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CCNA1 (cyclin A1)
Gene
Gene SNPs Transcription factors Other IDs
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8900
Gene nameGene Name - the full gene name approved by the HGNC.
Cyclin A1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CCNA1
SynonymsGene synonyms aliases
CT146
ChromosomeChromosome number
13
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
13q13.3
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit
miRNAmiRNA information provided by mirtarbase database.
Gene SNPs Transcription factors Other IDs
miRTarBase ID miRNA Experiments Reference
MIRT006767 hsa-miR-372-3p FACS, GFP reporter assay, qRT-PCR, Western blot 21646351
MIRT006767 hsa-miR-372-3p FACS, GFP reporter assay, qRT-PCR, Western blot 21646351
MIRT018229 hsa-miR-335-5p Microarray 18185580
MIRT022823 hsa-miR-124-3p Microarray 18668037
MIRT032444 hsa-let-7b-5p Reporter assay 18379589
Transcription factors
Gene SNPs Transcription factors Other IDs
Transcription factor Regulation Reference
ATF1 Repression 12044952
CREM Unknown 7760825
KDM4B Unknown 20682797
MYB Activation 10590070
MYBL2 Unknown 11264176;15922873
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene SNPs Transcription factors Other IDs
GO ID Ontology Definition Evidence Reference
GO:0000079 Process Regulation of cyclin-dependent protein serine/threonine kinase activity IBA 21873635
GO:0000083 Process Regulation of transcription involved in G1/S transition of mitotic cell cycle TAS
GO:0000307 Component Cyclin-dependent protein kinase holoenzyme complex IBA 21873635
GO:0005515 Function Protein binding IPI 8756624, 15159402, 15232106, 18692475, 21540187, 25241761, 29997244, 32814053
GO:0005634 Component Nucleus IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene SNPs Transcription factors Other IDs
MIM
HGNC
e!Ensembl
Protein
Gene SNPs Transcription factors Other IDs
UniProt ID P78396
Protein name Cyclin-A1
Protein function May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic c
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00134 Cyclin_N
214 → 340
Cyclin, N-terminal domain
 Domain
PF02984 Cyclin_C
342 → 459
Cyclin, C-terminal domain
 Domain
Sequence 
METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA
RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK
ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN
TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT
EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY
EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR
TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV
PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
Sequence length 465
Interactions View interactions

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