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GFPT2 (glutamine-fructose-6-phosphate transaminase 2)

Gene

9945

Glutamine-fructose-6-phosphate transaminase 2

GFPT2

GFAT, GFAT 2, GFAT2

5q35.3

Show/Hide all(196)

miRTarBase ID	miRNA	Experiments	Reference
MIRT021918	hsa-miR-128-3p	Sequencing	20371350
MIRT022362	hsa-miR-124-3p	Microarray	18668037
MIRT023459	hsa-miR-30b-5p	Sequencing	20371350
MIRT027274	hsa-miR-101-3p	Sequencing	20371350
MIRT028277	hsa-miR-32-5p	Sequencing	20371350
MIRT045625	hsa-miR-149-5p	CLASH	23622248
MIRT537188	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT537187	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT537186	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT537185	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT028277	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT537184	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT537183	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT537182	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT537181	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT537180	hsa-miR-3681-5p	PAR-CLIP	21572407
MIRT537179	hsa-miR-6849-5p	PAR-CLIP	21572407
MIRT537178	hsa-miR-3675-3p	PAR-CLIP	21572407
MIRT537177	hsa-miR-767-3p	PAR-CLIP	21572407
MIRT537176	hsa-miR-4434	PAR-CLIP	21572407
MIRT537175	hsa-miR-4516	PAR-CLIP	21572407
MIRT537173	hsa-miR-5703	PAR-CLIP	21572407
MIRT537174	hsa-miR-6828-3p	PAR-CLIP	21572407
MIRT537172	hsa-miR-4531	PAR-CLIP	21572407
MIRT537188	hsa-miR-199a-3p	PAR-CLIP	22012620
MIRT537187	hsa-miR-3129-5p	PAR-CLIP	22012620
MIRT537186	hsa-miR-199b-3p	PAR-CLIP	22012620
MIRT537185	hsa-miR-363-3p	PAR-CLIP	22012620
MIRT028277	hsa-miR-32-5p	PAR-CLIP	22012620
MIRT537184	hsa-miR-25-3p	PAR-CLIP	22012620
MIRT537183	hsa-miR-367-3p	PAR-CLIP	22012620
MIRT537182	hsa-miR-92b-3p	PAR-CLIP	22012620
MIRT537181	hsa-miR-92a-3p	PAR-CLIP	22012620
MIRT537180	hsa-miR-3681-5p	PAR-CLIP	22012620
MIRT537179	hsa-miR-6849-5p	PAR-CLIP	22012620
MIRT537178	hsa-miR-3675-3p	PAR-CLIP	22012620
MIRT537177	hsa-miR-767-3p	PAR-CLIP	22012620
MIRT537176	hsa-miR-4434	PAR-CLIP	22012620
MIRT537175	hsa-miR-4516	PAR-CLIP	22012620
MIRT537173	hsa-miR-5703	PAR-CLIP	22012620
MIRT537174	hsa-miR-6828-3p	PAR-CLIP	22012620
MIRT537172	hsa-miR-4531	PAR-CLIP	22012620
MIRT734744	hsa-miR-27a-3p	Luciferase reporter assay, Western blotting, Microarray, Immunohistochemistry (IHC), Immunofluorescence, ChIP-seq, qRT-PCR	33910455
MIRT734744	hsa-miR-27a-3p	Luciferase reporter assay, Western blotting, Microarray, Immunoprecipitaion (IP), Immunofluorescence, qRT-PCR, Flow cytometry	33910455
MIRT537188	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT537187	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT537186	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT537185	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT028277	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT537184	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT537183	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT537182	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT537181	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT537180	hsa-miR-3681-5p	PAR-CLIP	21572407
MIRT537179	hsa-miR-6849-5p	PAR-CLIP	21572407
MIRT537178	hsa-miR-3675-3p	PAR-CLIP	21572407
MIRT537177	hsa-miR-767-3p	PAR-CLIP	21572407
MIRT537176	hsa-miR-4434	PAR-CLIP	21572407
MIRT537175	hsa-miR-4516	PAR-CLIP	21572407
MIRT537173	hsa-miR-5703	PAR-CLIP	21572407
MIRT537174	hsa-miR-6828-3p	PAR-CLIP	21572407
MIRT537172	hsa-miR-4531	PAR-CLIP	21572407
MIRT537188	hsa-miR-199a-3p	PAR-CLIP	22012620
MIRT537187	hsa-miR-3129-5p	PAR-CLIP	22012620
MIRT537186	hsa-miR-199b-3p	PAR-CLIP	22012620
MIRT537185	hsa-miR-363-3p	PAR-CLIP	22012620
MIRT028277	hsa-miR-32-5p	PAR-CLIP	22012620
MIRT537184	hsa-miR-25-3p	PAR-CLIP	22012620
MIRT537183	hsa-miR-367-3p	PAR-CLIP	22012620
MIRT537182	hsa-miR-92b-3p	PAR-CLIP	22012620
MIRT537181	hsa-miR-92a-3p	PAR-CLIP	22012620
MIRT537180	hsa-miR-3681-5p	PAR-CLIP	22012620
MIRT537179	hsa-miR-6849-5p	PAR-CLIP	22012620
MIRT537178	hsa-miR-3675-3p	PAR-CLIP	22012620
MIRT537177	hsa-miR-767-3p	PAR-CLIP	22012620
MIRT537176	hsa-miR-4434	PAR-CLIP	22012620
MIRT537175	hsa-miR-4516	PAR-CLIP	22012620
MIRT537173	hsa-miR-5703	PAR-CLIP	22012620
MIRT537174	hsa-miR-6828-3p	PAR-CLIP	22012620
MIRT537172	hsa-miR-4531	PAR-CLIP	22012620
MIRT1017166	hsa-miR-139-5p	CLIP-seq
MIRT1017167	hsa-miR-4700-3p	CLIP-seq
MIRT2234433	hsa-miR-3194-3p	CLIP-seq
MIRT2234434	hsa-miR-3681	CLIP-seq
MIRT2234435	hsa-miR-4459	CLIP-seq
MIRT2234436	hsa-miR-4709-3p	CLIP-seq
MIRT2538527	hsa-miR-1254	CLIP-seq
MIRT2538528	hsa-miR-1265	CLIP-seq
MIRT2538529	hsa-miR-1276	CLIP-seq
MIRT2538530	hsa-miR-128	CLIP-seq
MIRT2538531	hsa-miR-1284	CLIP-seq
MIRT2538532	hsa-miR-2392	CLIP-seq
MIRT2538533	hsa-miR-25	CLIP-seq
MIRT2538534	hsa-miR-27a	CLIP-seq
MIRT2538535	hsa-miR-27b	CLIP-seq
MIRT2538536	hsa-miR-28-3p	CLIP-seq
MIRT2538537	hsa-miR-30a	CLIP-seq
MIRT2538538	hsa-miR-30b	CLIP-seq
MIRT2538539	hsa-miR-30c	CLIP-seq
MIRT2538540	hsa-miR-30d	CLIP-seq
MIRT2538541	hsa-miR-30e	CLIP-seq
MIRT2538542	hsa-miR-3116	CLIP-seq
MIRT2538543	hsa-miR-3132	CLIP-seq
MIRT2538544	hsa-miR-3145-3p	CLIP-seq
MIRT2538545	hsa-miR-3158-3p	CLIP-seq
MIRT2538546	hsa-miR-3163	CLIP-seq
MIRT2234433	hsa-miR-3194-3p	CLIP-seq
MIRT2538547	hsa-miR-32	CLIP-seq
MIRT2538548	hsa-miR-340	CLIP-seq
MIRT2538549	hsa-miR-363	CLIP-seq
MIRT2538550	hsa-miR-3655	CLIP-seq
MIRT2538551	hsa-miR-3664-5p	CLIP-seq
MIRT2538552	hsa-miR-367	CLIP-seq
MIRT2234434	hsa-miR-3681	CLIP-seq
MIRT2538553	hsa-miR-3690	CLIP-seq
MIRT2538554	hsa-miR-383	CLIP-seq
MIRT2538555	hsa-miR-4255	CLIP-seq
MIRT2538556	hsa-miR-4528	CLIP-seq
MIRT2538557	hsa-miR-4638-3p	CLIP-seq
MIRT2538558	hsa-miR-4685-5p	CLIP-seq
MIRT2538559	hsa-miR-4698	CLIP-seq
MIRT2234436	hsa-miR-4709-3p	CLIP-seq
MIRT2538560	hsa-miR-4714-5p	CLIP-seq
MIRT2538561	hsa-miR-4715-3p	CLIP-seq
MIRT2538562	hsa-miR-4722-3p	CLIP-seq
MIRT2538563	hsa-miR-4738-3p	CLIP-seq
MIRT2538564	hsa-miR-4755-3p	CLIP-seq
MIRT2538565	hsa-miR-4772-5p	CLIP-seq
MIRT2538566	hsa-miR-498	CLIP-seq
MIRT2538567	hsa-miR-513a-5p	CLIP-seq
MIRT2538568	hsa-miR-548v	CLIP-seq
MIRT2538569	hsa-miR-606	CLIP-seq
MIRT2538570	hsa-miR-618	CLIP-seq
MIRT2538571	hsa-miR-665	CLIP-seq
MIRT2538572	hsa-miR-92a	CLIP-seq
MIRT2538573	hsa-miR-92b	CLIP-seq
MIRT2538574	hsa-miR-935	CLIP-seq
MIRT2538527	hsa-miR-1254	CLIP-seq
MIRT2538528	hsa-miR-1265	CLIP-seq
MIRT2681518	hsa-miR-1270	CLIP-seq
MIRT2681519	hsa-miR-1273	CLIP-seq
MIRT2538529	hsa-miR-1276	CLIP-seq
MIRT2538530	hsa-miR-128	CLIP-seq
MIRT2538531	hsa-miR-1284	CLIP-seq
MIRT2681520	hsa-miR-204	CLIP-seq
MIRT2681521	hsa-miR-211	CLIP-seq
MIRT2538532	hsa-miR-2392	CLIP-seq
MIRT2538533	hsa-miR-25	CLIP-seq
MIRT2538534	hsa-miR-27a	CLIP-seq
MIRT2538535	hsa-miR-27b	CLIP-seq
MIRT2538536	hsa-miR-28-3p	CLIP-seq
MIRT2538537	hsa-miR-30a	CLIP-seq
MIRT2538538	hsa-miR-30b	CLIP-seq
MIRT2538539	hsa-miR-30c	CLIP-seq
MIRT2538540	hsa-miR-30d	CLIP-seq
MIRT2538541	hsa-miR-30e	CLIP-seq
MIRT2538542	hsa-miR-3116	CLIP-seq
MIRT2538543	hsa-miR-3132	CLIP-seq
MIRT2538544	hsa-miR-3145-3p	CLIP-seq
MIRT2538545	hsa-miR-3158-3p	CLIP-seq
MIRT2538546	hsa-miR-3163	CLIP-seq
MIRT2234433	hsa-miR-3194-3p	CLIP-seq
MIRT2538547	hsa-miR-32	CLIP-seq
MIRT2538548	hsa-miR-340	CLIP-seq
MIRT2538549	hsa-miR-363	CLIP-seq
MIRT2538551	hsa-miR-3664-5p	CLIP-seq
MIRT2538552	hsa-miR-367	CLIP-seq
MIRT2234434	hsa-miR-3681	CLIP-seq
MIRT2538553	hsa-miR-3690	CLIP-seq
MIRT2538554	hsa-miR-383	CLIP-seq
MIRT2681522	hsa-miR-3938	CLIP-seq
MIRT2538555	hsa-miR-4255	CLIP-seq
MIRT2681523	hsa-miR-4279	CLIP-seq
MIRT2538556	hsa-miR-4528	CLIP-seq
MIRT2538557	hsa-miR-4638-3p	CLIP-seq
MIRT2538558	hsa-miR-4685-5p	CLIP-seq
MIRT2538559	hsa-miR-4698	CLIP-seq
MIRT2234436	hsa-miR-4709-3p	CLIP-seq
MIRT2538560	hsa-miR-4714-5p	CLIP-seq
MIRT2538561	hsa-miR-4715-3p	CLIP-seq
MIRT2538562	hsa-miR-4722-3p	CLIP-seq
MIRT2538563	hsa-miR-4738-3p	CLIP-seq
MIRT2538564	hsa-miR-4755-3p	CLIP-seq
MIRT2681524	hsa-miR-4755-5p	CLIP-seq
MIRT2538565	hsa-miR-4772-5p	CLIP-seq
MIRT2538566	hsa-miR-498	CLIP-seq
MIRT2538567	hsa-miR-513a-5p	CLIP-seq
MIRT2538568	hsa-miR-548v	CLIP-seq
MIRT2538569	hsa-miR-606	CLIP-seq
MIRT2538570	hsa-miR-618	CLIP-seq
MIRT2681525	hsa-miR-620	CLIP-seq
MIRT2681526	hsa-miR-623	CLIP-seq
MIRT2538571	hsa-miR-665	CLIP-seq
MIRT2538572	hsa-miR-92a	CLIP-seq
MIRT2538573	hsa-miR-92b	CLIP-seq
MIRT2538574	hsa-miR-935	CLIP-seq

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004360	Function	Glutamine-fructose-6-phosphate transaminase (isomerizing) activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	21044950
GO:0005829	Component	Cytosol	TAS
GO:0006002	Process	Fructose 6-phosphate metabolic process	IBA	21873635
GO:0006047	Process	UDP-N-acetylglucosamine metabolic process	IBA	21873635
GO:0006048	Process	UDP-N-acetylglucosamine biosynthetic process	IEA
GO:0006048	Process	UDP-N-acetylglucosamine biosynthetic process	TAS
GO:0006112	Process	Energy reserve metabolic process	TAS	10198162
GO:0006487	Process	Protein N-linked glycosylation	IBA	21873635
GO:0006541	Process	Glutamine metabolic process	IEA
GO:0097367	Function	Carbohydrate derivative binding	IEA
GO:1990830	Process	Cellular response to leukemia inhibitory factor	IEA

MIM	HGNC	e!Ensembl
603865	4242	ENSG00000131459

Protein

UniProt ID

O94808

Protein name

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2)

Protein function

Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13522	GATase_6	68 → 212		Domain
PF01380	SIS	363 → 492	SIS domain	Domain
PF01380	SIS	534 → 665	SIS domain	Domain

Sequence

MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNHEVKERHIQLVKKR
GKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHN
GIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEG
AFALVFKSVHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPILYRTCTLENVKNICKTRMK
RLDSSACLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSAS
DDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDH
LKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFF
ISQSGETADTLLALRYCKDRGALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYT
SQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEVLSLEEKIHDLALELYTQRS
LLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCF
AKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFH
LAVLRGYDVDFPRNLAKSVTVE

Sequence length

682

Interactions

View interactions

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