CALML3 (calmodulin like 3)

Gene

• Entrez ID: 810
• Gene name: Calmodulin like 3
• Gene symbol: CALML3
• Synonyms: CLP
• Chromosome: 10
• Chromosome location: 10p15.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT489704	hsa-miR-4665-5p	PAR-CLIP	23592263
MIRT489705	hsa-miR-1275	PAR-CLIP	23592263
MIRT489706	hsa-miR-5010-5p	PAR-CLIP	23592263
MIRT489707	hsa-miR-4525	PAR-CLIP	23592263
MIRT489708	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT489709	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT489710	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT489711	hsa-miR-5698	PAR-CLIP	23592263
MIRT489712	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT489713	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT489714	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT489715	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT489716	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT489717	hsa-miR-765	PAR-CLIP	23592263
MIRT489718	hsa-miR-6722-3p	PAR-CLIP	23592263
MIRT489719	hsa-miR-1909-3p	PAR-CLIP	23592263
MIRT489720	hsa-miR-6087	PAR-CLIP	23592263
MIRT489721	hsa-miR-6798-5p	PAR-CLIP	23592263
MIRT489722	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT489723	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT489724	hsa-miR-940	PAR-CLIP	23592263
MIRT489725	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT489726	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT489727	hsa-miR-4695-5p	PAR-CLIP	23592263

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IBA	21873635
GO:0005515	Function	Protein binding	IPI	16189514, 18570893, 21044950, 25416956, 32296183
GO:0030234	Function	Enzyme regulator activity	IBA	21873635
GO:0050790	Process	Regulation of catalytic activity	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867

Other IDs

• MIM: 114184
• HGNC: 1452
• e!Ensembl: ENSG00000178363

Protein

• UniProt ID: P27482
• Protein name: Calmodulin-like protein 3 (CaM-like protein) (CLP) (Calmodulin-related protein NB-1)
• Protein function: May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates.
• PDB: 1GGZ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00036	EF-hand_1	12 → 40	EF hand	Domain
  PF00036	EF-hand_1	48 → 76	EF hand	Domain
  PF00036	EF-hand_1	85 → 113	EF hand	Domain
  PF00036	EF-hand_1	121 → 149	EF hand	Domain

• Sequence:

  MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG
  NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE
  EVDEMIRAADTDGDGQVNYEEFVRVLVSK

• Sequence length: 149