIRT2685146	hsa-miR-4469	CLIP-seq
MIRT2438744	hsa-miR-4491	CLIP-seq
MIRT2438745	hsa-miR-4492	CLIP-seq
MIRT2572160	hsa-miR-4493	CLIP-seq
MIRT2438746	hsa-miR-4498	CLIP-seq
MIRT2438747	hsa-miR-4516	CLIP-seq
MIRT2431202	hsa-miR-4519	CLIP-seq
MIRT2572161	hsa-miR-452	CLIP-seq
MIRT2431203	hsa-miR-4521	CLIP-seq
MIRT2572162	hsa-miR-4525	CLIP-seq
MIRT2572163	hsa-miR-4529-5p	CLIP-seq
MIRT2431204	hsa-miR-4530	CLIP-seq
MIRT2438748	hsa-miR-4531	CLIP-seq
MIRT2572164	hsa-miR-4639-3p	CLIP-seq
MIRT2438749	hsa-miR-4639-5p	CLIP-seq
MIRT2572165	hsa-miR-4645-5p	CLIP-seq
MIRT1153367	hsa-miR-4649-3p	CLIP-seq
MIRT2572166	hsa-miR-4651	CLIP-seq
MIRT1153368	hsa-miR-4653-5p	CLIP-seq
MIRT1153369	hsa-miR-4654	CLIP-seq
MIRT2438750	hsa-miR-4656	CLIP-seq
MIRT2438751	hsa-miR-4657	CLIP-seq
MIRT2438752	hsa-miR-4663	CLIP-seq
MIRT2572167	hsa-miR-4673	CLIP-seq
MIRT2438753	hsa-miR-4675	CLIP-seq
MIRT2572168	hsa-miR-4676-3p	CLIP-seq
MIRT2438754	hsa-miR-4677-3p	CLIP-seq
MIRT2438755	hsa-miR-4679	CLIP-seq
MIRT2572169	hsa-miR-4684-5p	CLIP-seq
MIRT2685147	hsa-miR-4685-3p	CLIP-seq
MIRT1551366	hsa-miR-4685-5p	CLIP-seq
MIRT2438756	hsa-miR-4688	CLIP-seq
MIRT2273308	hsa-miR-4690-3p	CLIP-seq
MIRT2572170	hsa-miR-4693-5p	CLIP-seq
MIRT2572171	hsa-miR-4700-3p	CLIP-seq
MIRT2572172	hsa-miR-4701-5p	CLIP-seq
MIRT2438757	hsa-miR-4708-5p	CLIP-seq
MIRT2431205	hsa-miR-4716-3p	CLIP-seq
MIRT2438759	hsa-miR-4721	CLIP-seq
MIRT2431206	hsa-miR-4725-3p	CLIP-seq
MIRT2572173	hsa-miR-4728-3p	CLIP-seq
MIRT2438760	hsa-miR-4728-5p	CLIP-seq
MIRT2685148	hsa-miR-4732-3p	CLIP-seq
MIRT2572174	hsa-miR-4732-5p	CLIP-seq
MIRT2273309	hsa-miR-4733-3p	CLIP-seq
MIRT2438761	hsa-miR-4739	CLIP-seq
MIRT2438762	hsa-miR-4741	CLIP-seq
MIRT2572175	hsa-miR-4745-3p	CLIP-seq
MIRT2572176	hsa-miR-4747-3p	CLIP-seq
MIRT2431207	hsa-miR-4747-5p	CLIP-seq
MIRT2572177	hsa-miR-4749-3p	CLIP-seq
MIRT2572178	hsa-miR-4753-3p	CLIP-seq
MIRT2438763	hsa-miR-4755-3p	CLIP-seq
MIRT2438764	hsa-miR-4756-5p	CLIP-seq
MIRT2438765	hsa-miR-4763-3p	CLIP-seq
MIRT1153370	hsa-miR-4769-5p	CLIP-seq
MIRT2438766	hsa-miR-4770	CLIP-seq
MIRT2572179	hsa-miR-4783-3p	CLIP-seq
MIRT2438767	hsa-miR-4786-3p	CLIP-seq
MIRT2431208	hsa-miR-4790-3p	CLIP-seq
MIRT2572180	hsa-miR-4795-3p	CLIP-seq
MIRT2431209	hsa-miR-4795-5p	CLIP-seq
MIRT2438770	hsa-miR-486-3p	CLIP-seq
MIRT2572181	hsa-miR-488	CLIP-seq
MIRT2572182	hsa-miR-499a-5p	CLIP-seq
MIRT2431210	hsa-miR-506	CLIP-seq
MIRT2572183	hsa-miR-515-5p	CLIP-seq
MIRT2572184	hsa-miR-516b	CLIP-seq
MIRT2431211	hsa-miR-519a	CLIP-seq
MIRT2431212	hsa-miR-519b-3p	CLIP-seq
MIRT2431213	hsa-miR-519c-3p	CLIP-seq
MIRT2431214	hsa-miR-519d	CLIP-seq
MIRT2431215	hsa-miR-520d-5p	CLIP-seq
MIRT1551367	hsa-miR-520g	CLIP-seq
MIRT1551368	hsa-miR-520h	CLIP-seq
MIRT2572185	hsa-miR-526b	CLIP-seq
MIRT1153371	hsa-miR-541	CLIP-seq
MIRT2685149	hsa-miR-544b	CLIP-seq
MIRT2572186	hsa-miR-548a-3p	CLIP-seq
MIRT2572187	hsa-miR-548e	CLIP-seq
MIRT2572188	hsa-miR-548f	CLIP-seq
MIRT2572189	hsa-miR-548l	CLIP-seq
MIRT2685150	hsa-miR-550b	CLIP-seq
MIRT2438772	hsa-miR-562	CLIP-seq
MIRT2431216	hsa-miR-563	CLIP-seq
MIRT2572190	hsa-miR-564	CLIP-seq
MIRT2572191	hsa-miR-566	CLIP-seq
MIRT2431217	hsa-miR-573	CLIP-seq
MIRT2685151	hsa-miR-576-5p	CLIP-seq
MIRT2572192	hsa-miR-580	CLIP-seq
MIRT2572193	hsa-miR-583	CLIP-seq
MIRT2572194	hsa-miR-588	CLIP-seq
MIRT2431218	hsa-miR-595	CLIP-seq
MIRT2572195	hsa-miR-604	CLIP-seq
MIRT2572196	hsa-miR-608	CLIP-seq
MIRT1153363	hsa-miR-617	CLIP-seq
MIRT2431219	hsa-miR-625	CLIP-seq
MIRT2572197	hsa-miR-628-5p	CLIP-seq
MIRT2572198	hsa-miR-635	CLIP-seq
MIRT2431220	hsa-miR-644	CLIP-seq
MIRT1153372	hsa-miR-654-5p	CLIP-seq
MIRT2572199	hsa-miR-656	CLIP-seq
MIRT2572200	hsa-miR-661	CLIP-seq
MIRT2685152	hsa-miR-670	CLIP-seq
MIRT2438774	hsa-miR-671-5p	CLIP-seq
MIRT2572201	hsa-miR-760	CLIP-seq
MIRT2438775	hsa-miR-762	CLIP-seq
MIRT2043917	hsa-miR-765	CLIP-seq
MIRT2572202	hsa-miR-766	CLIP-seq
MIRT2572203	hsa-miR-873	CLIP-seq
MIRT2572204	hsa-miR-874	CLIP-seq
MIRT2572205	hsa-miR-875-3p	CLIP-seq
MIRT2431221	hsa-miR-885-3p	CLIP-seq
MIRT2431222	hsa-miR-93	CLIP-seq
MIRT2572206	hsa-miR-942	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
ATF2	Activation	17079470;17258390
ATF3	Repression	11792711;15102941
CEBPE	Unknown	19853299
CREB1	Unknown	10506168
ETS2	Unknown	19939245;22108824
ETV4	Unknown	10506168;15317818
ETV5	Unknown	22968857
EZH2	Activation	21629038
HDAC3	Repression	17079677
HIF1A	Activation	17335808
HIF1A	Repression	17332917;18570733
HOXB7	Activation	21183939
HTATIP2	Repression	19349353
JUN	Activation	15777790
KLF4	Activation	22407433
MSC	Activation	18279606
MZF1	Repression	22846578
NFKB1	Activation	17498959;19303700;20352621
NR4A1	Activation	22551568
PAX6	Unknown	17047041
RELA	Activation	17498959;19303700;20352621
RUNX2	Activation	22641097
SP1	Activation	21469139
SP1	Unknown	10506168;15317818;19853299;21045016
SP3	Unknown	15317818
SRF	Activation	12654640
SSX2	Unknown	15781633
STAT3	Activation	17533737;19284568;20069389
STAT3	Repression	17533737
STAT3	Unknown	16540670
TFAP2A	Unknown	10506168;10589685;19853299;19939245;20145123
TFAP2C	Unknown	19853299
TP53	Activation	10029407;11792711;9343394
TP53	Unknown	19853299;19939245
TWIST1	Activation	20646316
TWIST2	Activation	20646316
YBX1	Unknown	10589685

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001525	Process	Angiogenesis	IEA
GO:0001666	Process	Response to hypoxia	IBA	21873635
GO:0001955	Process	Blood vessel maturation	IEA
GO:0001957	Process	Intramembranous ossification	IEA
GO:0004175	Function	Endopeptidase activity	IDA	23845380
GO:0004222	Function	Metalloendopeptidase activity	IBA	21873635
GO:0004222	Function	Metalloendopeptidase activity	TAS
GO:0004252	Function	Serine-type endopeptidase activity	EXP	17428795
GO:0004252	Function	Serine-type endopeptidase activity	TAS
GO:0005515	Function	Protein binding	IPI	12032297, 20979576, 21441952, 25613181, 25897080, 28106549, 28514442, 32296183, 32814053
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	HDA	20551380
GO:0005615	Component	Extracellular space	IDA	18492766, 24236012, 24784232
GO:0005634	Component	Nucleus	IEA
GO:0005739	Component	Mitochondrion	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0006508	Process	Proteolysis	IDA	15863497
GO:0007566	Process	Embryo implantation	IEA
GO:0008237	Function	Metallopeptidase activity	IDA	24236012
GO:0008270	Function	Zinc ion binding	IEA
GO:0019221	Process	Cytokine-mediated signaling pathway	TAS
GO:0022617	Process	Extracellular matrix disassembly	TAS	24970228
GO:0030017	Component	Sarcomere	IEA
GO:0030198	Process	Extracellular matrix organization	IBA	21873635
GO:0030574	Process	Collagen catabolic process	IBA	21873635
GO:0030574	Process	Collagen catabolic process	TAS
GO:0034614	Process	Cellular response to reactive oxygen species	IEA
GO:0035987	Process	Endodermal cell differentiation	IEP	23154389
GO:0044267	Process	Cellular protein metabolic process	TAS
GO:0048013	Process	Ephrin receptor signaling pathway	TAS
GO:0048771	Process	Tissue remodeling	IBA	21873635
GO:0060325	Process	Face morphogenesis	IEA
GO:0060346	Process	Bone trabecula formation	IEA
GO:0062023	Component	Collagen-containing extracellular matrix	HDA	23979707
GO:0062023	Component	Collagen-containing extracellular matrix	HDA	28327460
GO:0071230	Process	Cellular response to amino acid stimulus	IEA
GO:0071492	Process	Cellular response to UV-A	IDA	31380578
GO:1904645	Process	Response to amyloid-beta	ISS
GO:1904707	Process	Positive regulation of vascular associated smooth muscle cell proliferation	IMP	18667463

Other IDs

• MIM: 120360
• HGNC: 7166
• e!Ensembl: ENSG00000087245

Protein

• UniProt ID: P08253
• Protein name: 72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]
• Protein function: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix
• PDB: 1CK7, 1CXW, 1EAK, 1GEN, 1GXD, 1HOV, 1J7M, 1KS0, 1QIB, 1RTG, 3AYU, 7XGJ, 7XJO, 8H78
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01471	PG_binding_1	43 → 97	Putative peptidoglycan binding domain	Domain
  PF00413	Peptidase_M10	118 → 446	Matrixin	Domain
  PF00040	fn2	233 → 274	Fibronectin type II domain	Domain
  PF00040	fn2	291 → 332	Fibronectin type II domain	Domain
  PF00040	fn2	349 → 390	Fibronectin type II domain	Domain
  PF00045	Hemopexin	475 → 518	Hemopexin	Repeat
  PF00045	Hemopexin	520 → 563	Hemopexin	Repeat
  PF00045	Hemopexin	568 → 615	Hemopexin	Repeat
  PF00045	Hemopexin	617 → 660	Hemopexin	Repeat

• Sequence:

  MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC
  PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
  KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
  GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
  GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
  SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
  ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
  MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQ
  IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
  WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP
  GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
  

• Sequence length: 660