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IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha)

Gene

3419

Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

IDH3A

RP90

15q25.1

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases

Show/Hide all(2)

SNP ID	Visualize variation	Clinical significance	Consequence
rs149862950	T>C	Pathogenic	Missense variant, coding sequence variant
rs756712426	C>A	Pathogenic	Missense variant, coding sequence variant

Show/Hide all(338)

miRTarBase ID	miRNA	Experiments	Reference
MIRT031744	hsa-miR-16-5p	Proteomics	18668040
MIRT459786	hsa-miR-3154	PAR-CLIP	23592263
MIRT459784	hsa-miR-4524b-3p	PAR-CLIP	23592263
MIRT459783	hsa-miR-3125	PAR-CLIP	23592263
MIRT459782	hsa-miR-3916	PAR-CLIP	23592263
MIRT459781	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT459780	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT459779	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT459778	hsa-miR-922	PAR-CLIP	23592263
MIRT459777	hsa-miR-1184	PAR-CLIP	23592263
MIRT459776	hsa-miR-7515	PAR-CLIP	23592263
MIRT459775	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT459774	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT459772	hsa-miR-4784	PAR-CLIP	23592263
MIRT459773	hsa-miR-103a-3p	PAR-CLIP	23592263
MIRT459771	hsa-miR-107	PAR-CLIP	23592263
MIRT459770	hsa-miR-7-5p	PAR-CLIP	23592263
MIRT459769	hsa-miR-4434	PAR-CLIP	23592263
MIRT459768	hsa-miR-4516	PAR-CLIP	23592263
MIRT459767	hsa-miR-5703	PAR-CLIP	23592263
MIRT459766	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT459765	hsa-miR-8085	PAR-CLIP	23592263
MIRT459786	hsa-miR-3154	PAR-CLIP	23592263
MIRT459784	hsa-miR-4524b-3p	PAR-CLIP	23592263
MIRT459783	hsa-miR-3125	PAR-CLIP	23592263
MIRT459782	hsa-miR-3916	PAR-CLIP	23592263
MIRT459781	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT459780	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT459779	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT459778	hsa-miR-922	PAR-CLIP	23592263
MIRT459777	hsa-miR-1184	PAR-CLIP	23592263
MIRT459776	hsa-miR-7515	PAR-CLIP	23592263
MIRT459775	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT459774	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT459772	hsa-miR-4784	PAR-CLIP	23592263
MIRT459773	hsa-miR-103a-3p	PAR-CLIP	23592263
MIRT459771	hsa-miR-107	PAR-CLIP	23592263
MIRT459770	hsa-miR-7-5p	PAR-CLIP	23592263
MIRT459769	hsa-miR-4434	PAR-CLIP	23592263
MIRT459768	hsa-miR-4516	PAR-CLIP	23592263
MIRT459767	hsa-miR-5703	PAR-CLIP	23592263
MIRT459766	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT459765	hsa-miR-8085	PAR-CLIP	23592263
MIRT1059316	hsa-miR-103a	CLIP-seq
MIRT1059317	hsa-miR-1206	CLIP-seq
MIRT1059318	hsa-miR-1915	CLIP-seq
MIRT1059319	hsa-miR-2467-3p	CLIP-seq
MIRT1059320	hsa-miR-3120-5p	CLIP-seq
MIRT1059321	hsa-miR-3171	CLIP-seq
MIRT1059322	hsa-miR-3174	CLIP-seq
MIRT1059323	hsa-miR-3607-3p	CLIP-seq
MIRT1059324	hsa-miR-3647-3p	CLIP-seq
MIRT1059325	hsa-miR-3653	CLIP-seq
MIRT1059326	hsa-miR-3658	CLIP-seq
MIRT1059327	hsa-miR-3659	CLIP-seq
MIRT1059328	hsa-miR-3674	CLIP-seq
MIRT1059329	hsa-miR-3686	CLIP-seq
MIRT1059330	hsa-miR-433	CLIP-seq
MIRT1059331	hsa-miR-4495	CLIP-seq
MIRT1059332	hsa-miR-4641	CLIP-seq
MIRT1059333	hsa-miR-4652-3p	CLIP-seq
MIRT1059334	hsa-miR-4658	CLIP-seq
MIRT1059335	hsa-miR-4699-5p	CLIP-seq
MIRT1059336	hsa-miR-4726-3p	CLIP-seq
MIRT1059337	hsa-miR-4753-3p	CLIP-seq
MIRT1059338	hsa-miR-4762-5p	CLIP-seq
MIRT1059339	hsa-miR-574-5p	CLIP-seq
MIRT1059340	hsa-miR-581	CLIP-seq
MIRT1059341	hsa-miR-593	CLIP-seq
MIRT1059342	hsa-miR-921	CLIP-seq
MIRT2013836	hsa-miR-1324	CLIP-seq
MIRT2013837	hsa-miR-142-3p	CLIP-seq
MIRT2013838	hsa-miR-219-1-3p	CLIP-seq
MIRT2013839	hsa-miR-3065-5p	CLIP-seq
MIRT2013840	hsa-miR-3120-3p	CLIP-seq
MIRT2013841	hsa-miR-323b-5p	CLIP-seq
MIRT1059324	hsa-miR-3647-3p	CLIP-seq
MIRT2013842	hsa-miR-4265	CLIP-seq
MIRT2013843	hsa-miR-4296	CLIP-seq
MIRT2013844	hsa-miR-432	CLIP-seq
MIRT2013845	hsa-miR-4322	CLIP-seq
MIRT2013846	hsa-miR-4696	CLIP-seq
MIRT2013847	hsa-miR-511	CLIP-seq
MIRT2013848	hsa-miR-571	CLIP-seq
MIRT2013849	hsa-miR-587	CLIP-seq
MIRT2013850	hsa-miR-648	CLIP-seq
MIRT2013851	hsa-miR-659	CLIP-seq
MIRT2013852	hsa-miR-9	CLIP-seq
MIRT2246001	hsa-miR-1	CLIP-seq
MIRT2013836	hsa-miR-1324	CLIP-seq
MIRT2246002	hsa-miR-15a	CLIP-seq
MIRT2246003	hsa-miR-15b	CLIP-seq
MIRT2246004	hsa-miR-16	CLIP-seq
MIRT2246005	hsa-miR-195	CLIP-seq
MIRT2246006	hsa-miR-206	CLIP-seq
MIRT2013838	hsa-miR-219-1-3p	CLIP-seq
MIRT2013840	hsa-miR-3120-3p	CLIP-seq
MIRT2246007	hsa-miR-3152-5p	CLIP-seq
MIRT2246008	hsa-miR-3673	CLIP-seq
MIRT2246009	hsa-miR-3925-3p	CLIP-seq
MIRT2246010	hsa-miR-424	CLIP-seq
MIRT2246011	hsa-miR-4423-5p	CLIP-seq
MIRT2246012	hsa-miR-450b-5p	CLIP-seq
MIRT2246013	hsa-miR-4682	CLIP-seq
MIRT2013846	hsa-miR-4696	CLIP-seq
MIRT2246014	hsa-miR-494	CLIP-seq
MIRT2246015	hsa-miR-497	CLIP-seq
MIRT2246016	hsa-miR-507	CLIP-seq
MIRT2246017	hsa-miR-557	CLIP-seq
MIRT2013848	hsa-miR-571	CLIP-seq
MIRT2246018	hsa-miR-613	CLIP-seq
MIRT2246019	hsa-miR-646	CLIP-seq
MIRT2013852	hsa-miR-9	CLIP-seq
MIRT1059317	hsa-miR-1206	CLIP-seq
MIRT2549073	hsa-miR-1225-5p	CLIP-seq
MIRT2549074	hsa-miR-1237	CLIP-seq
MIRT2549075	hsa-miR-1264	CLIP-seq
MIRT2549076	hsa-miR-1277	CLIP-seq
MIRT2549077	hsa-miR-129-3p	CLIP-seq
MIRT2549078	hsa-miR-1322	CLIP-seq
MIRT2013836	hsa-miR-1324	CLIP-seq
MIRT2549079	hsa-miR-149	CLIP-seq
MIRT2246002	hsa-miR-15a	CLIP-seq
MIRT2246003	hsa-miR-15b	CLIP-seq
MIRT2246004	hsa-miR-16	CLIP-seq
MIRT2549080	hsa-miR-1825	CLIP-seq
MIRT2549081	hsa-miR-1827	CLIP-seq
MIRT2549082	hsa-miR-186	CLIP-seq
MIRT2246005	hsa-miR-195	CLIP-seq
MIRT2549083	hsa-miR-199a-5p	CLIP-seq
MIRT2549084	hsa-miR-199b-5p	CLIP-seq
MIRT2549085	hsa-miR-216a	CLIP-seq
MIRT2013838	hsa-miR-219-1-3p	CLIP-seq
MIRT1059319	hsa-miR-2467-3p	CLIP-seq
MIRT2549086	hsa-miR-3064-5p	CLIP-seq
MIRT2549087	hsa-miR-3122	CLIP-seq
MIRT2549088	hsa-miR-3127-3p	CLIP-seq
MIRT1059321	hsa-miR-3171	CLIP-seq
MIRT2549089	hsa-miR-3173-3p	CLIP-seq
MIRT2549090	hsa-miR-3179	CLIP-seq
MIRT2549091	hsa-miR-3180	CLIP-seq
MIRT2549092	hsa-miR-3180-3p	CLIP-seq
MIRT2549093	hsa-miR-3196	CLIP-seq
MIRT2549094	hsa-miR-331-5p	CLIP-seq
MIRT2549095	hsa-miR-338-3p	CLIP-seq
MIRT2549096	hsa-miR-3607-5p	CLIP-seq
MIRT2549097	hsa-miR-3613-3p	CLIP-seq
MIRT2549098	hsa-miR-3616-3p	CLIP-seq
MIRT2549099	hsa-miR-3646	CLIP-seq
MIRT1059324	hsa-miR-3647-3p	CLIP-seq
MIRT1059326	hsa-miR-3658	CLIP-seq
MIRT2549100	hsa-miR-3661	CLIP-seq
MIRT2549101	hsa-miR-3662	CLIP-seq
MIRT1059328	hsa-miR-3674	CLIP-seq
MIRT2549102	hsa-miR-3713	CLIP-seq
MIRT2549103	hsa-miR-3907	CLIP-seq
MIRT2549104	hsa-miR-3913-5p	CLIP-seq
MIRT2549105	hsa-miR-3926	CLIP-seq
MIRT2549106	hsa-miR-3941	CLIP-seq
MIRT2549107	hsa-miR-3942-3p	CLIP-seq
MIRT2549108	hsa-miR-3977	CLIP-seq
MIRT2549109	hsa-miR-3978	CLIP-seq
MIRT2246010	hsa-miR-424	CLIP-seq
MIRT2549110	hsa-miR-4257	CLIP-seq
MIRT2549111	hsa-miR-4317	CLIP-seq
MIRT2013844	hsa-miR-432	CLIP-seq
MIRT2549112	hsa-miR-4323	CLIP-seq
MIRT1059330	hsa-miR-433	CLIP-seq
MIRT2549113	hsa-miR-4436b-3p	CLIP-seq
MIRT2549114	hsa-miR-4457	CLIP-seq
MIRT2549115	hsa-miR-4464	CLIP-seq
MIRT2549116	hsa-miR-4488	CLIP-seq
MIRT1059331	hsa-miR-4495	CLIP-seq
MIRT2549117	hsa-miR-4504	CLIP-seq
MIRT2549118	hsa-miR-450b-3p	CLIP-seq
MIRT2246012	hsa-miR-450b-5p	CLIP-seq
MIRT2549119	hsa-miR-455-3p	CLIP-seq
MIRT2549120	hsa-miR-4639-5p	CLIP-seq
MIRT2549121	hsa-miR-4649-3p	CLIP-seq
MIRT2549122	hsa-miR-466	CLIP-seq
MIRT2549123	hsa-miR-4661-5p	CLIP-seq
MIRT2549124	hsa-miR-4663	CLIP-seq
MIRT2549125	hsa-miR-4667-5p	CLIP-seq
MIRT2549126	hsa-miR-4668-3p	CLIP-seq
MIRT2549127	hsa-miR-4672	CLIP-seq
MIRT2549128	hsa-miR-4678	CLIP-seq
MIRT2549129	hsa-miR-4690-3p	CLIP-seq
MIRT2549130	hsa-miR-4695-5p	CLIP-seq
MIRT2549131	hsa-miR-4697-5p	CLIP-seq
MIRT2549132	hsa-miR-4700-5p	CLIP-seq
MIRT2549133	hsa-miR-4728-3p	CLIP-seq
MIRT2549134	hsa-miR-4731-3p	CLIP-seq
MIRT2549135	hsa-miR-4748	CLIP-seq
MIRT2549136	hsa-miR-4772-5p	CLIP-seq
MIRT2549137	hsa-miR-4794	CLIP-seq
MIRT2549138	hsa-miR-4799-5p	CLIP-seq
MIRT2549139	hsa-miR-4801	CLIP-seq
MIRT2246014	hsa-miR-494	CLIP-seq
MIRT2246015	hsa-miR-497	CLIP-seq
MIRT2246016	hsa-miR-507	CLIP-seq
MIRT2013847	hsa-miR-511	CLIP-seq
MIRT2549140	hsa-miR-513c	CLIP-seq
MIRT2549141	hsa-miR-514b-5p	CLIP-seq
MIRT2549142	hsa-miR-518a-5p	CLIP-seq
MIRT2549143	hsa-miR-520d-5p	CLIP-seq
MIRT2549144	hsa-miR-524-5p	CLIP-seq
MIRT2549145	hsa-miR-527	CLIP-seq
MIRT2549146	hsa-miR-542-3p	CLIP-seq
MIRT2549147	hsa-miR-548c-3p	CLIP-seq
MIRT2549148	hsa-miR-549	CLIP-seq
MIRT2246017	hsa-miR-557	CLIP-seq
MIRT2013848	hsa-miR-571	CLIP-seq
MIRT2549149	hsa-miR-605	CLIP-seq
MIRT2549150	hsa-miR-630	CLIP-seq
MIRT2549151	hsa-miR-631	CLIP-seq
MIRT2549152	hsa-miR-637	CLIP-seq
MIRT2246019	hsa-miR-646	CLIP-seq
MIRT2549153	hsa-miR-758	CLIP-seq
MIRT2549154	hsa-miR-759	CLIP-seq
MIRT2549155	hsa-miR-769-3p	CLIP-seq
MIRT1059317	hsa-miR-1206	CLIP-seq
MIRT2549073	hsa-miR-1225-5p	CLIP-seq
MIRT2549074	hsa-miR-1237	CLIP-seq
MIRT2549075	hsa-miR-1264	CLIP-seq
MIRT2549076	hsa-miR-1277	CLIP-seq
MIRT2549077	hsa-miR-129-3p	CLIP-seq
MIRT2549078	hsa-miR-1322	CLIP-seq
MIRT2013836	hsa-miR-1324	CLIP-seq
MIRT2549079	hsa-miR-149	CLIP-seq
MIRT2246002	hsa-miR-15a	CLIP-seq
MIRT2246003	hsa-miR-15b	CLIP-seq
MIRT2246004	hsa-miR-16	CLIP-seq
MIRT2549080	hsa-miR-1825	CLIP-seq
MIRT2549082	hsa-miR-186	CLIP-seq
MIRT2246005	hsa-miR-195	CLIP-seq
MIRT2549083	hsa-miR-199a-5p	CLIP-seq
MIRT2549084	hsa-miR-199b-5p	CLIP-seq
MIRT2549085	hsa-miR-216a	CLIP-seq
MIRT2013838	hsa-miR-219-1-3p	CLIP-seq
MIRT2549086	hsa-miR-3064-5p	CLIP-seq
MIRT2013839	hsa-miR-3065-5p	CLIP-seq
MIRT2549088	hsa-miR-3127-3p	CLIP-seq
MIRT2682570	hsa-miR-3144-5p	CLIP-seq
MIRT2682571	hsa-miR-3151	CLIP-seq
MIRT2682572	hsa-miR-3153	CLIP-seq
MIRT1059321	hsa-miR-3171	CLIP-seq
MIRT2549089	hsa-miR-3173-3p	CLIP-seq
MIRT2549091	hsa-miR-3180	CLIP-seq
MIRT2549092	hsa-miR-3180-3p	CLIP-seq
MIRT2682573	hsa-miR-3191	CLIP-seq
MIRT2549093	hsa-miR-3196	CLIP-seq
MIRT2682574	hsa-miR-3202	CLIP-seq
MIRT2013841	hsa-miR-323b-5p	CLIP-seq
MIRT2549094	hsa-miR-331-5p	CLIP-seq
MIRT2549095	hsa-miR-338-3p	CLIP-seq
MIRT2682575	hsa-miR-3529	CLIP-seq
MIRT2549096	hsa-miR-3607-5p	CLIP-seq
MIRT2549097	hsa-miR-3613-3p	CLIP-seq
MIRT2549099	hsa-miR-3646	CLIP-seq
MIRT1059324	hsa-miR-3647-3p	CLIP-seq
MIRT1059326	hsa-miR-3658	CLIP-seq
MIRT2549100	hsa-miR-3661	CLIP-seq
MIRT2549101	hsa-miR-3662	CLIP-seq
MIRT1059328	hsa-miR-3674	CLIP-seq
MIRT2549102	hsa-miR-3713	CLIP-seq
MIRT2682576	hsa-miR-379	CLIP-seq
MIRT2549105	hsa-miR-3926	CLIP-seq
MIRT2682577	hsa-miR-3927	CLIP-seq
MIRT2549106	hsa-miR-3941	CLIP-seq
MIRT2549107	hsa-miR-3942-3p	CLIP-seq
MIRT2549108	hsa-miR-3977	CLIP-seq
MIRT2549109	hsa-miR-3978	CLIP-seq
MIRT2246010	hsa-miR-424	CLIP-seq
MIRT2549110	hsa-miR-4257	CLIP-seq
MIRT2013842	hsa-miR-4265	CLIP-seq
MIRT2013843	hsa-miR-4296	CLIP-seq
MIRT2549111	hsa-miR-4317	CLIP-seq
MIRT2013844	hsa-miR-432	CLIP-seq
MIRT2013845	hsa-miR-4322	CLIP-seq
MIRT2549112	hsa-miR-4323	CLIP-seq
MIRT1059330	hsa-miR-433	CLIP-seq
MIRT2682578	hsa-miR-4428	CLIP-seq
MIRT2682579	hsa-miR-4447	CLIP-seq
MIRT2549114	hsa-miR-4457	CLIP-seq
MIRT2549115	hsa-miR-4464	CLIP-seq
MIRT2682580	hsa-miR-4472	CLIP-seq
MIRT2682581	hsa-miR-4476	CLIP-seq
MIRT2549116	hsa-miR-4488	CLIP-seq
MIRT1059331	hsa-miR-4495	CLIP-seq
MIRT2246012	hsa-miR-450b-5p	CLIP-seq
MIRT2549119	hsa-miR-455-3p	CLIP-seq
MIRT2549120	hsa-miR-4639-5p	CLIP-seq
MIRT2682582	hsa-miR-4652-5p	CLIP-seq
MIRT2549122	hsa-miR-466	CLIP-seq
MIRT2549123	hsa-miR-4661-5p	CLIP-seq
MIRT2549124	hsa-miR-4663	CLIP-seq
MIRT2549125	hsa-miR-4667-5p	CLIP-seq
MIRT2549126	hsa-miR-4668-3p	CLIP-seq
MIRT2549127	hsa-miR-4672	CLIP-seq
MIRT2549128	hsa-miR-4678	CLIP-seq
MIRT2549129	hsa-miR-4690-3p	CLIP-seq
MIRT2549130	hsa-miR-4695-5p	CLIP-seq
MIRT2549131	hsa-miR-4697-5p	CLIP-seq
MIRT2549132	hsa-miR-4700-5p	CLIP-seq
MIRT2682583	hsa-miR-4708-5p	CLIP-seq
MIRT2549133	hsa-miR-4728-3p	CLIP-seq
MIRT2549134	hsa-miR-4731-3p	CLIP-seq
MIRT2549135	hsa-miR-4748	CLIP-seq
MIRT2549136	hsa-miR-4772-5p	CLIP-seq
MIRT2549137	hsa-miR-4794	CLIP-seq
MIRT2549138	hsa-miR-4799-5p	CLIP-seq
MIRT2549139	hsa-miR-4801	CLIP-seq
MIRT2682584	hsa-miR-491-5p	CLIP-seq
MIRT2246014	hsa-miR-494	CLIP-seq
MIRT2246015	hsa-miR-497	CLIP-seq
MIRT2246016	hsa-miR-507	CLIP-seq
MIRT2013847	hsa-miR-511	CLIP-seq
MIRT2682585	hsa-miR-512-5p	CLIP-seq
MIRT2549140	hsa-miR-513c	CLIP-seq
MIRT2549141	hsa-miR-514b-5p	CLIP-seq
MIRT2549142	hsa-miR-518a-5p	CLIP-seq
MIRT2549143	hsa-miR-520d-5p	CLIP-seq
MIRT2549144	hsa-miR-524-5p	CLIP-seq
MIRT2549145	hsa-miR-527	CLIP-seq
MIRT2682586	hsa-miR-544b	CLIP-seq
MIRT2549147	hsa-miR-548c-3p	CLIP-seq
MIRT2549148	hsa-miR-549	CLIP-seq
MIRT2246017	hsa-miR-557	CLIP-seq
MIRT2013848	hsa-miR-571	CLIP-seq
MIRT2549149	hsa-miR-605	CLIP-seq
MIRT2549150	hsa-miR-630	CLIP-seq
MIRT2549151	hsa-miR-631	CLIP-seq
MIRT2549152	hsa-miR-637	CLIP-seq
MIRT2246019	hsa-miR-646	CLIP-seq
MIRT2013851	hsa-miR-659	CLIP-seq
MIRT2549153	hsa-miR-758	CLIP-seq
MIRT2549154	hsa-miR-759	CLIP-seq
MIRT2013852	hsa-miR-9	CLIP-seq

Show/Hide all(13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000287	Function	Magnesium ion binding	IDA	28098230
GO:0004449	Function	Isocitrate dehydrogenase (NAD+) activity	IBA	21873635
GO:0004449	Function	Isocitrate dehydrogenase (NAD+) activity	IDA	28098230
GO:0005515	Function	Protein binding	IPI	14555658, 28098230, 28514442
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005739	Component	Mitochondrion	IBA	21873635
GO:0005739	Component	Mitochondrion	IDA
GO:0005759	Component	Mitochondrial matrix	TAS
GO:0005975	Process	Carbohydrate metabolic process	NAS	8833160
GO:0006099	Process	Tricarboxylic acid cycle	IBA	21873635
GO:0006099	Process	Tricarboxylic acid cycle	TAS
GO:0006102	Process	Isocitrate metabolic process	IBA	21873635
GO:0051287	Function	NAD binding	IEA

MIM	HGNC	e!Ensembl
601149	5384	ENSG00000166411

Protein

UniProt ID

P50213

Protein name

Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha)

Protein function

Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma

PDB

5GRE , 5GRF , 5GRH , 5GRI , 5GRL , 5YVT , 6KDE , 6KDF , 6KDY , 6KE3 , 6L57 , 6L59 , 7CE3 , 8GRB , 8GRD , 8GRG , 8GRH , 8GRU , 8GS5

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00180	Iso_dh	33 → 358	Isocitrate/isopropylmalate dehydrogenase	Domain

Sequence

MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP
IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL
YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA
EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV
QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD
MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR
RVKDLD

Sequence length

366

Interactions

View interactions

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