GediPNet logo

CALML5 (calmodulin like 5)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51806
Gene nameGene Name - the full gene name approved by the HGNC.
Calmodulin like 5
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CALML5
SynonymsGene synonyms aliases
CLSP
ChromosomeChromosome number
10
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10p15.1
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008]
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT018952 hsa-miR-335-5p Microarray 18185580
MIRT021412 hsa-miR-9-5p Microarray 17612493
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005509 Function Calcium ion binding IBA 21873635
GO:0005576 Component Extracellular region TAS
GO:0007165 Process Signal transduction TAS 10777582
GO:0008544 Process Epidermis development TAS 10777582
GO:0030234 Function Enzyme regulator activity IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q9NZT1
Protein name Calmodulin-like protein 5 (Calmodulin-like skin protein)
Protein function Binds calcium. May be involved in terminal differentiation of keratinocytes.
PDB 2B1U
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13499 EF-hand_7
10 74
EF-hand domain pair
Domain
PF00036 EF-hand_1
12 40
EF hand
Domain
PF13499 EF-hand_7
80 144
EF-hand domain pair
Domain
PF13833 EF-hand_8
95 146
EF-hand domain pair
Domain
Sequence
Sequence length 146
Interactions View interactions

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412