IDH1 (isocitrate dehydrogenase (NADP(+)) 1)

Gene

• Entrez ID: 3417
• Gene name: Isocitrate dehydrogenase (NADP(+)) 1
• Gene symbol: IDH1
• Synonyms: HEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC, PICD
• Chromosome: 2
• Chromosome location: 2q34
• Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs121913499	G>A,C,T	Likely-pathogenic, pathogenic	Coding sequence variant, missense variant
rs121913500	C>A,G,T	Likely-pathogenic, not-provided, pathogenic	Coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005125	hsa-miR-30a-5p	pSILAC	18668040
MIRT017645	hsa-miR-335-5p	Microarray	18185580
MIRT005125	hsa-miR-30a-5p	Proteomics;Other	18668040
MIRT036500	hsa-miR-1226-3p	CLASH	23622248
MIRT054822	hsa-miR-30c-5p	qRT-PCR, Western blot	24623846
MIRT1059154	hsa-miR-1253	CLIP-seq
MIRT1059155	hsa-miR-1255a	CLIP-seq
MIRT1059156	hsa-miR-1255b	CLIP-seq
MIRT1059157	hsa-miR-133a	CLIP-seq
MIRT1059158	hsa-miR-133b	CLIP-seq
MIRT1059159	hsa-miR-137	CLIP-seq
MIRT1059160	hsa-miR-144	CLIP-seq
MIRT1059161	hsa-miR-1539	CLIP-seq
MIRT1059162	hsa-miR-181a	CLIP-seq
MIRT1059163	hsa-miR-181b	CLIP-seq
MIRT1059164	hsa-miR-181c	CLIP-seq
MIRT1059165	hsa-miR-181d	CLIP-seq
MIRT1059166	hsa-miR-1911	CLIP-seq
MIRT1059167	hsa-miR-194	CLIP-seq
MIRT1059168	hsa-miR-1972	CLIP-seq
MIRT1059169	hsa-miR-1976	CLIP-seq
MIRT1059170	hsa-miR-2114	CLIP-seq
MIRT1059171	hsa-miR-219-1-3p	CLIP-seq
MIRT1059172	hsa-miR-25	CLIP-seq
MIRT1059173	hsa-miR-2682	CLIP-seq
MIRT1059174	hsa-miR-28-3p	CLIP-seq
MIRT1059175	hsa-miR-298	CLIP-seq
MIRT1059176	hsa-miR-3146	CLIP-seq
MIRT1059177	hsa-miR-3152-5p	CLIP-seq
MIRT1059178	hsa-miR-3193	CLIP-seq
MIRT1059179	hsa-miR-32	CLIP-seq
MIRT1059180	hsa-miR-323-3p	CLIP-seq
MIRT1059181	hsa-miR-34a	CLIP-seq
MIRT1059182	hsa-miR-34c-5p	CLIP-seq
MIRT1059183	hsa-miR-3609	CLIP-seq
MIRT1059184	hsa-miR-3613-3p	CLIP-seq
MIRT1059185	hsa-miR-3614-5p	CLIP-seq
MIRT1059186	hsa-miR-362-5p	CLIP-seq
MIRT1059187	hsa-miR-363	CLIP-seq
MIRT1059188	hsa-miR-3659	CLIP-seq
MIRT1059189	hsa-miR-3662	CLIP-seq
MIRT1059190	hsa-miR-367	CLIP-seq
MIRT1059191	hsa-miR-3688-5p	CLIP-seq
MIRT1059192	hsa-miR-3714	CLIP-seq
MIRT1059193	hsa-miR-374a	CLIP-seq
MIRT1059194	hsa-miR-374b	CLIP-seq
MIRT1059195	hsa-miR-384	CLIP-seq
MIRT1059196	hsa-miR-3929	CLIP-seq
MIRT1059197	hsa-miR-3978	CLIP-seq
MIRT1059198	hsa-miR-421	CLIP-seq
MIRT1059199	hsa-miR-4251	CLIP-seq
MIRT1059200	hsa-miR-4255	CLIP-seq
MIRT1059201	hsa-miR-4261	CLIP-seq
MIRT1059202	hsa-miR-4262	CLIP-seq
MIRT1059203	hsa-miR-4291	CLIP-seq
MIRT1059204	hsa-miR-4303	CLIP-seq
MIRT1059205	hsa-miR-4325	CLIP-seq
MIRT1059206	hsa-miR-4329	CLIP-seq
MIRT1059207	hsa-miR-4418	CLIP-seq
MIRT1059208	hsa-miR-4419b	CLIP-seq
MIRT1059209	hsa-miR-4433	CLIP-seq
MIRT1059210	hsa-miR-4434	CLIP-seq
MIRT1059211	hsa-miR-4459	CLIP-seq
MIRT1059212	hsa-miR-4474-5p	CLIP-seq
MIRT1059213	hsa-miR-4478	CLIP-seq
MIRT1059214	hsa-miR-449a	CLIP-seq
MIRT1059215	hsa-miR-449b	CLIP-seq
MIRT1059216	hsa-miR-449c	CLIP-seq
MIRT1059217	hsa-miR-4516	CLIP-seq
MIRT1059218	hsa-miR-4530	CLIP-seq
MIRT1059219	hsa-miR-4637	CLIP-seq
MIRT1059220	hsa-miR-4645-3p	CLIP-seq
MIRT1059221	hsa-miR-4658	CLIP-seq
MIRT1059222	hsa-miR-4659a-5p	CLIP-seq
MIRT1059223	hsa-miR-4659b-5p	CLIP-seq
MIRT1059224	hsa-miR-4662a-3p	CLIP-seq
MIRT1059225	hsa-miR-4668-3p	CLIP-seq
MIRT1059226	hsa-miR-4709-5p	CLIP-seq
MIRT1059227	hsa-miR-4716-5p	CLIP-seq
MIRT1059228	hsa-miR-4719	CLIP-seq
MIRT1059229	hsa-miR-4729	CLIP-seq
MIRT1059230	hsa-miR-4747-5p	CLIP-seq
MIRT1059231	hsa-miR-4758-5p	CLIP-seq
MIRT1059232	hsa-miR-4762-3p	CLIP-seq
MIRT1059233	hsa-miR-4768-3p	CLIP-seq
MIRT1059234	hsa-miR-4773	CLIP-seq
MIRT1059235	hsa-miR-4774-3p	CLIP-seq
MIRT1059236	hsa-miR-4776-3p	CLIP-seq
MIRT1059237	hsa-miR-4780	CLIP-seq
MIRT1059238	hsa-miR-483-3p	CLIP-seq
MIRT1059239	hsa-miR-491-3p	CLIP-seq
MIRT1059240	hsa-miR-494	CLIP-seq
MIRT1059241	hsa-miR-500b	CLIP-seq
MIRT1059242	hsa-miR-501-5p	CLIP-seq
MIRT1059243	hsa-miR-509-3-5p	CLIP-seq
MIRT1059244	hsa-miR-509-5p	CLIP-seq
MIRT1059245	hsa-miR-513b	CLIP-seq
MIRT1059246	hsa-miR-520d-5p	CLIP-seq
MIRT1059247	hsa-miR-524-5p	CLIP-seq
MIRT1059248	hsa-miR-539	CLIP-seq
MIRT1059249	hsa-miR-542-3p	CLIP-seq
MIRT1059250	hsa-miR-543	CLIP-seq
MIRT1059251	hsa-miR-545	CLIP-seq
MIRT1059252	hsa-miR-548ah	CLIP-seq
MIRT1059253	hsa-miR-548t	CLIP-seq
MIRT1059254	hsa-miR-571	CLIP-seq
MIRT1059255	hsa-miR-574-5p	CLIP-seq
MIRT1059256	hsa-miR-586	CLIP-seq
MIRT1059257	hsa-miR-623	CLIP-seq
MIRT1059258	hsa-miR-645	CLIP-seq
MIRT1059259	hsa-miR-889	CLIP-seq
MIRT1059260	hsa-miR-890	CLIP-seq
MIRT1059261	hsa-miR-922	CLIP-seq
MIRT1059262	hsa-miR-92a	CLIP-seq
MIRT1059263	hsa-miR-92b	CLIP-seq
MIRT1059154	hsa-miR-1253	CLIP-seq
MIRT1059155	hsa-miR-1255a	CLIP-seq
MIRT1059156	hsa-miR-1255b	CLIP-seq
MIRT1059160	hsa-miR-144	CLIP-seq
MIRT1059162	hsa-miR-181a	CLIP-seq
MIRT1059163	hsa-miR-181b	CLIP-seq
MIRT1059164	hsa-miR-181c	CLIP-seq
MIRT1059165	hsa-miR-181d	CLIP-seq
MIRT2013812	hsa-miR-1914	CLIP-seq
MIRT1059168	hsa-miR-1972	CLIP-seq
MIRT2013813	hsa-miR-23a	CLIP-seq
MIRT2013814	hsa-miR-23b	CLIP-seq
MIRT2013815	hsa-miR-23c	CLIP-seq
MIRT1059173	hsa-miR-2682	CLIP-seq
MIRT1059175	hsa-miR-298	CLIP-seq
MIRT2013816	hsa-miR-30a	CLIP-seq
MIRT2013817	hsa-miR-30b	CLIP-seq
MIRT2013818	hsa-miR-30c	CLIP-seq
MIRT2013819	hsa-miR-30d	CLIP-seq
MIRT2013820	hsa-miR-30e	CLIP-seq
MIRT1059176	hsa-miR-3146	CLIP-seq
MIRT2013821	hsa-miR-3163	CLIP-seq
MIRT2013822	hsa-miR-339-5p	CLIP-seq
MIRT1059181	hsa-miR-34a	CLIP-seq
MIRT1059182	hsa-miR-34c-5p	CLIP-seq
MIRT1059189	hsa-miR-3662	CLIP-seq
MIRT2013823	hsa-miR-3684	CLIP-seq
MIRT1059192	hsa-miR-3714	CLIP-seq
MIRT2013824	hsa-miR-3974	CLIP-seq
MIRT1059197	hsa-miR-3978	CLIP-seq
MIRT2013825	hsa-miR-410	CLIP-seq
MIRT1059198	hsa-miR-421	CLIP-seq
MIRT1059199	hsa-miR-4251	CLIP-seq
MIRT1059200	hsa-miR-4255	CLIP-seq
MIRT1059201	hsa-miR-4261	CLIP-seq
MIRT1059202	hsa-miR-4262	CLIP-seq
MIRT2013826	hsa-miR-4271	CLIP-seq
MIRT1059203	hsa-miR-4291	CLIP-seq
MIRT1059204	hsa-miR-4303	CLIP-seq
MIRT1059205	hsa-miR-4325	CLIP-seq
MIRT1059206	hsa-miR-4329	CLIP-seq
MIRT1059207	hsa-miR-4418	CLIP-seq
MIRT1059209	hsa-miR-4433	CLIP-seq
MIRT1059210	hsa-miR-4434	CLIP-seq
MIRT1059211	hsa-miR-4459	CLIP-seq
MIRT1059212	hsa-miR-4474-5p	CLIP-seq
MIRT2013827	hsa-miR-4495	CLIP-seq
MIRT1059214	hsa-miR-449a	CLIP-seq
MIRT1059215	hsa-miR-449b	CLIP-seq
MIRT1059216	hsa-miR-449c	CLIP-seq
MIRT1059217	hsa-miR-4516	CLIP-seq
MIRT2013828	hsa-miR-4520a-3p	CLIP-seq
MIRT1059218	hsa-miR-4530	CLIP-seq
MIRT1059224	hsa-miR-4662a-3p	CLIP-seq
MIRT1059225	hsa-miR-4668-3p	CLIP-seq
MIRT1059226	hsa-miR-4709-5p	CLIP-seq
MIRT2013829	hsa-miR-4725-3p	CLIP-seq
MIRT1059229	hsa-miR-4729	CLIP-seq
MIRT1059230	hsa-miR-4747-5p	CLIP-seq
MIRT1059232	hsa-miR-4762-3p	CLIP-seq
MIRT1059233	hsa-miR-4768-3p	CLIP-seq
MIRT2013830	hsa-miR-4775	CLIP-seq
MIRT2013831	hsa-miR-4779	CLIP-seq
MIRT2013832	hsa-miR-490-5p	CLIP-seq
MIRT1059240	hsa-miR-494	CLIP-seq
MIRT1059243	hsa-miR-509-3-5p	CLIP-seq
MIRT1059244	hsa-miR-509-5p	CLIP-seq
MIRT1059246	hsa-miR-520d-5p	CLIP-seq
MIRT1059247	hsa-miR-524-5p	CLIP-seq
MIRT1059248	hsa-miR-539	CLIP-seq
MIRT1059250	hsa-miR-543	CLIP-seq
MIRT1059251	hsa-miR-545	CLIP-seq
MIRT2013833	hsa-miR-590-3p	CLIP-seq
MIRT2013834	hsa-miR-649	CLIP-seq
MIRT2013835	hsa-miR-670	CLIP-seq
MIRT1059259	hsa-miR-889	CLIP-seq
MIRT1059261	hsa-miR-922	CLIP-seq
MIRT1059155	hsa-miR-1255a	CLIP-seq
MIRT1059156	hsa-miR-1255b	CLIP-seq
MIRT2245975	hsa-miR-1303	CLIP-seq
MIRT1059157	hsa-miR-133a	CLIP-seq
MIRT1059158	hsa-miR-133b	CLIP-seq
MIRT1059159	hsa-miR-137	CLIP-seq
MIRT2245976	hsa-miR-145	CLIP-seq
MIRT2245977	hsa-miR-155	CLIP-seq
MIRT2245978	hsa-miR-185	CLIP-seq
MIRT1059166	hsa-miR-1911	CLIP-seq
MIRT2013812	hsa-miR-1914	CLIP-seq
MIRT1059167	hsa-miR-194	CLIP-seq
MIRT2245979	hsa-miR-196a	CLIP-seq
MIRT2245980	hsa-miR-196b	CLIP-seq
MIRT2245981	hsa-miR-19a	CLIP-seq
MIRT2245982	hsa-miR-19b	CLIP-seq
MIRT1059171	hsa-miR-219-1-3p	CLIP-seq
MIRT1059172	hsa-miR-25	CLIP-seq
MIRT1059173	hsa-miR-2682	CLIP-seq
MIRT1059175	hsa-miR-298	CLIP-seq
MIRT2013816	hsa-miR-30a	CLIP-seq
MIRT2013817	hsa-miR-30b	CLIP-seq
MIRT2013818	hsa-miR-30c	CLIP-seq
MIRT2013819	hsa-miR-30d	CLIP-seq
MIRT2013820	hsa-miR-30e	CLIP-seq
MIRT1059176	hsa-miR-3146	CLIP-seq
MIRT2013821	hsa-miR-3163	CLIP-seq
MIRT1059179	hsa-miR-32	CLIP-seq
MIRT1059180	hsa-miR-323-3p	CLIP-seq
MIRT2013822	hsa-miR-339-5p	CLIP-seq
MIRT1059181	hsa-miR-34a	CLIP-seq
MIRT1059182	hsa-miR-34c-5p	CLIP-seq
MIRT2245983	hsa-miR-3607-5p	CLIP-seq
MIRT1059183	hsa-miR-3609	CLIP-seq
MIRT1059184	hsa-miR-3613-3p	CLIP-seq
MIRT1059185	hsa-miR-3614-5p	CLIP-seq
MIRT1059186	hsa-miR-362-5p	CLIP-seq
MIRT1059187	hsa-miR-363	CLIP-seq
MIRT1059188	hsa-miR-3659	CLIP-seq
MIRT1059190	hsa-miR-367	CLIP-seq
MIRT1059191	hsa-miR-3688-5p	CLIP-seq
MIRT2245984	hsa-miR-369-3p	CLIP-seq
MIRT1059192	hsa-miR-3714	CLIP-seq
MIRT1059193	hsa-miR-374a	CLIP-seq
MIRT1059194	hsa-miR-374b	CLIP-seq
MIRT2013824	hsa-miR-3974	CLIP-seq
MIRT2013825	hsa-miR-410	CLIP-seq
MIRT2245985	hsa-miR-425	CLIP-seq
MIRT2013826	hsa-miR-4271	CLIP-seq
MIRT2245986	hsa-miR-4306	CLIP-seq
MIRT1059205	hsa-miR-4325	CLIP-seq
MIRT1059211	hsa-miR-4459	CLIP-seq
MIRT2013827	hsa-miR-4495	CLIP-seq
MIRT1059214	hsa-miR-449a	CLIP-seq
MIRT1059215	hsa-miR-449b	CLIP-seq
MIRT1059216	hsa-miR-449c	CLIP-seq
MIRT2013828	hsa-miR-4520a-3p	CLIP-seq
MIRT1059218	hsa-miR-4530	CLIP-seq
MIRT1059219	hsa-miR-4637	CLIP-seq
MIRT2245987	hsa-miR-4644	CLIP-seq
MIRT1059220	hsa-miR-4645-3p	CLIP-seq
MIRT1059221	hsa-miR-4658	CLIP-seq
MIRT1059222	hsa-miR-4659a-5p	CLIP-seq
MIRT1059223	hsa-miR-4659b-5p	CLIP-seq
MIRT2245988	hsa-miR-4694-3p	CLIP-seq
MIRT1059227	hsa-miR-4716-5p	CLIP-seq
MIRT1059228	hsa-miR-4719	CLIP-seq
MIRT2013829	hsa-miR-4725-3p	CLIP-seq
MIRT1059229	hsa-miR-4729	CLIP-seq
MIRT1059230	hsa-miR-4747-5p	CLIP-seq
MIRT1059231	hsa-miR-4758-5p	CLIP-seq
MIRT2245989	hsa-miR-4777-3p	CLIP-seq
MIRT2013831	hsa-miR-4779	CLIP-seq
MIRT1059238	hsa-miR-483-3p	CLIP-seq
MIRT2013832	hsa-miR-490-5p	CLIP-seq
MIRT1059241	hsa-miR-500b	CLIP-seq
MIRT1059242	hsa-miR-501-5p	CLIP-seq
MIRT1059246	hsa-miR-520d-5p	CLIP-seq
MIRT1059247	hsa-miR-524-5p	CLIP-seq
MIRT1059248	hsa-miR-539	CLIP-seq
MIRT1059249	hsa-miR-542-3p	CLIP-seq
MIRT1059252	hsa-miR-548ah	CLIP-seq
MIRT1059253	hsa-miR-548t	CLIP-seq
MIRT1059254	hsa-miR-571	CLIP-seq
MIRT1059255	hsa-miR-574-5p	CLIP-seq
MIRT2013834	hsa-miR-649	CLIP-seq
MIRT2013835	hsa-miR-670	CLIP-seq
MIRT1059260	hsa-miR-890	CLIP-seq
MIRT1059261	hsa-miR-922	CLIP-seq
MIRT1059262	hsa-miR-92a	CLIP-seq
MIRT1059263	hsa-miR-92b	CLIP-seq
MIRT1059159	hsa-miR-137	CLIP-seq
MIRT2013812	hsa-miR-1914	CLIP-seq
MIRT1059171	hsa-miR-219-1-3p	CLIP-seq
MIRT1059180	hsa-miR-323-3p	CLIP-seq
MIRT2013822	hsa-miR-339-5p	CLIP-seq
MIRT2013824	hsa-miR-3974	CLIP-seq
MIRT1059198	hsa-miR-421	CLIP-seq
MIRT1059205	hsa-miR-4325	CLIP-seq
MIRT1059238	hsa-miR-483-3p	CLIP-seq
MIRT2013832	hsa-miR-490-5p	CLIP-seq
MIRT1059254	hsa-miR-571	CLIP-seq
MIRT2013835	hsa-miR-670	CLIP-seq
MIRT2245976	hsa-miR-145	CLIP-seq
MIRT2245977	hsa-miR-155	CLIP-seq
MIRT2245981	hsa-miR-19a	CLIP-seq
MIRT2245982	hsa-miR-19b	CLIP-seq
MIRT2245983	hsa-miR-3607-5p	CLIP-seq
MIRT2013832	hsa-miR-490-5p	CLIP-seq
MIRT2549058	hsa-miR-1321	CLIP-seq
MIRT1059157	hsa-miR-133a	CLIP-seq
MIRT1059158	hsa-miR-133b	CLIP-seq
MIRT2245976	hsa-miR-145	CLIP-seq
MIRT2245977	hsa-miR-155	CLIP-seq
MIRT2013812	hsa-miR-1914	CLIP-seq
MIRT2245981	hsa-miR-19a	CLIP-seq
MIRT2245982	hsa-miR-19b	CLIP-seq
MIRT2549059	hsa-miR-200b	CLIP-seq
MIRT2549060	hsa-miR-200c	CLIP-seq
MIRT1059173	hsa-miR-2682	CLIP-seq
MIRT2549061	hsa-miR-2909	CLIP-seq
MIRT2549062	hsa-miR-3162-5p	CLIP-seq
MIRT2013822	hsa-miR-339-5p	CLIP-seq
MIRT1059181	hsa-miR-34a	CLIP-seq
MIRT1059182	hsa-miR-34c-5p	CLIP-seq
MIRT2245983	hsa-miR-3607-5p	CLIP-seq
MIRT1059192	hsa-miR-3714	CLIP-seq
MIRT1059193	hsa-miR-374a	CLIP-seq
MIRT1059194	hsa-miR-374b	CLIP-seq
MIRT1059195	hsa-miR-384	CLIP-seq
MIRT1059196	hsa-miR-3929	CLIP-seq
MIRT2549063	hsa-miR-3942-5p	CLIP-seq
MIRT2013824	hsa-miR-3974	CLIP-seq
MIRT1059198	hsa-miR-421	CLIP-seq
MIRT2013826	hsa-miR-4271	CLIP-seq
MIRT2549064	hsa-miR-429	CLIP-seq
MIRT1059203	hsa-miR-4291	CLIP-seq
MIRT2549065	hsa-miR-4318	CLIP-seq
MIRT1059207	hsa-miR-4418	CLIP-seq
MIRT1059208	hsa-miR-4419b	CLIP-seq
MIRT1059211	hsa-miR-4459	CLIP-seq
MIRT2549066	hsa-miR-4474-3p	CLIP-seq
MIRT1059213	hsa-miR-4478	CLIP-seq
MIRT2549067	hsa-miR-448	CLIP-seq
MIRT1059214	hsa-miR-449a	CLIP-seq
MIRT1059215	hsa-miR-449b	CLIP-seq
MIRT1059216	hsa-miR-449c	CLIP-seq
MIRT2013828	hsa-miR-4520a-3p	CLIP-seq
MIRT2549068	hsa-miR-4693-5p	CLIP-seq
MIRT2549069	hsa-miR-4703-5p	CLIP-seq
MIRT1059228	hsa-miR-4719	CLIP-seq
MIRT2013829	hsa-miR-4725-3p	CLIP-seq
MIRT1059229	hsa-miR-4729	CLIP-seq
MIRT2549070	hsa-miR-4739	CLIP-seq
MIRT1059230	hsa-miR-4747-5p	CLIP-seq
MIRT2549071	hsa-miR-4756-5p	CLIP-seq
MIRT1059234	hsa-miR-4773	CLIP-seq
MIRT2245989	hsa-miR-4777-3p	CLIP-seq
MIRT2013831	hsa-miR-4779	CLIP-seq
MIRT2013832	hsa-miR-490-5p	CLIP-seq
MIRT1059239	hsa-miR-491-3p	CLIP-seq
MIRT1059243	hsa-miR-509-3-5p	CLIP-seq
MIRT1059244	hsa-miR-509-5p	CLIP-seq
MIRT1059248	hsa-miR-539	CLIP-seq
MIRT1059251	hsa-miR-545	CLIP-seq
MIRT1059256	hsa-miR-586	CLIP-seq
MIRT1059258	hsa-miR-645	CLIP-seq
MIRT2013835	hsa-miR-670	CLIP-seq
MIRT2549072	hsa-miR-892a	CLIP-seq
MIRT2549058	hsa-miR-1321	CLIP-seq
MIRT1059157	hsa-miR-133a	CLIP-seq
MIRT1059158	hsa-miR-133b	CLIP-seq
MIRT2245976	hsa-miR-145	CLIP-seq
MIRT2245977	hsa-miR-155	CLIP-seq
MIRT2013812	hsa-miR-1914	CLIP-seq
MIRT2245981	hsa-miR-19a	CLIP-seq
MIRT2245982	hsa-miR-19b	CLIP-seq
MIRT2549059	hsa-miR-200b	CLIP-seq
MIRT2549060	hsa-miR-200c	CLIP-seq
MIRT1059173	hsa-miR-2682	CLIP-seq
MIRT2549061	hsa-miR-2909	CLIP-seq
MIRT2549062	hsa-miR-3162-5p	CLIP-seq
MIRT2013822	hsa-miR-339-5p	CLIP-seq
MIRT1059181	hsa-miR-34a	CLIP-seq
MIRT1059182	hsa-miR-34c-5p	CLIP-seq
MIRT2245983	hsa-miR-3607-5p	CLIP-seq
MIRT1059192	hsa-miR-3714	CLIP-seq
MIRT1059193	hsa-miR-374a	CLIP-seq
MIRT1059194	hsa-miR-374b	CLIP-seq
MIRT2549063	hsa-miR-3942-5p	CLIP-seq
MIRT2013824	hsa-miR-3974	CLIP-seq
MIRT1059198	hsa-miR-421	CLIP-seq
MIRT2013826	hsa-miR-4271	CLIP-seq
MIRT2549064	hsa-miR-429	CLIP-seq
MIRT2549065	hsa-miR-4318	CLIP-seq
MIRT1059207	hsa-miR-4418	CLIP-seq
MIRT1059211	hsa-miR-4459	CLIP-seq
MIRT2549066	hsa-miR-4474-3p	CLIP-seq
MIRT2549067	hsa-miR-448	CLIP-seq
MIRT1059214	hsa-miR-449a	CLIP-seq
MIRT1059215	hsa-miR-449b	CLIP-seq
MIRT1059216	hsa-miR-449c	CLIP-seq
MIRT2013828	hsa-miR-4520a-3p	CLIP-seq
MIRT2549068	hsa-miR-4693-5p	CLIP-seq
MIRT2549069	hsa-miR-4703-5p	CLIP-seq
MIRT1059228	hsa-miR-4719	CLIP-seq
MIRT2013829	hsa-miR-4725-3p	CLIP-seq
MIRT1059229	hsa-miR-4729	CLIP-seq
MIRT2549070	hsa-miR-4739	CLIP-seq
MIRT1059230	hsa-miR-4747-5p	CLIP-seq
MIRT2549071	hsa-miR-4756-5p	CLIP-seq
MIRT1059234	hsa-miR-4773	CLIP-seq
MIRT2245989	hsa-miR-4777-3p	CLIP-seq
MIRT2013831	hsa-miR-4779	CLIP-seq
MIRT2013832	hsa-miR-490-5p	CLIP-seq
MIRT1059239	hsa-miR-491-3p	CLIP-seq
MIRT1059243	hsa-miR-509-3-5p	CLIP-seq
MIRT1059244	hsa-miR-509-5p	CLIP-seq
MIRT1059248	hsa-miR-539	CLIP-seq
MIRT1059256	hsa-miR-586	CLIP-seq
MIRT2013835	hsa-miR-670	CLIP-seq
MIRT2549072	hsa-miR-892a	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000287	Function	Magnesium ion binding	IDA	19935646
GO:0004450	Function	Isocitrate dehydrogenase (NADP+) activity	IBA	21873635
GO:0004450	Function	Isocitrate dehydrogenase (NADP+) activity	IDA	10521434, 19935646, 20171178
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005576	Component	Extracellular region	TAS
GO:0005737	Component	Cytoplasm	IDA
GO:0005739	Component	Mitochondrion	IBA	21873635
GO:0005777	Component	Peroxisome	IBA	21873635
GO:0005777	Component	Peroxisome	IDA	10521434
GO:0005782	Component	Peroxisomal matrix	TAS
GO:0005829	Component	Cytosol	IBA	21873635
GO:0005829	Component	Cytosol	IDA	10521434
GO:0005829	Component	Cytosol	TAS
GO:0006097	Process	Glyoxylate cycle	IEA
GO:0006099	Process	Tricarboxylic acid cycle	IEA
GO:0006102	Process	Isocitrate metabolic process	IBA	21873635
GO:0006102	Process	Isocitrate metabolic process	IDA	10521434, 19935646, 20171178
GO:0006103	Process	2-oxoglutarate metabolic process	IDA	19935646
GO:0006103	Process	2-oxoglutarate metabolic process	TAS
GO:0006625	Process	Protein targeting to peroxisome	TAS
GO:0006739	Process	NADP metabolic process	IBA	21873635
GO:0006740	Process	NADPH regeneration	TAS
GO:0006749	Process	Glutathione metabolic process	IEA
GO:0006979	Process	Response to oxidative stress	IEA
GO:0008585	Process	Female gonad development	IEA
GO:0034774	Component	Secretory granule lumen	TAS
GO:0042802	Function	Identical protein binding	IPI	19935646, 21516116, 26436839
GO:0042803	Function	Protein homodimerization activity	IPI	19935646
GO:0043312	Process	Neutrophil degranulation	TAS
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0048545	Process	Response to steroid hormone	IEA
GO:0050661	Function	NADP binding	IEA
GO:0051287	Function	NAD binding	IEA
GO:0060696	Process	Regulation of phospholipid catabolic process	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 23533145
GO:0071071	Process	Regulation of phospholipid biosynthetic process	IEA
GO:1904724	Component	Tertiary granule lumen	TAS
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS

Other IDs

• MIM: 147700
• HGNC: 5382
• e!Ensembl: ENSG00000138413

Protein

• UniProt ID: O75874
• Protein name: Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (IDH1) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDPc) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
• Protein function: Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase (PubMed:10521434, PubMed:19935646). Plays
• PDB: 1T09, 1T0L, 3INM, 3MAP, 3MAR, 3MAS, 4I3K, 4I3L, 4KZO, 4L03, 4L04, 4L06, 4UMX, 4UMY, 4XRX, 4XS3, 5DE1, 5GIR, 5K10, 5K11, 5L57, 5L58, 5LGE, 5SUN, 5SVF, 5TQH, 5YFM, 5YFN, 6ADG, 6B0Z, 6BKX, 6BKY, 6BKZ, 6BL0, 6BL1, 6BL2, 6IO0, 6O2Y, 6O2Z, 6PAY, 6Q6F, 6U4J, 6VEI, 6VG0, 7PJM, 7PJN, 8BAY, 8HB9, 8T7D, 8T7N, 8T7O
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00180	Iso_dh	9 → 401	Isocitrate/isopropylmalate dehydrogenase	Domain

• Sequence:

  MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
  AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
  VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
  GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
  AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
  KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
  EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL

• Sequence length: 414