Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
2773 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
G protein subunit alpha i3 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
GNAI3 |
SynonymsGene synonyms aliases
|
87U6, ARCND1, ARCODS, HG1A |
ChromosomeChromosome number
|
1 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
1p13.3 |
SummarySummary of gene provided in NCBI Entrez Gene.
|
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alph |
SNPsSNP information provided by dbSNP.
|
SNP ID |
Visualize variation |
Clinical significance |
Consequence |
rs387907178 |
G>A,C |
Pathogenic |
Coding sequence variant, missense variant |
rs397514768 |
C>A |
Pathogenic |
Coding sequence variant, missense variant |
|
miRNAmiRNA information provided by mirtarbase database.
|
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
P08754 |
Protein name |
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3) |
Protein function |
Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates |
PDB |
2IHB
,
2ODE
,
2V4Z
,
4G5O
,
4G5R
,
4G5S
,
7E9H
,
7KH0
,
7RA3
,
7RGP
,
7T10
,
7T11
,
7X6I
,
8GVX
,
8JD6
,
8K9L
,
8OY1
,
8SZH
,
8SZI
,
8WGB
,
9AVL
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00503 |
G-alpha |
13 → 343 |
G-protein alpha subunit |
Domain |
|
Sequence |
|
Sequence length |
354 |
Interactions |
View interactions |