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CTNNA1 (catenin alpha 1)

Gene

1495

Catenin alpha 1

CTNNA1

CAP102, MDBS2, MDPT2

5q31.2

This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains th

Show/Hide all(5)

SNP ID	Visualize variation	Clinical significance	Consequence
rs755215402	T>A,C,G	Pathogenic, likely-benign	Missense variant, 5 prime UTR variant, coding sequence variant, intron variant, synonymous variant
rs869312766	TGAA>-	Likely-pathogenic	Intron variant, genic upstream transcript variant, coding sequence variant, frameshift variant, 5 prime UTR variant
rs869320696	T>C	Pathogenic	Coding sequence variant, missense variant, genic upstream transcript variant
rs869320697	G>A	Pathogenic	Coding sequence variant, missense variant, genic upstream transcript variant
rs1554085478	C>T	Uncertain-significance, likely-pathogenic	Coding sequence variant, missense variant, genic upstream transcript variant

Show/Hide all(509)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020722	hsa-miR-155-5p	Proteomics	18668040
MIRT039674	hsa-miR-615-3p	CLASH	23622248
MIRT039085	hsa-miR-769-3p	CLASH	23622248
MIRT038473	hsa-miR-296-3p	CLASH	23622248
MIRT037739	hsa-miR-744-5p	CLASH	23622248
MIRT440863	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440863	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT914821	hsa-miR-101	CLIP-seq
MIRT914822	hsa-miR-103a	CLIP-seq
MIRT914823	hsa-miR-107	CLIP-seq
MIRT914824	hsa-miR-1183	CLIP-seq
MIRT914825	hsa-miR-1184	CLIP-seq
MIRT914826	hsa-miR-1225-3p	CLIP-seq
MIRT914827	hsa-miR-1234	CLIP-seq
MIRT914828	hsa-miR-1285	CLIP-seq
MIRT914829	hsa-miR-1288	CLIP-seq
MIRT914830	hsa-miR-1292	CLIP-seq
MIRT914831	hsa-miR-134	CLIP-seq
MIRT914832	hsa-miR-139-5p	CLIP-seq
MIRT914833	hsa-miR-141	CLIP-seq
MIRT914834	hsa-miR-144	CLIP-seq
MIRT914835	hsa-miR-183	CLIP-seq
MIRT914836	hsa-miR-200a	CLIP-seq
MIRT914837	hsa-miR-2115	CLIP-seq
MIRT914838	hsa-miR-299-3p	CLIP-seq
MIRT914839	hsa-miR-3118	CLIP-seq
MIRT914840	hsa-miR-3136-5p	CLIP-seq
MIRT914841	hsa-miR-3137	CLIP-seq
MIRT914842	hsa-miR-3145-3p	CLIP-seq
MIRT914843	hsa-miR-3153	CLIP-seq
MIRT914844	hsa-miR-3180	CLIP-seq
MIRT914845	hsa-miR-3180-3p	CLIP-seq
MIRT914846	hsa-miR-3187-5p	CLIP-seq
MIRT914847	hsa-miR-3192	CLIP-seq
MIRT914848	hsa-miR-3196	CLIP-seq
MIRT914849	hsa-miR-3199	CLIP-seq
MIRT914850	hsa-miR-323-3p	CLIP-seq
MIRT914851	hsa-miR-34b	CLIP-seq
MIRT914852	hsa-miR-34c-3p	CLIP-seq
MIRT914853	hsa-miR-3591-5p	CLIP-seq
MIRT914854	hsa-miR-3681	CLIP-seq
MIRT914855	hsa-miR-376a	CLIP-seq
MIRT914856	hsa-miR-376b	CLIP-seq
MIRT914857	hsa-miR-3925-3p	CLIP-seq
MIRT914858	hsa-miR-4261	CLIP-seq
MIRT914859	hsa-miR-4280	CLIP-seq
MIRT914860	hsa-miR-4297	CLIP-seq
MIRT914861	hsa-miR-4314	CLIP-seq
MIRT914862	hsa-miR-4320	CLIP-seq
MIRT914863	hsa-miR-4418	CLIP-seq
MIRT914864	hsa-miR-4426	CLIP-seq
MIRT914865	hsa-miR-4433	CLIP-seq
MIRT914866	hsa-miR-4439	CLIP-seq
MIRT914867	hsa-miR-4440	CLIP-seq
MIRT914868	hsa-miR-4447	CLIP-seq
MIRT914869	hsa-miR-4459	CLIP-seq
MIRT914870	hsa-miR-4471	CLIP-seq
MIRT914871	hsa-miR-4472	CLIP-seq
MIRT914872	hsa-miR-4477a	CLIP-seq
MIRT914873	hsa-miR-4488	CLIP-seq
MIRT914874	hsa-miR-4513	CLIP-seq
MIRT914875	hsa-miR-4642	CLIP-seq
MIRT914876	hsa-miR-4646-5p	CLIP-seq
MIRT914877	hsa-miR-4647	CLIP-seq
MIRT914878	hsa-miR-4648	CLIP-seq
MIRT914879	hsa-miR-4651	CLIP-seq
MIRT914880	hsa-miR-4654	CLIP-seq
MIRT914881	hsa-miR-4658	CLIP-seq
MIRT914882	hsa-miR-4662b	CLIP-seq
MIRT914883	hsa-miR-4668-5p	CLIP-seq
MIRT914884	hsa-miR-4670-3p	CLIP-seq
MIRT914885	hsa-miR-4685-5p	CLIP-seq
MIRT914886	hsa-miR-4697-5p	CLIP-seq
MIRT914887	hsa-miR-4705	CLIP-seq
MIRT914888	hsa-miR-4719	CLIP-seq
MIRT914889	hsa-miR-4726-3p	CLIP-seq
MIRT914890	hsa-miR-4753-3p	CLIP-seq
MIRT914891	hsa-miR-4758-5p	CLIP-seq
MIRT914892	hsa-miR-4760-3p	CLIP-seq
MIRT914893	hsa-miR-4765	CLIP-seq
MIRT914894	hsa-miR-4766-3p	CLIP-seq
MIRT914895	hsa-miR-4768-3p	CLIP-seq
MIRT914896	hsa-miR-4769-5p	CLIP-seq
MIRT914897	hsa-miR-4781-3p	CLIP-seq
MIRT914898	hsa-miR-4799-5p	CLIP-seq
MIRT914899	hsa-miR-503	CLIP-seq
MIRT914900	hsa-miR-509-3-5p	CLIP-seq
MIRT914901	hsa-miR-509-5p	CLIP-seq
MIRT914902	hsa-miR-515-5p	CLIP-seq
MIRT914903	hsa-miR-516a-3p	CLIP-seq
MIRT914904	hsa-miR-532-5p	CLIP-seq
MIRT914905	hsa-miR-548ag	CLIP-seq
MIRT914906	hsa-miR-548ai	CLIP-seq
MIRT914907	hsa-miR-548p	CLIP-seq
MIRT914908	hsa-miR-579	CLIP-seq
MIRT914909	hsa-miR-586	CLIP-seq
MIRT914910	hsa-miR-608	CLIP-seq
MIRT914911	hsa-miR-612	CLIP-seq
MIRT914912	hsa-miR-659	CLIP-seq
MIRT914913	hsa-miR-661	CLIP-seq
MIRT914914	hsa-miR-664	CLIP-seq
MIRT914915	hsa-miR-766	CLIP-seq
MIRT914916	hsa-miR-769-5p	CLIP-seq
MIRT914917	hsa-miR-891b	CLIP-seq
MIRT914918	hsa-miR-9	CLIP-seq
MIRT914919	hsa-miR-944	CLIP-seq
MIRT1547675	hsa-miR-1269	CLIP-seq
MIRT1547676	hsa-miR-1269b	CLIP-seq
MIRT914829	hsa-miR-1288	CLIP-seq
MIRT1547677	hsa-miR-378	CLIP-seq
MIRT1547678	hsa-miR-378b	CLIP-seq
MIRT1547679	hsa-miR-378c	CLIP-seq
MIRT1547680	hsa-miR-378d	CLIP-seq
MIRT1547681	hsa-miR-378e	CLIP-seq
MIRT1547682	hsa-miR-378f	CLIP-seq
MIRT1547683	hsa-miR-378h	CLIP-seq
MIRT1547684	hsa-miR-378i	CLIP-seq
MIRT1547685	hsa-miR-422a	CLIP-seq
MIRT1547686	hsa-miR-4515	CLIP-seq
MIRT1547687	hsa-miR-4740-5p	CLIP-seq
MIRT914821	hsa-miR-101	CLIP-seq
MIRT914822	hsa-miR-103a	CLIP-seq
MIRT914823	hsa-miR-107	CLIP-seq
MIRT914824	hsa-miR-1183	CLIP-seq
MIRT914825	hsa-miR-1184	CLIP-seq
MIRT914829	hsa-miR-1288	CLIP-seq
MIRT1971390	hsa-miR-133a	CLIP-seq
MIRT1971391	hsa-miR-133b	CLIP-seq
MIRT914832	hsa-miR-139-5p	CLIP-seq
MIRT1971392	hsa-miR-140-3p	CLIP-seq
MIRT914833	hsa-miR-141	CLIP-seq
MIRT914834	hsa-miR-144	CLIP-seq
MIRT914836	hsa-miR-200a	CLIP-seq
MIRT914837	hsa-miR-2115	CLIP-seq
MIRT1971393	hsa-miR-2276	CLIP-seq
MIRT914838	hsa-miR-299-3p	CLIP-seq
MIRT1971394	hsa-miR-3123	CLIP-seq
MIRT1971395	hsa-miR-3130-3p	CLIP-seq
MIRT914842	hsa-miR-3145-3p	CLIP-seq
MIRT1971396	hsa-miR-3190	CLIP-seq
MIRT914849	hsa-miR-3199	CLIP-seq
MIRT914850	hsa-miR-323-3p	CLIP-seq
MIRT1971397	hsa-miR-325	CLIP-seq
MIRT1971398	hsa-miR-339-5p	CLIP-seq
MIRT914851	hsa-miR-34b	CLIP-seq
MIRT1971399	hsa-miR-3613-5p	CLIP-seq
MIRT914855	hsa-miR-376a	CLIP-seq
MIRT914856	hsa-miR-376b	CLIP-seq
MIRT1971400	hsa-miR-3925-5p	CLIP-seq
MIRT1971401	hsa-miR-3976	CLIP-seq
MIRT914858	hsa-miR-4261	CLIP-seq
MIRT1971402	hsa-miR-4282	CLIP-seq
MIRT1971403	hsa-miR-4302	CLIP-seq
MIRT914862	hsa-miR-4320	CLIP-seq
MIRT1971404	hsa-miR-4328	CLIP-seq
MIRT914863	hsa-miR-4418	CLIP-seq
MIRT914864	hsa-miR-4426	CLIP-seq
MIRT1971405	hsa-miR-4446-5p	CLIP-seq
MIRT914872	hsa-miR-4477a	CLIP-seq
MIRT1971406	hsa-miR-4637	CLIP-seq
MIRT914877	hsa-miR-4647	CLIP-seq
MIRT914878	hsa-miR-4648	CLIP-seq
MIRT914880	hsa-miR-4654	CLIP-seq
MIRT914881	hsa-miR-4658	CLIP-seq
MIRT914882	hsa-miR-4662b	CLIP-seq
MIRT914884	hsa-miR-4670-3p	CLIP-seq
MIRT914888	hsa-miR-4719	CLIP-seq
MIRT914889	hsa-miR-4726-3p	CLIP-seq
MIRT1971407	hsa-miR-4729	CLIP-seq
MIRT914890	hsa-miR-4753-3p	CLIP-seq
MIRT1971408	hsa-miR-4755-5p	CLIP-seq
MIRT914891	hsa-miR-4758-5p	CLIP-seq
MIRT914892	hsa-miR-4760-3p	CLIP-seq
MIRT914893	hsa-miR-4765	CLIP-seq
MIRT914894	hsa-miR-4766-3p	CLIP-seq
MIRT914896	hsa-miR-4769-5p	CLIP-seq
MIRT914897	hsa-miR-4781-3p	CLIP-seq
MIRT914898	hsa-miR-4799-5p	CLIP-seq
MIRT914899	hsa-miR-503	CLIP-seq
MIRT914900	hsa-miR-509-3-5p	CLIP-seq
MIRT914901	hsa-miR-509-5p	CLIP-seq
MIRT914903	hsa-miR-516a-3p	CLIP-seq
MIRT1971409	hsa-miR-544	CLIP-seq
MIRT914905	hsa-miR-548ag	CLIP-seq
MIRT914906	hsa-miR-548ai	CLIP-seq
MIRT914907	hsa-miR-548p	CLIP-seq
MIRT914908	hsa-miR-579	CLIP-seq
MIRT914909	hsa-miR-586	CLIP-seq
MIRT1971410	hsa-miR-628-3p	CLIP-seq
MIRT914912	hsa-miR-659	CLIP-seq
MIRT914914	hsa-miR-664	CLIP-seq
MIRT1971411	hsa-miR-670	CLIP-seq
MIRT914918	hsa-miR-9	CLIP-seq
MIRT914919	hsa-miR-944	CLIP-seq
MIRT914821	hsa-miR-101	CLIP-seq
MIRT914822	hsa-miR-103a	CLIP-seq
MIRT914823	hsa-miR-107	CLIP-seq
MIRT914824	hsa-miR-1183	CLIP-seq
MIRT914825	hsa-miR-1184	CLIP-seq
MIRT914826	hsa-miR-1225-3p	CLIP-seq
MIRT2206976	hsa-miR-1231	CLIP-seq
MIRT2206977	hsa-miR-1233	CLIP-seq
MIRT1547675	hsa-miR-1269	CLIP-seq
MIRT1547676	hsa-miR-1269b	CLIP-seq
MIRT2206978	hsa-miR-1272	CLIP-seq
MIRT914829	hsa-miR-1288	CLIP-seq
MIRT914830	hsa-miR-1292	CLIP-seq
MIRT914831	hsa-miR-134	CLIP-seq
MIRT914832	hsa-miR-139-5p	CLIP-seq
MIRT914833	hsa-miR-141	CLIP-seq
MIRT914834	hsa-miR-144	CLIP-seq
MIRT914836	hsa-miR-200a	CLIP-seq
MIRT2206979	hsa-miR-204	CLIP-seq
MIRT2206980	hsa-miR-211	CLIP-seq
MIRT1971393	hsa-miR-2276	CLIP-seq
MIRT2206981	hsa-miR-2355-3p	CLIP-seq
MIRT914838	hsa-miR-299-3p	CLIP-seq
MIRT914839	hsa-miR-3118	CLIP-seq
MIRT2206982	hsa-miR-3120-5p	CLIP-seq
MIRT1971394	hsa-miR-3123	CLIP-seq
MIRT1971395	hsa-miR-3130-3p	CLIP-seq
MIRT914840	hsa-miR-3136-5p	CLIP-seq
MIRT914841	hsa-miR-3137	CLIP-seq
MIRT914842	hsa-miR-3145-3p	CLIP-seq
MIRT2206983	hsa-miR-3174	CLIP-seq
MIRT914847	hsa-miR-3192	CLIP-seq
MIRT914850	hsa-miR-323-3p	CLIP-seq
MIRT1971397	hsa-miR-325	CLIP-seq
MIRT914851	hsa-miR-34b	CLIP-seq
MIRT914852	hsa-miR-34c-3p	CLIP-seq
MIRT1971399	hsa-miR-3613-5p	CLIP-seq
MIRT2206984	hsa-miR-371-5p	CLIP-seq
MIRT2206985	hsa-miR-371b-5p	CLIP-seq
MIRT1547677	hsa-miR-378	CLIP-seq
MIRT1547678	hsa-miR-378b	CLIP-seq
MIRT1547679	hsa-miR-378c	CLIP-seq
MIRT1547680	hsa-miR-378d	CLIP-seq
MIRT1547681	hsa-miR-378e	CLIP-seq
MIRT1547682	hsa-miR-378f	CLIP-seq
MIRT1547683	hsa-miR-378h	CLIP-seq
MIRT1547684	hsa-miR-378i	CLIP-seq
MIRT914857	hsa-miR-3925-3p	CLIP-seq
MIRT1971400	hsa-miR-3925-5p	CLIP-seq
MIRT2206986	hsa-miR-3938	CLIP-seq
MIRT2206987	hsa-miR-3945	CLIP-seq
MIRT1971401	hsa-miR-3976	CLIP-seq
MIRT1547685	hsa-miR-422a	CLIP-seq
MIRT2206988	hsa-miR-4253	CLIP-seq
MIRT914858	hsa-miR-4261	CLIP-seq
MIRT2206989	hsa-miR-4274	CLIP-seq
MIRT914860	hsa-miR-4297	CLIP-seq
MIRT1971403	hsa-miR-4302	CLIP-seq
MIRT2206990	hsa-miR-4307	CLIP-seq
MIRT914861	hsa-miR-4314	CLIP-seq
MIRT914862	hsa-miR-4320	CLIP-seq
MIRT1971404	hsa-miR-4328	CLIP-seq
MIRT2206991	hsa-miR-433	CLIP-seq
MIRT914863	hsa-miR-4418	CLIP-seq
MIRT914866	hsa-miR-4439	CLIP-seq
MIRT914870	hsa-miR-4471	CLIP-seq
MIRT914872	hsa-miR-4477a	CLIP-seq
MIRT914874	hsa-miR-4513	CLIP-seq
MIRT1547686	hsa-miR-4515	CLIP-seq
MIRT1971406	hsa-miR-4637	CLIP-seq
MIRT2206992	hsa-miR-4638-3p	CLIP-seq
MIRT914875	hsa-miR-4642	CLIP-seq
MIRT2206993	hsa-miR-4646-3p	CLIP-seq
MIRT914876	hsa-miR-4646-5p	CLIP-seq
MIRT914878	hsa-miR-4648	CLIP-seq
MIRT914880	hsa-miR-4654	CLIP-seq
MIRT914881	hsa-miR-4658	CLIP-seq
MIRT2206994	hsa-miR-4659a-3p	CLIP-seq
MIRT2206995	hsa-miR-4659b-3p	CLIP-seq
MIRT914884	hsa-miR-4670-3p	CLIP-seq
MIRT914885	hsa-miR-4685-5p	CLIP-seq
MIRT914887	hsa-miR-4705	CLIP-seq
MIRT914888	hsa-miR-4719	CLIP-seq
MIRT1971407	hsa-miR-4729	CLIP-seq
MIRT1547687	hsa-miR-4740-5p	CLIP-seq
MIRT914890	hsa-miR-4753-3p	CLIP-seq
MIRT1971408	hsa-miR-4755-5p	CLIP-seq
MIRT914891	hsa-miR-4758-5p	CLIP-seq
MIRT914892	hsa-miR-4760-3p	CLIP-seq
MIRT914893	hsa-miR-4765	CLIP-seq
MIRT914894	hsa-miR-4766-3p	CLIP-seq
MIRT2206996	hsa-miR-4768-5p	CLIP-seq
MIRT914896	hsa-miR-4769-5p	CLIP-seq
MIRT914897	hsa-miR-4781-3p	CLIP-seq
MIRT914898	hsa-miR-4799-5p	CLIP-seq
MIRT914899	hsa-miR-503	CLIP-seq
MIRT914900	hsa-miR-509-3-5p	CLIP-seq
MIRT914901	hsa-miR-509-5p	CLIP-seq
MIRT914902	hsa-miR-515-5p	CLIP-seq
MIRT914904	hsa-miR-532-5p	CLIP-seq
MIRT1971409	hsa-miR-544	CLIP-seq
MIRT914905	hsa-miR-548ag	CLIP-seq
MIRT914906	hsa-miR-548ai	CLIP-seq
MIRT914907	hsa-miR-548p	CLIP-seq
MIRT914908	hsa-miR-579	CLIP-seq
MIRT2206997	hsa-miR-614	CLIP-seq
MIRT2206998	hsa-miR-623	CLIP-seq
MIRT2206999	hsa-miR-626	CLIP-seq
MIRT1971410	hsa-miR-628-3p	CLIP-seq
MIRT914912	hsa-miR-659	CLIP-seq
MIRT914914	hsa-miR-664	CLIP-seq
MIRT914915	hsa-miR-766	CLIP-seq
MIRT914916	hsa-miR-769-5p	CLIP-seq
MIRT914917	hsa-miR-891b	CLIP-seq
MIRT914918	hsa-miR-9	CLIP-seq
MIRT2207000	hsa-miR-942	CLIP-seq
MIRT914919	hsa-miR-944	CLIP-seq
MIRT1547675	hsa-miR-1269	CLIP-seq
MIRT1547676	hsa-miR-1269b	CLIP-seq
MIRT914829	hsa-miR-1288	CLIP-seq
MIRT2386562	hsa-miR-197	CLIP-seq
MIRT2206979	hsa-miR-204	CLIP-seq
MIRT2206980	hsa-miR-211	CLIP-seq
MIRT1971395	hsa-miR-3130-3p	CLIP-seq
MIRT2386563	hsa-miR-3647-3p	CLIP-seq
MIRT2386564	hsa-miR-3690	CLIP-seq
MIRT2206984	hsa-miR-371-5p	CLIP-seq
MIRT2206985	hsa-miR-371b-5p	CLIP-seq
MIRT1547677	hsa-miR-378	CLIP-seq
MIRT1547678	hsa-miR-378b	CLIP-seq
MIRT1547679	hsa-miR-378c	CLIP-seq
MIRT1547680	hsa-miR-378d	CLIP-seq
MIRT1547681	hsa-miR-378e	CLIP-seq
MIRT1547682	hsa-miR-378f	CLIP-seq
MIRT1547683	hsa-miR-378h	CLIP-seq
MIRT1547684	hsa-miR-378i	CLIP-seq
MIRT2206986	hsa-miR-3938	CLIP-seq
MIRT1547685	hsa-miR-422a	CLIP-seq
MIRT1547686	hsa-miR-4515	CLIP-seq
MIRT914884	hsa-miR-4670-3p	CLIP-seq
MIRT1547687	hsa-miR-4740-5p	CLIP-seq
MIRT1971408	hsa-miR-4755-5p	CLIP-seq
MIRT2206996	hsa-miR-4768-5p	CLIP-seq
MIRT2206997	hsa-miR-614	CLIP-seq
MIRT2386565	hsa-miR-619	CLIP-seq
MIRT2206998	hsa-miR-623	CLIP-seq
MIRT2207000	hsa-miR-942	CLIP-seq
MIRT914826	hsa-miR-1225-3p	CLIP-seq
MIRT914827	hsa-miR-1234	CLIP-seq
MIRT1547675	hsa-miR-1269	CLIP-seq
MIRT1547676	hsa-miR-1269b	CLIP-seq
MIRT914828	hsa-miR-1285	CLIP-seq
MIRT914829	hsa-miR-1288	CLIP-seq
MIRT914830	hsa-miR-1292	CLIP-seq
MIRT914833	hsa-miR-141	CLIP-seq
MIRT2510192	hsa-miR-1470	CLIP-seq
MIRT2386562	hsa-miR-197	CLIP-seq
MIRT914836	hsa-miR-200a	CLIP-seq
MIRT914837	hsa-miR-2115	CLIP-seq
MIRT2510193	hsa-miR-2116	CLIP-seq
MIRT2206981	hsa-miR-2355-3p	CLIP-seq
MIRT914838	hsa-miR-299-3p	CLIP-seq
MIRT914842	hsa-miR-3145-3p	CLIP-seq
MIRT2510194	hsa-miR-3148	CLIP-seq
MIRT2206983	hsa-miR-3174	CLIP-seq
MIRT914844	hsa-miR-3180	CLIP-seq
MIRT914845	hsa-miR-3180-3p	CLIP-seq
MIRT914846	hsa-miR-3187-5p	CLIP-seq
MIRT914847	hsa-miR-3192	CLIP-seq
MIRT914848	hsa-miR-3196	CLIP-seq
MIRT914849	hsa-miR-3199	CLIP-seq
MIRT914850	hsa-miR-323-3p	CLIP-seq
MIRT2510195	hsa-miR-3613-3p	CLIP-seq
MIRT2386563	hsa-miR-3647-3p	CLIP-seq
MIRT2386564	hsa-miR-3690	CLIP-seq
MIRT1547677	hsa-miR-378	CLIP-seq
MIRT1547678	hsa-miR-378b	CLIP-seq
MIRT1547679	hsa-miR-378c	CLIP-seq
MIRT1547680	hsa-miR-378d	CLIP-seq
MIRT1547681	hsa-miR-378e	CLIP-seq
MIRT1547682	hsa-miR-378f	CLIP-seq
MIRT1547683	hsa-miR-378h	CLIP-seq
MIRT1547684	hsa-miR-378i	CLIP-seq
MIRT914857	hsa-miR-3925-3p	CLIP-seq
MIRT2510196	hsa-miR-3978	CLIP-seq
MIRT1547685	hsa-miR-422a	CLIP-seq
MIRT914858	hsa-miR-4261	CLIP-seq
MIRT914860	hsa-miR-4297	CLIP-seq
MIRT2206990	hsa-miR-4307	CLIP-seq
MIRT914861	hsa-miR-4314	CLIP-seq
MIRT2510197	hsa-miR-432	CLIP-seq
MIRT914862	hsa-miR-4320	CLIP-seq
MIRT914863	hsa-miR-4418	CLIP-seq
MIRT914865	hsa-miR-4433	CLIP-seq
MIRT914868	hsa-miR-4447	CLIP-seq
MIRT914869	hsa-miR-4459	CLIP-seq
MIRT914870	hsa-miR-4471	CLIP-seq
MIRT914871	hsa-miR-4472	CLIP-seq
MIRT914873	hsa-miR-4488	CLIP-seq
MIRT2510198	hsa-miR-4503	CLIP-seq
MIRT1547686	hsa-miR-4515	CLIP-seq
MIRT2206993	hsa-miR-4646-3p	CLIP-seq
MIRT914876	hsa-miR-4646-5p	CLIP-seq
MIRT914878	hsa-miR-4648	CLIP-seq
MIRT914879	hsa-miR-4651	CLIP-seq
MIRT914880	hsa-miR-4654	CLIP-seq
MIRT2510199	hsa-miR-4667-3p	CLIP-seq
MIRT2510200	hsa-miR-4677-5p	CLIP-seq
MIRT914885	hsa-miR-4685-5p	CLIP-seq
MIRT914886	hsa-miR-4697-5p	CLIP-seq
MIRT1547687	hsa-miR-4740-5p	CLIP-seq
MIRT914890	hsa-miR-4753-3p	CLIP-seq
MIRT914893	hsa-miR-4765	CLIP-seq
MIRT914895	hsa-miR-4768-3p	CLIP-seq
MIRT914896	hsa-miR-4769-5p	CLIP-seq
MIRT914900	hsa-miR-509-3-5p	CLIP-seq
MIRT914901	hsa-miR-509-5p	CLIP-seq
MIRT914902	hsa-miR-515-5p	CLIP-seq
MIRT914903	hsa-miR-516a-3p	CLIP-seq
MIRT2510201	hsa-miR-520a-5p	CLIP-seq
MIRT2510202	hsa-miR-525-5p	CLIP-seq
MIRT914904	hsa-miR-532-5p	CLIP-seq
MIRT914910	hsa-miR-608	CLIP-seq
MIRT914911	hsa-miR-612	CLIP-seq
MIRT2386565	hsa-miR-619	CLIP-seq
MIRT914912	hsa-miR-659	CLIP-seq
MIRT914913	hsa-miR-661	CLIP-seq
MIRT914915	hsa-miR-766	CLIP-seq
MIRT914916	hsa-miR-769-5p	CLIP-seq
MIRT914918	hsa-miR-9	CLIP-seq
MIRT914826	hsa-miR-1225-3p	CLIP-seq
MIRT914827	hsa-miR-1234	CLIP-seq
MIRT1547675	hsa-miR-1269	CLIP-seq
MIRT1547676	hsa-miR-1269b	CLIP-seq
MIRT914828	hsa-miR-1285	CLIP-seq
MIRT914829	hsa-miR-1288	CLIP-seq
MIRT914830	hsa-miR-1292	CLIP-seq
MIRT1971390	hsa-miR-133a	CLIP-seq
MIRT1971391	hsa-miR-133b	CLIP-seq
MIRT1971392	hsa-miR-140-3p	CLIP-seq
MIRT914833	hsa-miR-141	CLIP-seq
MIRT2510192	hsa-miR-1470	CLIP-seq
MIRT2386562	hsa-miR-197	CLIP-seq
MIRT914836	hsa-miR-200a	CLIP-seq
MIRT2510193	hsa-miR-2116	CLIP-seq
MIRT2206981	hsa-miR-2355-3p	CLIP-seq
MIRT914838	hsa-miR-299-3p	CLIP-seq
MIRT914842	hsa-miR-3145-3p	CLIP-seq
MIRT2510194	hsa-miR-3148	CLIP-seq
MIRT2206983	hsa-miR-3174	CLIP-seq
MIRT914844	hsa-miR-3180	CLIP-seq
MIRT914845	hsa-miR-3180-3p	CLIP-seq
MIRT914846	hsa-miR-3187-5p	CLIP-seq
MIRT914847	hsa-miR-3192	CLIP-seq
MIRT914848	hsa-miR-3196	CLIP-seq
MIRT914849	hsa-miR-3199	CLIP-seq
MIRT914850	hsa-miR-323-3p	CLIP-seq
MIRT2510195	hsa-miR-3613-3p	CLIP-seq
MIRT2386563	hsa-miR-3647-3p	CLIP-seq
MIRT2386564	hsa-miR-3690	CLIP-seq
MIRT1547677	hsa-miR-378	CLIP-seq
MIRT1547678	hsa-miR-378b	CLIP-seq
MIRT1547679	hsa-miR-378c	CLIP-seq
MIRT1547680	hsa-miR-378d	CLIP-seq
MIRT1547681	hsa-miR-378e	CLIP-seq
MIRT1547682	hsa-miR-378f	CLIP-seq
MIRT1547683	hsa-miR-378h	CLIP-seq
MIRT1547684	hsa-miR-378i	CLIP-seq
MIRT914857	hsa-miR-3925-3p	CLIP-seq
MIRT2510196	hsa-miR-3978	CLIP-seq
MIRT1547685	hsa-miR-422a	CLIP-seq
MIRT914858	hsa-miR-4261	CLIP-seq
MIRT914860	hsa-miR-4297	CLIP-seq
MIRT2206990	hsa-miR-4307	CLIP-seq
MIRT914861	hsa-miR-4314	CLIP-seq
MIRT2510197	hsa-miR-432	CLIP-seq
MIRT914862	hsa-miR-4320	CLIP-seq
MIRT914863	hsa-miR-4418	CLIP-seq
MIRT914865	hsa-miR-4433	CLIP-seq
MIRT914868	hsa-miR-4447	CLIP-seq
MIRT914869	hsa-miR-4459	CLIP-seq
MIRT914870	hsa-miR-4471	CLIP-seq
MIRT914871	hsa-miR-4472	CLIP-seq
MIRT914873	hsa-miR-4488	CLIP-seq
MIRT2510198	hsa-miR-4503	CLIP-seq
MIRT1547686	hsa-miR-4515	CLIP-seq
MIRT2206993	hsa-miR-4646-3p	CLIP-seq
MIRT914876	hsa-miR-4646-5p	CLIP-seq
MIRT914878	hsa-miR-4648	CLIP-seq
MIRT914879	hsa-miR-4651	CLIP-seq
MIRT914880	hsa-miR-4654	CLIP-seq
MIRT2510199	hsa-miR-4667-3p	CLIP-seq
MIRT2510200	hsa-miR-4677-5p	CLIP-seq
MIRT914885	hsa-miR-4685-5p	CLIP-seq
MIRT914886	hsa-miR-4697-5p	CLIP-seq
MIRT1971407	hsa-miR-4729	CLIP-seq
MIRT1547687	hsa-miR-4740-5p	CLIP-seq
MIRT914890	hsa-miR-4753-3p	CLIP-seq
MIRT914893	hsa-miR-4765	CLIP-seq
MIRT914895	hsa-miR-4768-3p	CLIP-seq
MIRT914896	hsa-miR-4769-5p	CLIP-seq
MIRT914900	hsa-miR-509-3-5p	CLIP-seq
MIRT914901	hsa-miR-509-5p	CLIP-seq
MIRT914902	hsa-miR-515-5p	CLIP-seq
MIRT2510201	hsa-miR-520a-5p	CLIP-seq
MIRT2510202	hsa-miR-525-5p	CLIP-seq
MIRT914904	hsa-miR-532-5p	CLIP-seq
MIRT914910	hsa-miR-608	CLIP-seq
MIRT914911	hsa-miR-612	CLIP-seq
MIRT2386565	hsa-miR-619	CLIP-seq
MIRT914912	hsa-miR-659	CLIP-seq
MIRT914913	hsa-miR-661	CLIP-seq
MIRT914915	hsa-miR-766	CLIP-seq
MIRT914916	hsa-miR-769-5p	CLIP-seq
MIRT914918	hsa-miR-9	CLIP-seq

Show/Hide all(53)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001541	Process	Ovarian follicle development	IEA
GO:0001669	Component	Acrosomal vesicle	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0005198	Function	Structural molecule activity	IEA
GO:0005515	Function	Protein binding	IPI	12477722, 15657067, 16212417, 17098867, 17620599, 18093941, 19016843, 20936779, 22750944, 23292143, 24189400, 24509793, 25241761, 25764135, 26496610, 28051089
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	TAS
GO:0005911	Component	Cell-cell junction	IDA	7650039, 10460003
GO:0005912	Component	Adherens junction	IBA	21873635
GO:0005915	Component	Zonula adherens	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0007015	Process	Actin filament organization	IEA
GO:0007155	Process	Cell adhesion	NAS	8323564
GO:0007163	Process	Establishment or maintenance of cell polarity	IEA
GO:0007406	Process	Negative regulation of neuroblast proliferation	IEA
GO:0007568	Process	Aging	IEA
GO:0008013	Function	Beta-catenin binding	IBA	21873635
GO:0008013	Function	Beta-catenin binding	IPI	7650039, 7890674
GO:0008584	Process	Male gonad development	IEA
GO:0014704	Component	Intercalated disc	IEA
GO:0015629	Component	Actin cytoskeleton	IEA
GO:0016264	Process	Gap junction assembly	IEA
GO:0016342	Component	Catenin complex	IBA	21873635
GO:0016342	Component	Catenin complex	IDA	7650039, 28051089
GO:0016477	Process	Cell migration	IBA	21873635
GO:0016600	Component	Flotillin complex	IEA
GO:0017166	Function	Vinculin binding	IPI	9700171
GO:0030027	Component	Lamellipodium	IEA
GO:0030054	Component	Cell junction	IDA
GO:0031103	Process	Axon regeneration	IEA
GO:0034332	Process	Adherens junction organization	TAS
GO:0034613	Process	Cellular protein localization	IEA
GO:0042475	Process	Odontogenesis of dentin-containing tooth	IEA
GO:0042802	Function	Identical protein binding	IPI	23292143
GO:0043231	Component	Intracellular membrane-bounded organelle	IDA
GO:0043297	Process	Apical junction assembly	NAS	9700171
GO:0043627	Process	Response to estrogen	IEA
GO:0045295	Function	Gamma-catenin binding	IPI	7650039, 7890674
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0045296	Function	Cadherin binding	IPI	7650039, 12734196
GO:0045880	Process	Positive regulation of smoothened signaling pathway	IEA
GO:0051015	Function	Actin filament binding	IBA	21873635
GO:0051015	Function	Actin filament binding	IEA
GO:0051149	Process	Positive regulation of muscle cell differentiation	TAS
GO:0071681	Process	Cellular response to indole-3-methanol	IDA	10868478
GO:0090136	Process	Epithelial cell-cell adhesion	IEA
GO:0098609	Process	Cell-cell adhesion	IBA	21873635
GO:1900181	Process	Negative regulation of protein localization to nucleus	ISS
GO:2000146	Process	Negative regulation of cell motility	IEA
GO:2001045	Process	Negative regulation of integrin-mediated signaling pathway	IEA
GO:2001240	Process	Negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	IEA
GO:2001241	Process	Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	IEA

MIM	HGNC	e!Ensembl
116805	2509	ENSG00000044115

Protein

UniProt ID

P35221

Protein name

Catenin alpha-1 (Alpha E-catenin) (Cadherin-associated protein) (Renal carcinoma antigen NY-REN-13)

Protein function

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion

PDB

1H6G , 4EHP , 4IGG , 6UPV , 6V2O , 6V2P , 7UTJ , 9BL2 , 9BL3 , 9BL4

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01044	Vinculin	19 → 339	Vinculin family	Family
PF01044	Vinculin	333 → 867	Vinculin family	Family

Sequence

MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHV
LAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVK
RGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL
KPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKAN
RDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEER
FRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKER
SDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYA
QVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLA
QENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDR
TAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSS
DPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTED
DQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMC
MIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYL
QRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVAS
TKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEF
KAMDSI

Sequence length

906

Interactions

View interactions

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