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GLUL (glutamate-ammonia ligase)

Gene

2752

Glutamate-ammonia ligase

GLUL

DEE116, GLNS, GS, PIG43, PIG59

1q25.3

The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base home

Show/Hide all(3)

SNP ID	Visualize variation	Clinical significance	Consequence
rs80358214	G>A,T	Pathogenic	Missense variant, coding sequence variant
rs80358215	G>A	Pathogenic	Missense variant, coding sequence variant
rs1131691970	T>A	Likely-pathogenic	Initiator codon variant, missense variant

Show/Hide all(590)

miRTarBase ID	miRNA	Experiments	Reference
MIRT004021	hsa-miR-29a-3p	Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	19951903
MIRT004021	hsa-miR-29a-3p	Immunoblot, Luciferase reporter assay, Microarray, qRT-PCR	19951903
MIRT021141	hsa-miR-186-5p	Sequencing	20371350
MIRT025018	hsa-miR-183-5p	Sequencing	20371350
MIRT030540	hsa-miR-24-3p	Sequencing	20371350
MIRT052399	hsa-let-7a-5p	CLASH	23622248
MIRT052399	hsa-let-7a-5p	CLASH	23622248
MIRT051664	hsa-let-7e-5p	CLASH	23622248
MIRT051362	hsa-let-7f-5p	CLASH	23622248
MIRT048155	hsa-miR-196a-5p	CLASH	23622248
MIRT045626	hsa-miR-149-5p	CLASH	23622248
MIRT045330	hsa-miR-185-5p	CLASH	23622248
MIRT044856	hsa-miR-320a	CLASH	23622248
MIRT041957	hsa-miR-484	CLASH	23622248
MIRT040016	hsa-miR-615-3p	CLASH	23622248
MIRT038640	hsa-miR-125a-3p	CLASH	23622248
MIRT038394	hsa-miR-296-3p	CLASH	23622248
MIRT038153	hsa-miR-423-5p	CLASH	23622248
MIRT037273	hsa-miR-877-5p	CLASH	23622248
MIRT036966	hsa-miR-877-3p	CLASH	23622248
MIRT036638	hsa-miR-937-3p	CLASH	23622248
MIRT036244	hsa-miR-320b	CLASH	23622248
MIRT710654	hsa-miR-6514-5p	HITS-CLIP	19536157
MIRT710653	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT710652	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT710651	hsa-miR-143-3p	HITS-CLIP	19536157
MIRT710650	hsa-miR-4770	HITS-CLIP	19536157
MIRT710649	hsa-miR-6088	HITS-CLIP	19536157
MIRT710648	hsa-miR-4708-5p	HITS-CLIP	19536157
MIRT710647	hsa-miR-1273f	HITS-CLIP	19536157
MIRT710646	hsa-miR-4534	HITS-CLIP	19536157
MIRT710645	hsa-miR-8082	HITS-CLIP	19536157
MIRT710644	hsa-miR-4653-3p	HITS-CLIP	19536157
MIRT710643	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT710642	hsa-miR-744-3p	HITS-CLIP	19536157
MIRT710641	hsa-miR-4755-5p	HITS-CLIP	19536157
MIRT710640	hsa-miR-5006-3p	HITS-CLIP	19536157
MIRT710639	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT710638	hsa-miR-8055	HITS-CLIP	19536157
MIRT710637	hsa-miR-129-5p	HITS-CLIP	19536157
MIRT688092	hsa-miR-495-5p	HITS-CLIP	23313552
MIRT688091	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT688090	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT688089	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT688088	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT688087	hsa-miR-940	HITS-CLIP	23313552
MIRT688086	hsa-miR-3929	HITS-CLIP	23313552
MIRT688085	hsa-miR-4419b	HITS-CLIP	23313552
MIRT688084	hsa-miR-4478	HITS-CLIP	23313552
MIRT688083	hsa-miR-1298-3p	HITS-CLIP	23313552
MIRT688082	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT688081	hsa-miR-204-3p	HITS-CLIP	23313552
MIRT688080	hsa-miR-4646-5p	HITS-CLIP	23313552
MIRT523532	hsa-miR-3192-5p	HITS-CLIP	23313552
MIRT688079	hsa-miR-1827	HITS-CLIP	23313552
MIRT688078	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT688077	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT688076	hsa-miR-298	HITS-CLIP	23313552
MIRT688075	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT688074	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT688073	hsa-miR-3612	HITS-CLIP	23313552
MIRT688072	hsa-miR-650	HITS-CLIP	23313552
MIRT688071	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT688070	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT688069	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT688068	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT688067	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT688066	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT688065	hsa-miR-4314	HITS-CLIP	23313552
MIRT688064	hsa-miR-455-3p	HITS-CLIP	23313552
MIRT688063	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT688062	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT688061	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT688060	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT688059	hsa-miR-3689c	HITS-CLIP	23313552
MIRT688058	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT688057	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT688056	hsa-miR-6516-5p	HITS-CLIP	23313552
MIRT688055	hsa-miR-665	HITS-CLIP	23313552
MIRT688054	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT688053	hsa-miR-383-5p	HITS-CLIP	23313552
MIRT688052	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT688051	hsa-miR-4459	HITS-CLIP	23313552
MIRT688050	hsa-miR-4433a-3p	HITS-CLIP	23313552
MIRT688049	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT688048	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT688047	hsa-miR-4772-5p	HITS-CLIP	23313552
MIRT688046	hsa-miR-4683	HITS-CLIP	23313552
MIRT688045	hsa-miR-3926	HITS-CLIP	23313552
MIRT523524	hsa-miR-6878-5p	HITS-CLIP	23313552
MIRT523523	hsa-miR-6731-5p	HITS-CLIP	23313552
MIRT523522	hsa-miR-8085	HITS-CLIP	23313552
MIRT688044	hsa-miR-548s	HITS-CLIP	23313552
MIRT523512	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT523511	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT523510	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT663730	hsa-miR-4418	HITS-CLIP	23824327
MIRT663729	hsa-miR-509-3-5p	HITS-CLIP	23824327
MIRT663728	hsa-miR-509-5p	HITS-CLIP	23824327
MIRT663727	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT663726	hsa-miR-1184	HITS-CLIP	23824327
MIRT663725	hsa-miR-4660	HITS-CLIP	23824327
MIRT663724	hsa-miR-181b-2-3p	HITS-CLIP	23824327
MIRT663723	hsa-miR-181b-3p	HITS-CLIP	23824327
MIRT663722	hsa-miR-4420	HITS-CLIP	23824327
MIRT663721	hsa-miR-653-3p	HITS-CLIP	23824327
MIRT663720	hsa-miR-1301-3p	HITS-CLIP	23824327
MIRT663719	hsa-miR-5047	HITS-CLIP	23824327
MIRT523535	hsa-miR-4511	PAR-CLIP	23446348
MIRT523534	hsa-miR-4716-3p	PAR-CLIP	23446348
MIRT523533	hsa-miR-6794-5p	PAR-CLIP	23446348
MIRT523532	hsa-miR-3192-5p	PAR-CLIP	23446348
MIRT523531	hsa-miR-3185	PAR-CLIP	23446348
MIRT523530	hsa-miR-549a	PAR-CLIP	23446348
MIRT523529	hsa-miR-4481	PAR-CLIP	23446348
MIRT523528	hsa-miR-4745-5p	PAR-CLIP	23446348
MIRT523527	hsa-miR-571	PAR-CLIP	23446348
MIRT523526	hsa-miR-504-3p	PAR-CLIP	23446348
MIRT523525	hsa-miR-122-5p	PAR-CLIP	23446348
MIRT523524	hsa-miR-6878-5p	PAR-CLIP	23446348
MIRT523523	hsa-miR-6731-5p	PAR-CLIP	23446348
MIRT523522	hsa-miR-8085	PAR-CLIP	23446348
MIRT523521	hsa-miR-5187-5p	PAR-CLIP	23446348
MIRT523520	hsa-miR-4271	PAR-CLIP	23446348
MIRT523519	hsa-miR-4725-3p	PAR-CLIP	23446348
MIRT523518	hsa-miR-6780b-5p	PAR-CLIP	23446348
MIRT523517	hsa-miR-625-5p	PAR-CLIP	23446348
MIRT523516	hsa-miR-4654	PAR-CLIP	23446348
MIRT523515	hsa-miR-4769-5p	PAR-CLIP	23446348
MIRT523514	hsa-miR-3198	PAR-CLIP	23446348
MIRT523513	hsa-miR-4309	PAR-CLIP	23446348
MIRT523512	hsa-miR-30c-1-3p	PAR-CLIP	23446348
MIRT523511	hsa-miR-30c-2-3p	PAR-CLIP	23446348
MIRT523510	hsa-miR-6788-5p	PAR-CLIP	23446348
MIRT523509	hsa-miR-6728-5p	PAR-CLIP	23446348
MIRT710654	hsa-miR-6514-5p	HITS-CLIP	19536157
MIRT710653	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT710652	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT710651	hsa-miR-143-3p	HITS-CLIP	19536157
MIRT710650	hsa-miR-4770	HITS-CLIP	19536157
MIRT710649	hsa-miR-6088	HITS-CLIP	19536157
MIRT710648	hsa-miR-4708-5p	HITS-CLIP	19536157
MIRT710647	hsa-miR-1273f	HITS-CLIP	19536157
MIRT710646	hsa-miR-4534	HITS-CLIP	19536157
MIRT710645	hsa-miR-8082	HITS-CLIP	19536157
MIRT710644	hsa-miR-4653-3p	HITS-CLIP	19536157
MIRT710643	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT710642	hsa-miR-744-3p	HITS-CLIP	19536157
MIRT710641	hsa-miR-4755-5p	HITS-CLIP	19536157
MIRT710640	hsa-miR-5006-3p	HITS-CLIP	19536157
MIRT710639	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT710638	hsa-miR-8055	HITS-CLIP	19536157
MIRT710637	hsa-miR-129-5p	HITS-CLIP	19536157
MIRT688092	hsa-miR-495-5p	HITS-CLIP	23313552
MIRT688091	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT688090	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT688089	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT688088	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT688087	hsa-miR-940	HITS-CLIP	23313552
MIRT688086	hsa-miR-3929	HITS-CLIP	23313552
MIRT688085	hsa-miR-4419b	HITS-CLIP	23313552
MIRT688084	hsa-miR-4478	HITS-CLIP	23313552
MIRT688083	hsa-miR-1298-3p	HITS-CLIP	23313552
MIRT688082	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT688081	hsa-miR-204-3p	HITS-CLIP	23313552
MIRT688080	hsa-miR-4646-5p	HITS-CLIP	23313552
MIRT523532	hsa-miR-3192-5p	HITS-CLIP	23313552
MIRT688079	hsa-miR-1827	HITS-CLIP	23313552
MIRT688078	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT688077	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT688076	hsa-miR-298	HITS-CLIP	23313552
MIRT688075	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT688074	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT688073	hsa-miR-3612	HITS-CLIP	23313552
MIRT688072	hsa-miR-650	HITS-CLIP	23313552
MIRT688071	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT688070	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT688069	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT688068	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT688067	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT688066	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT688065	hsa-miR-4314	HITS-CLIP	23313552
MIRT688064	hsa-miR-455-3p	HITS-CLIP	23313552
MIRT688063	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT688062	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT688061	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT688060	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT688059	hsa-miR-3689c	HITS-CLIP	23313552
MIRT688058	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT688057	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT688056	hsa-miR-6516-5p	HITS-CLIP	23313552
MIRT688055	hsa-miR-665	HITS-CLIP	23313552
MIRT688054	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT688053	hsa-miR-383-5p	HITS-CLIP	23313552
MIRT688052	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT688051	hsa-miR-4459	HITS-CLIP	23313552
MIRT688050	hsa-miR-4433a-3p	HITS-CLIP	23313552
MIRT688049	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT688048	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT688047	hsa-miR-4772-5p	HITS-CLIP	23313552
MIRT688046	hsa-miR-4683	HITS-CLIP	23313552
MIRT688045	hsa-miR-3926	HITS-CLIP	23313552
MIRT523524	hsa-miR-6878-5p	HITS-CLIP	23313552
MIRT523523	hsa-miR-6731-5p	HITS-CLIP	23313552
MIRT523522	hsa-miR-8085	HITS-CLIP	23313552
MIRT688044	hsa-miR-548s	HITS-CLIP	23313552
MIRT523512	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT523511	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT523510	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT663730	hsa-miR-4418	HITS-CLIP	23824327
MIRT663729	hsa-miR-509-3-5p	HITS-CLIP	23824327
MIRT663728	hsa-miR-509-5p	HITS-CLIP	23824327
MIRT663727	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT663726	hsa-miR-1184	HITS-CLIP	23824327
MIRT663725	hsa-miR-4660	HITS-CLIP	23824327
MIRT663724	hsa-miR-181b-2-3p	HITS-CLIP	23824327
MIRT663723	hsa-miR-181b-3p	HITS-CLIP	23824327
MIRT663722	hsa-miR-4420	HITS-CLIP	23824327
MIRT663721	hsa-miR-653-3p	HITS-CLIP	23824327
MIRT663720	hsa-miR-1301-3p	HITS-CLIP	23824327
MIRT663719	hsa-miR-5047	HITS-CLIP	23824327
MIRT523535	hsa-miR-4511	PAR-CLIP	23446348
MIRT523534	hsa-miR-4716-3p	PAR-CLIP	23446348
MIRT523533	hsa-miR-6794-5p	PAR-CLIP	23446348
MIRT523532	hsa-miR-3192-5p	PAR-CLIP	23446348
MIRT523531	hsa-miR-3185	PAR-CLIP	23446348
MIRT523530	hsa-miR-549a	PAR-CLIP	23446348
MIRT523529	hsa-miR-4481	PAR-CLIP	23446348
MIRT523528	hsa-miR-4745-5p	PAR-CLIP	23446348
MIRT523527	hsa-miR-571	PAR-CLIP	23446348
MIRT523526	hsa-miR-504-3p	PAR-CLIP	23446348
MIRT523525	hsa-miR-122-5p	PAR-CLIP	23446348
MIRT523524	hsa-miR-6878-5p	PAR-CLIP	23446348
MIRT523523	hsa-miR-6731-5p	PAR-CLIP	23446348
MIRT523522	hsa-miR-8085	PAR-CLIP	23446348
MIRT523521	hsa-miR-5187-5p	PAR-CLIP	23446348
MIRT523520	hsa-miR-4271	PAR-CLIP	23446348
MIRT523519	hsa-miR-4725-3p	PAR-CLIP	23446348
MIRT523518	hsa-miR-6780b-5p	PAR-CLIP	23446348
MIRT523517	hsa-miR-625-5p	PAR-CLIP	23446348
MIRT523516	hsa-miR-4654	PAR-CLIP	23446348
MIRT523515	hsa-miR-4769-5p	PAR-CLIP	23446348
MIRT523514	hsa-miR-3198	PAR-CLIP	23446348
MIRT523513	hsa-miR-4309	PAR-CLIP	23446348
MIRT523512	hsa-miR-30c-1-3p	PAR-CLIP	23446348
MIRT523511	hsa-miR-30c-2-3p	PAR-CLIP	23446348
MIRT523510	hsa-miR-6788-5p	PAR-CLIP	23446348
MIRT523509	hsa-miR-6728-5p	PAR-CLIP	23446348
MIRT1022008	hsa-miR-223	CLIP-seq
MIRT1022009	hsa-miR-2276	CLIP-seq
MIRT1022010	hsa-miR-3194-3p	CLIP-seq
MIRT1022011	hsa-miR-323b-3p	CLIP-seq
MIRT1022012	hsa-miR-3616-3p	CLIP-seq
MIRT1022013	hsa-miR-4520a-3p	CLIP-seq
MIRT1022014	hsa-miR-4520b-3p	CLIP-seq
MIRT1022015	hsa-miR-4640-3p	CLIP-seq
MIRT1022016	hsa-miR-4694-3p	CLIP-seq
MIRT1022017	hsa-miR-4697-3p	CLIP-seq
MIRT1022018	hsa-miR-4772-3p	CLIP-seq
MIRT1022019	hsa-miR-522	CLIP-seq
MIRT1022020	hsa-miR-552	CLIP-seq
MIRT1022021	hsa-miR-764	CLIP-seq
MIRT1022022	hsa-miR-802	CLIP-seq
MIRT1022023	hsa-miR-1183	CLIP-seq
MIRT1022024	hsa-miR-1303	CLIP-seq
MIRT1022025	hsa-miR-214	CLIP-seq
MIRT1022026	hsa-miR-25	CLIP-seq
MIRT1022027	hsa-miR-3145-5p	CLIP-seq
MIRT1022028	hsa-miR-3150b-3p	CLIP-seq
MIRT1022029	hsa-miR-32	CLIP-seq
MIRT1022030	hsa-miR-3619-5p	CLIP-seq
MIRT1022031	hsa-miR-363	CLIP-seq
MIRT1022032	hsa-miR-367	CLIP-seq
MIRT1022033	hsa-miR-4274	CLIP-seq
MIRT1022034	hsa-miR-4291	CLIP-seq
MIRT1022035	hsa-miR-4325	CLIP-seq
MIRT1022036	hsa-miR-4496	CLIP-seq
MIRT1022037	hsa-miR-4689	CLIP-seq
MIRT1022038	hsa-miR-4700-3p	CLIP-seq
MIRT1022039	hsa-miR-4784	CLIP-seq
MIRT1022040	hsa-miR-4802-3p	CLIP-seq
MIRT1022041	hsa-miR-761	CLIP-seq
MIRT1022042	hsa-miR-922	CLIP-seq
MIRT1022043	hsa-miR-92a	CLIP-seq
MIRT1022044	hsa-miR-92b	CLIP-seq
MIRT1022045	hsa-miR-1182	CLIP-seq
MIRT1022046	hsa-miR-1207-5p	CLIP-seq
MIRT1022047	hsa-miR-1224-3p	CLIP-seq
MIRT1022048	hsa-miR-1283	CLIP-seq
MIRT1022049	hsa-miR-140-5p	CLIP-seq
MIRT1022050	hsa-miR-1825	CLIP-seq
MIRT1022051	hsa-miR-186	CLIP-seq
MIRT1022052	hsa-miR-188-3p	CLIP-seq
MIRT1022053	hsa-miR-193a-5p	CLIP-seq
MIRT1022054	hsa-miR-199a-5p	CLIP-seq
MIRT1022055	hsa-miR-199b-5p	CLIP-seq
MIRT1022056	hsa-miR-2114	CLIP-seq
MIRT1022057	hsa-miR-2278	CLIP-seq
MIRT1022058	hsa-miR-3123	CLIP-seq
MIRT1022012	hsa-miR-3616-3p	CLIP-seq
MIRT1022059	hsa-miR-3676	CLIP-seq
MIRT1022060	hsa-miR-371b-3p	CLIP-seq
MIRT1022061	hsa-miR-3919	CLIP-seq
MIRT1022062	hsa-miR-3925-3p	CLIP-seq
MIRT1022063	hsa-miR-4286	CLIP-seq
MIRT1022064	hsa-miR-4436b-3p	CLIP-seq
MIRT1022065	hsa-miR-4468	CLIP-seq
MIRT1022066	hsa-miR-4512	CLIP-seq
MIRT1022067	hsa-miR-4540	CLIP-seq
MIRT1022068	hsa-miR-4659a-3p	CLIP-seq
MIRT1022069	hsa-miR-4659b-3p	CLIP-seq
MIRT1022070	hsa-miR-4667-3p	CLIP-seq
MIRT1022071	hsa-miR-4668-3p	CLIP-seq
MIRT1022072	hsa-miR-4719	CLIP-seq
MIRT1022073	hsa-miR-4721	CLIP-seq
MIRT1022074	hsa-miR-4755-3p	CLIP-seq
MIRT1022075	hsa-miR-4761-3p	CLIP-seq
MIRT1022076	hsa-miR-4761-5p	CLIP-seq
MIRT1022077	hsa-miR-4763-3p	CLIP-seq
MIRT1022078	hsa-miR-4778-3p	CLIP-seq
MIRT1022079	hsa-miR-488	CLIP-seq
MIRT1022080	hsa-miR-498	CLIP-seq
MIRT1022081	hsa-miR-515-5p	CLIP-seq
MIRT1022082	hsa-miR-520a-5p	CLIP-seq
MIRT1022083	hsa-miR-525-5p	CLIP-seq
MIRT1022084	hsa-miR-526b	CLIP-seq
MIRT1022085	hsa-miR-541	CLIP-seq
MIRT1022086	hsa-miR-554	CLIP-seq
MIRT1022087	hsa-miR-654-3p	CLIP-seq
MIRT1022088	hsa-miR-654-5p	CLIP-seq
MIRT1022089	hsa-miR-766	CLIP-seq
MIRT1556458	hsa-miR-548b-3p	CLIP-seq
MIRT2002846	hsa-miR-1207-3p	CLIP-seq
MIRT1022063	hsa-miR-4286	CLIP-seq
MIRT2002847	hsa-miR-4301	CLIP-seq
MIRT2002848	hsa-miR-451b	CLIP-seq
MIRT1022074	hsa-miR-4755-3p	CLIP-seq
MIRT1022075	hsa-miR-4761-3p	CLIP-seq
MIRT1022022	hsa-miR-802	CLIP-seq
MIRT1022059	hsa-miR-3676	CLIP-seq
MIRT2002849	hsa-miR-3915	CLIP-seq
MIRT2002850	hsa-miR-3928	CLIP-seq
MIRT2002851	hsa-miR-4328	CLIP-seq
MIRT1022076	hsa-miR-4761-5p	CLIP-seq
MIRT1022080	hsa-miR-498	CLIP-seq
MIRT1556458	hsa-miR-548b-3p	CLIP-seq
MIRT2002846	hsa-miR-1207-3p	CLIP-seq
MIRT1022052	hsa-miR-188-3p	CLIP-seq
MIRT1022056	hsa-miR-2114	CLIP-seq
MIRT2002848	hsa-miR-451b	CLIP-seq
MIRT2450420	hsa-miR-4786-5p	CLIP-seq
MIRT1022086	hsa-miR-554	CLIP-seq
MIRT2539725	hsa-let-7a	CLIP-seq
MIRT2539726	hsa-let-7b	CLIP-seq
MIRT2539727	hsa-let-7c	CLIP-seq
MIRT2539728	hsa-let-7d	CLIP-seq
MIRT2539729	hsa-let-7e	CLIP-seq
MIRT2539730	hsa-let-7f	CLIP-seq
MIRT2539731	hsa-let-7g	CLIP-seq
MIRT2539732	hsa-let-7i	CLIP-seq
MIRT2539733	hsa-miR-1	CLIP-seq
MIRT1022045	hsa-miR-1182	CLIP-seq
MIRT1022046	hsa-miR-1207-5p	CLIP-seq
MIRT1022047	hsa-miR-1224-3p	CLIP-seq
MIRT2539734	hsa-miR-1231	CLIP-seq
MIRT2539735	hsa-miR-1252	CLIP-seq
MIRT2539736	hsa-miR-127-5p	CLIP-seq
MIRT1022048	hsa-miR-1283	CLIP-seq
MIRT2539737	hsa-miR-1285	CLIP-seq
MIRT2539738	hsa-miR-143	CLIP-seq
MIRT2539739	hsa-miR-146b-3p	CLIP-seq
MIRT1022050	hsa-miR-1825	CLIP-seq
MIRT1022053	hsa-miR-193a-5p	CLIP-seq
MIRT1022054	hsa-miR-199a-5p	CLIP-seq
MIRT1022055	hsa-miR-199b-5p	CLIP-seq
MIRT2539740	hsa-miR-203	CLIP-seq
MIRT2539741	hsa-miR-204	CLIP-seq
MIRT2539742	hsa-miR-2052	CLIP-seq
MIRT2539743	hsa-miR-206	CLIP-seq
MIRT2539744	hsa-miR-211	CLIP-seq
MIRT1022025	hsa-miR-214	CLIP-seq
MIRT1022008	hsa-miR-223	CLIP-seq
MIRT1022057	hsa-miR-2278	CLIP-seq
MIRT2539745	hsa-miR-2467-3p	CLIP-seq
MIRT2539746	hsa-miR-3064-3p	CLIP-seq
MIRT2539747	hsa-miR-3127-3p	CLIP-seq
MIRT2539748	hsa-miR-3129-3p	CLIP-seq
MIRT2539749	hsa-miR-3140-3p	CLIP-seq
MIRT2539750	hsa-miR-3145-3p	CLIP-seq
MIRT2539751	hsa-miR-3163	CLIP-seq
MIRT2539752	hsa-miR-3170	CLIP-seq
MIRT2539753	hsa-miR-3187-5p	CLIP-seq
MIRT1022011	hsa-miR-323b-3p	CLIP-seq
MIRT2539754	hsa-miR-335	CLIP-seq
MIRT2539755	hsa-miR-339-5p	CLIP-seq
MIRT2539756	hsa-miR-340	CLIP-seq
MIRT2539757	hsa-miR-3529	CLIP-seq
MIRT2539758	hsa-miR-3607-3p	CLIP-seq
MIRT1022012	hsa-miR-3616-3p	CLIP-seq
MIRT2539759	hsa-miR-3617	CLIP-seq
MIRT1022030	hsa-miR-3619-5p	CLIP-seq
MIRT2539760	hsa-miR-3646	CLIP-seq
MIRT2539761	hsa-miR-3662	CLIP-seq
MIRT2539762	hsa-miR-3673	CLIP-seq
MIRT2539763	hsa-miR-3685	CLIP-seq
MIRT2539764	hsa-miR-3686	CLIP-seq
MIRT1022060	hsa-miR-371b-3p	CLIP-seq
MIRT2539765	hsa-miR-371b-5p	CLIP-seq
MIRT2539766	hsa-miR-379	CLIP-seq
MIRT2539767	hsa-miR-3913-3p	CLIP-seq
MIRT1022062	hsa-miR-3925-3p	CLIP-seq
MIRT2539768	hsa-miR-4257	CLIP-seq
MIRT1022033	hsa-miR-4274	CLIP-seq
MIRT2539769	hsa-miR-4279	CLIP-seq
MIRT2539770	hsa-miR-4282	CLIP-seq
MIRT2539771	hsa-miR-4288	CLIP-seq
MIRT1022034	hsa-miR-4291	CLIP-seq
MIRT2539772	hsa-miR-4424	CLIP-seq
MIRT1022064	hsa-miR-4436b-3p	CLIP-seq
MIRT2539773	hsa-miR-4451	CLIP-seq
MIRT2539774	hsa-miR-4458	CLIP-seq
MIRT1022065	hsa-miR-4468	CLIP-seq
MIRT2539775	hsa-miR-4500	CLIP-seq
MIRT1022066	hsa-miR-4512	CLIP-seq
MIRT2002848	hsa-miR-451b	CLIP-seq
MIRT1022015	hsa-miR-4640-3p	CLIP-seq
MIRT2539776	hsa-miR-4650-3p	CLIP-seq
MIRT1022071	hsa-miR-4668-3p	CLIP-seq
MIRT2539777	hsa-miR-4684-5p	CLIP-seq
MIRT2539778	hsa-miR-4691-5p	CLIP-seq
MIRT1022017	hsa-miR-4697-3p	CLIP-seq
MIRT2539779	hsa-miR-4698	CLIP-seq
MIRT2539780	hsa-miR-4717-3p	CLIP-seq
MIRT1022073	hsa-miR-4721	CLIP-seq
MIRT2539781	hsa-miR-4731-3p	CLIP-seq
MIRT2539782	hsa-miR-4733-5p	CLIP-seq
MIRT1022077	hsa-miR-4763-3p	CLIP-seq
MIRT2539783	hsa-miR-4775	CLIP-seq
MIRT2539784	hsa-miR-4778-5p	CLIP-seq
MIRT2539785	hsa-miR-4780	CLIP-seq
MIRT2539786	hsa-miR-4795-3p	CLIP-seq
MIRT2539787	hsa-miR-4801	CLIP-seq
MIRT1022040	hsa-miR-4802-3p	CLIP-seq
MIRT2539788	hsa-miR-495	CLIP-seq
MIRT2539789	hsa-miR-508-5p	CLIP-seq
MIRT1022081	hsa-miR-515-5p	CLIP-seq
MIRT1022082	hsa-miR-520a-5p	CLIP-seq
MIRT1022019	hsa-miR-522	CLIP-seq
MIRT1022083	hsa-miR-525-5p	CLIP-seq
MIRT1022084	hsa-miR-526b	CLIP-seq
MIRT1022085	hsa-miR-541	CLIP-seq
MIRT2539790	hsa-miR-548ad	CLIP-seq
MIRT1556458	hsa-miR-548b-3p	CLIP-seq
MIRT2539791	hsa-miR-548c-3p	CLIP-seq
MIRT2539792	hsa-miR-548m	CLIP-seq
MIRT2539793	hsa-miR-582-3p	CLIP-seq
MIRT2539794	hsa-miR-590-3p	CLIP-seq
MIRT2539795	hsa-miR-612	CLIP-seq
MIRT2539796	hsa-miR-613	CLIP-seq
MIRT2539797	hsa-miR-623	CLIP-seq
MIRT2539798	hsa-miR-628-3p	CLIP-seq
MIRT2539799	hsa-miR-629	CLIP-seq
MIRT2539800	hsa-miR-632	CLIP-seq
MIRT2539801	hsa-miR-641	CLIP-seq
MIRT1022088	hsa-miR-654-5p	CLIP-seq
MIRT1022041	hsa-miR-761	CLIP-seq
MIRT1022089	hsa-miR-766	CLIP-seq
MIRT1022022	hsa-miR-802	CLIP-seq
MIRT2539802	hsa-miR-888	CLIP-seq
MIRT2539803	hsa-miR-889	CLIP-seq
MIRT1022042	hsa-miR-922	CLIP-seq
MIRT2539804	hsa-miR-98	CLIP-seq
MIRT2539725	hsa-let-7a	CLIP-seq
MIRT2539726	hsa-let-7b	CLIP-seq
MIRT2539727	hsa-let-7c	CLIP-seq
MIRT2539728	hsa-let-7d	CLIP-seq
MIRT2539729	hsa-let-7e	CLIP-seq
MIRT2539730	hsa-let-7f	CLIP-seq
MIRT2539731	hsa-let-7g	CLIP-seq
MIRT2539732	hsa-let-7i	CLIP-seq
MIRT2539733	hsa-miR-1	CLIP-seq
MIRT1022045	hsa-miR-1182	CLIP-seq
MIRT1022046	hsa-miR-1207-5p	CLIP-seq
MIRT1022047	hsa-miR-1224-3p	CLIP-seq
MIRT2539734	hsa-miR-1231	CLIP-seq
MIRT2539735	hsa-miR-1252	CLIP-seq
MIRT2539736	hsa-miR-127-5p	CLIP-seq
MIRT1022048	hsa-miR-1283	CLIP-seq
MIRT2539737	hsa-miR-1285	CLIP-seq
MIRT1022049	hsa-miR-140-5p	CLIP-seq
MIRT2539738	hsa-miR-143	CLIP-seq
MIRT2539739	hsa-miR-146b-3p	CLIP-seq
MIRT1022050	hsa-miR-1825	CLIP-seq
MIRT1022053	hsa-miR-193a-5p	CLIP-seq
MIRT1022054	hsa-miR-199a-5p	CLIP-seq
MIRT1022055	hsa-miR-199b-5p	CLIP-seq
MIRT2539740	hsa-miR-203	CLIP-seq
MIRT2539741	hsa-miR-204	CLIP-seq
MIRT2539742	hsa-miR-2052	CLIP-seq
MIRT2539743	hsa-miR-206	CLIP-seq
MIRT2539744	hsa-miR-211	CLIP-seq
MIRT1022025	hsa-miR-214	CLIP-seq
MIRT1022057	hsa-miR-2278	CLIP-seq
MIRT2539745	hsa-miR-2467-3p	CLIP-seq
MIRT2539746	hsa-miR-3064-3p	CLIP-seq
MIRT2539748	hsa-miR-3129-3p	CLIP-seq
MIRT2539749	hsa-miR-3140-3p	CLIP-seq
MIRT2539750	hsa-miR-3145-3p	CLIP-seq
MIRT2539751	hsa-miR-3163	CLIP-seq
MIRT2539752	hsa-miR-3170	CLIP-seq
MIRT2539753	hsa-miR-3187-5p	CLIP-seq
MIRT2539754	hsa-miR-335	CLIP-seq
MIRT2539755	hsa-miR-339-5p	CLIP-seq
MIRT2539756	hsa-miR-340	CLIP-seq
MIRT2539757	hsa-miR-3529	CLIP-seq
MIRT2539758	hsa-miR-3607-3p	CLIP-seq
MIRT1022012	hsa-miR-3616-3p	CLIP-seq
MIRT2539759	hsa-miR-3617	CLIP-seq
MIRT1022030	hsa-miR-3619-5p	CLIP-seq
MIRT2539760	hsa-miR-3646	CLIP-seq
MIRT2539761	hsa-miR-3662	CLIP-seq
MIRT2539762	hsa-miR-3673	CLIP-seq
MIRT2539764	hsa-miR-3686	CLIP-seq
MIRT1022060	hsa-miR-371b-3p	CLIP-seq
MIRT2539765	hsa-miR-371b-5p	CLIP-seq
MIRT2539766	hsa-miR-379	CLIP-seq
MIRT2539767	hsa-miR-3913-3p	CLIP-seq
MIRT1022062	hsa-miR-3925-3p	CLIP-seq
MIRT2539768	hsa-miR-4257	CLIP-seq
MIRT1022033	hsa-miR-4274	CLIP-seq
MIRT2539769	hsa-miR-4279	CLIP-seq
MIRT2539770	hsa-miR-4282	CLIP-seq
MIRT2539771	hsa-miR-4288	CLIP-seq
MIRT1022034	hsa-miR-4291	CLIP-seq
MIRT1022064	hsa-miR-4436b-3p	CLIP-seq
MIRT2539773	hsa-miR-4451	CLIP-seq
MIRT2539774	hsa-miR-4458	CLIP-seq
MIRT1022065	hsa-miR-4468	CLIP-seq
MIRT2539775	hsa-miR-4500	CLIP-seq
MIRT1022066	hsa-miR-4512	CLIP-seq
MIRT2681668	hsa-miR-4519	CLIP-seq
MIRT2002848	hsa-miR-451b	CLIP-seq
MIRT2539776	hsa-miR-4650-3p	CLIP-seq
MIRT1022071	hsa-miR-4668-3p	CLIP-seq
MIRT2539777	hsa-miR-4684-5p	CLIP-seq
MIRT2539778	hsa-miR-4691-5p	CLIP-seq
MIRT1022016	hsa-miR-4694-3p	CLIP-seq
MIRT2539779	hsa-miR-4698	CLIP-seq
MIRT2539780	hsa-miR-4717-3p	CLIP-seq
MIRT1022073	hsa-miR-4721	CLIP-seq
MIRT2539781	hsa-miR-4731-3p	CLIP-seq
MIRT2539782	hsa-miR-4733-5p	CLIP-seq
MIRT1022077	hsa-miR-4763-3p	CLIP-seq
MIRT2539783	hsa-miR-4775	CLIP-seq
MIRT2539784	hsa-miR-4778-5p	CLIP-seq
MIRT2539785	hsa-miR-4780	CLIP-seq
MIRT2539786	hsa-miR-4795-3p	CLIP-seq
MIRT2539787	hsa-miR-4801	CLIP-seq
MIRT1022040	hsa-miR-4802-3p	CLIP-seq
MIRT2539788	hsa-miR-495	CLIP-seq
MIRT2539789	hsa-miR-508-5p	CLIP-seq
MIRT1022081	hsa-miR-515-5p	CLIP-seq
MIRT1022082	hsa-miR-520a-5p	CLIP-seq
MIRT1022019	hsa-miR-522	CLIP-seq
MIRT1022083	hsa-miR-525-5p	CLIP-seq
MIRT1022084	hsa-miR-526b	CLIP-seq
MIRT1022085	hsa-miR-541	CLIP-seq
MIRT2539790	hsa-miR-548ad	CLIP-seq
MIRT1556458	hsa-miR-548b-3p	CLIP-seq
MIRT2539791	hsa-miR-548c-3p	CLIP-seq
MIRT2539792	hsa-miR-548m	CLIP-seq
MIRT1022020	hsa-miR-552	CLIP-seq
MIRT2539793	hsa-miR-582-3p	CLIP-seq
MIRT2539794	hsa-miR-590-3p	CLIP-seq
MIRT2539795	hsa-miR-612	CLIP-seq
MIRT2539796	hsa-miR-613	CLIP-seq
MIRT2539797	hsa-miR-623	CLIP-seq
MIRT2539798	hsa-miR-628-3p	CLIP-seq
MIRT2539799	hsa-miR-629	CLIP-seq
MIRT2539800	hsa-miR-632	CLIP-seq
MIRT2539801	hsa-miR-641	CLIP-seq
MIRT1022088	hsa-miR-654-5p	CLIP-seq
MIRT2681669	hsa-miR-671-5p	CLIP-seq
MIRT1022041	hsa-miR-761	CLIP-seq
MIRT1022021	hsa-miR-764	CLIP-seq
MIRT1022089	hsa-miR-766	CLIP-seq
MIRT1022022	hsa-miR-802	CLIP-seq
MIRT2539802	hsa-miR-888	CLIP-seq
MIRT1022042	hsa-miR-922	CLIP-seq
MIRT2539804	hsa-miR-98	CLIP-seq

Show/Hide all(28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001504	Process	Neurotransmitter uptake	TAS
GO:0001525	Process	Angiogenesis	IEA
GO:0004356	Function	Glutamate-ammonia ligase activity	IBA	21873635
GO:0004356	Function	Glutamate-ammonia ligase activity	IDA	30158707
GO:0005515	Function	Protein binding	IPI	21994455, 25910212, 30158707
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005739	Component	Mitochondrion	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005829	Component	Cytosol	IDA	30158707
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	30158707
GO:0006538	Process	Glutamate catabolic process	TAS	21757002
GO:0006542	Process	Glutamine biosynthetic process	IBA	21873635
GO:0006542	Process	Glutamine biosynthetic process	TAS	21757002
GO:0008283	Process	Cell population proliferation	IDA	18662667
GO:0008652	Process	Cellular amino acid biosynthetic process	TAS
GO:0010594	Process	Regulation of endothelial cell migration	IDA	30158707
GO:0018215	Process	Protein phosphopantetheinylation	IEA
GO:0018345	Process	Protein palmitoylation	IDA	30158707
GO:0019706	Function	Protein-cysteine S-palmitoyltransferase activity	IDA	30158707
GO:0042254	Process	Ribosome biogenesis	IMP	26711351
GO:0042802	Function	Identical protein binding	IPI	16189514, 19447967, 21988832, 25416956, 25502805, 31515488
GO:0046872	Function	Metal ion binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:1903670	Process	Regulation of sprouting angiogenesis	IDA	30158707
GO:1904749	Process	Regulation of protein localization to nucleolus	IMP	26711351

MIM	HGNC	e!Ensembl
138290	4341	ENSG00000135821

Protein

UniProt ID

P15104

Protein name

Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Palmitoyltransferase GLUL) (EC 2.3.1.225)

Protein function

Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (PubMed:16267323, PubMed:30158707, PubMed:36289327). Its role depends on tissue localization: in the brain, it regulates the levels of toxic a

PDB

2OJW , 2QC8 , 7EVT , 8DNU

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03951	Gln-synt_N	24 → 104	Glutamine synthetase, beta-Grasp domain	Domain
PF00120	Gln-synt_C	110 → 361	Glutamine synthetase, catalytic domain	Domain

Sequence

MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW
NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI
MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY
RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP
KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL
TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL
LNETGDEPFQYKN

Sequence length

373

Interactions

View interactions

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