CACNG7 (calcium voltage-gated channel auxiliary subunit gamma 7)

Gene

• Entrez ID: 59284
• Gene name: Calcium voltage-gated channel auxiliary subunit gamma 7
• Gene symbol: CACNG7
• Synonyms: -
• Chromosome: 19
• Chromosome location: 19q13.42
• Summary: The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of th

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT508852	hsa-miR-224-5p	PAR-CLIP	20371350
MIRT508851	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT508850	hsa-miR-1272	PAR-CLIP	20371350
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT508848	hsa-miR-3161	PAR-CLIP	20371350
MIRT508847	hsa-miR-599	PAR-CLIP	20371350
MIRT508852	hsa-miR-224-5p	PAR-CLIP	20371350
MIRT508851	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT508850	hsa-miR-1272	PAR-CLIP	20371350
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT508848	hsa-miR-3161	PAR-CLIP	20371350
MIRT508847	hsa-miR-599	PAR-CLIP	20371350
MIRT560196	hsa-miR-3173-3p	PAR-CLIP	20371350
MIRT560195	hsa-miR-6891-5p	PAR-CLIP	20371350
MIRT560194	hsa-miR-4786-3p	PAR-CLIP	20371350
MIRT560193	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT560192	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT560191	hsa-miR-765	PAR-CLIP	20371350
MIRT508852	hsa-miR-224-5p	PAR-CLIP	22012620
MIRT508851	hsa-miR-580-5p	PAR-CLIP	22012620
MIRT508850	hsa-miR-1272	PAR-CLIP	22012620
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	22012620
MIRT508848	hsa-miR-3161	PAR-CLIP	22012620
MIRT508847	hsa-miR-599	PAR-CLIP	22012620
MIRT508852	hsa-miR-224-5p	PAR-CLIP	23446348
MIRT508851	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT508850	hsa-miR-1272	PAR-CLIP	23446348
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT508848	hsa-miR-3161	PAR-CLIP	23446348
MIRT508847	hsa-miR-599	PAR-CLIP	23446348
MIRT508852	hsa-miR-224-5p	PAR-CLIP	23446348
MIRT508851	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT508850	hsa-miR-1272	PAR-CLIP	23446348
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT508848	hsa-miR-3161	PAR-CLIP	23446348
MIRT508847	hsa-miR-599	PAR-CLIP	23446348
MIRT508852	hsa-miR-224-5p	PAR-CLIP	20371350
MIRT508851	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT508850	hsa-miR-1272	PAR-CLIP	20371350
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT508848	hsa-miR-3161	PAR-CLIP	20371350
MIRT508847	hsa-miR-599	PAR-CLIP	20371350
MIRT508852	hsa-miR-224-5p	PAR-CLIP	20371350
MIRT508851	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT508850	hsa-miR-1272	PAR-CLIP	20371350
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT508848	hsa-miR-3161	PAR-CLIP	20371350
MIRT508847	hsa-miR-599	PAR-CLIP	20371350
MIRT560196	hsa-miR-3173-3p	PAR-CLIP	20371350
MIRT560195	hsa-miR-6891-5p	PAR-CLIP	20371350
MIRT560194	hsa-miR-4786-3p	PAR-CLIP	20371350
MIRT560193	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT560192	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT560191	hsa-miR-765	PAR-CLIP	20371350
MIRT508852	hsa-miR-224-5p	PAR-CLIP	22012620
MIRT508851	hsa-miR-580-5p	PAR-CLIP	22012620
MIRT508850	hsa-miR-1272	PAR-CLIP	22012620
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	22012620
MIRT508848	hsa-miR-3161	PAR-CLIP	22012620
MIRT508847	hsa-miR-599	PAR-CLIP	22012620
MIRT508852	hsa-miR-224-5p	PAR-CLIP	23446348
MIRT508851	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT508850	hsa-miR-1272	PAR-CLIP	23446348
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT508848	hsa-miR-3161	PAR-CLIP	23446348
MIRT508847	hsa-miR-599	PAR-CLIP	23446348
MIRT508852	hsa-miR-224-5p	PAR-CLIP	23446348
MIRT508851	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT508850	hsa-miR-1272	PAR-CLIP	23446348
MIRT508849	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT508848	hsa-miR-3161	PAR-CLIP	23446348
MIRT508847	hsa-miR-599	PAR-CLIP	23446348
MIRT858222	hsa-miR-1276	CLIP-seq
MIRT858223	hsa-miR-1913	CLIP-seq
MIRT858224	hsa-miR-3125	CLIP-seq
MIRT858225	hsa-miR-3184	CLIP-seq
MIRT858226	hsa-miR-324-3p	CLIP-seq
MIRT858227	hsa-miR-331-3p	CLIP-seq
MIRT858228	hsa-miR-3714	CLIP-seq
MIRT858229	hsa-miR-3916	CLIP-seq
MIRT858230	hsa-miR-3943	CLIP-seq
MIRT858231	hsa-miR-423-5p	CLIP-seq
MIRT858232	hsa-miR-4313	CLIP-seq
MIRT858233	hsa-miR-4532	CLIP-seq
MIRT858234	hsa-miR-4640-5p	CLIP-seq
MIRT858235	hsa-miR-4726-5p	CLIP-seq
MIRT858236	hsa-miR-4736	CLIP-seq
MIRT858237	hsa-miR-4779	CLIP-seq
MIRT858238	hsa-miR-548an	CLIP-seq
MIRT858239	hsa-miR-7	CLIP-seq
MIRT858240	hsa-miR-940	CLIP-seq
MIRT1954868	hsa-miR-3175	CLIP-seq
MIRT858228	hsa-miR-3714	CLIP-seq
MIRT858230	hsa-miR-3943	CLIP-seq
MIRT1954869	hsa-miR-4300	CLIP-seq
MIRT858232	hsa-miR-4313	CLIP-seq
MIRT858236	hsa-miR-4736	CLIP-seq
MIRT858238	hsa-miR-548an	CLIP-seq
MIRT1954870	hsa-miR-920	CLIP-seq
MIRT858240	hsa-miR-940	CLIP-seq
MIRT2192440	hsa-miR-214	CLIP-seq
MIRT2192441	hsa-miR-3619-5p	CLIP-seq
MIRT858228	hsa-miR-3714	CLIP-seq
MIRT858230	hsa-miR-3943	CLIP-seq
MIRT858232	hsa-miR-4313	CLIP-seq
MIRT2192442	hsa-miR-4530	CLIP-seq
MIRT858236	hsa-miR-4736	CLIP-seq
MIRT858238	hsa-miR-548an	CLIP-seq
MIRT2192443	hsa-miR-761	CLIP-seq
MIRT858240	hsa-miR-940	CLIP-seq
MIRT2436037	hsa-miR-3621	CLIP-seq
MIRT2436038	hsa-miR-3656	CLIP-seq
MIRT2677209	hsa-miR-142-5p	CLIP-seq
MIRT2677210	hsa-miR-203	CLIP-seq
MIRT2677211	hsa-miR-561	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005245	Function	Voltage-gated calcium channel activity	IBA	21873635
GO:0005245	Function	Voltage-gated calcium channel activity	NAS	11170751
GO:0005246	Function	Calcium channel regulator activity	IDA	21127204
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005769	Component	Early endosome	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005891	Component	Voltage-gated calcium channel complex	NAS	11170751
GO:0006816	Process	Calcium ion transport	NAS	11170751
GO:0016247	Function	Channel regulator activity	IBA	21873635
GO:0019226	Process	Transmission of nerve impulse	IBA	21873635
GO:0032281	Component	AMPA glutamate receptor complex	IBA	21873635
GO:0032281	Component	AMPA glutamate receptor complex	ISS
GO:0043025	Component	Neuronal cell body	IEA
GO:0043488	Process	Regulation of mRNA stability	IEA
GO:0044300	Component	Cerebellar mossy fiber	IEA
GO:0051968	Process	Positive regulation of synaptic transmission, glutamatergic	IBA	21873635
GO:0061337	Process	Cardiac conduction	TAS
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0098839	Component	Postsynaptic density membrane	IBA	21873635
GO:0098943	Process	Neurotransmitter receptor transport, postsynaptic endosome to lysosome	IBA	21873635
GO:0098970	Process	Postsynaptic neurotransmitter receptor diffusion trapping	IBA	21873635
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099061	Component	Integral component of postsynaptic density membrane	IEA
GO:0099590	Process	Neurotransmitter receptor internalization	IBA	21873635
GO:1903861	Process	Positive regulation of dendrite extension	IEA
GO:1990454	Component	L-type voltage-gated calcium channel complex	IDA	21127204
GO:2000311	Process	Regulation of AMPA receptor activity	IBA	21873635
GO:2000311	Process	Regulation of AMPA receptor activity	IDA	21172611

Other IDs

• MIM: 606899
• HGNC: 13626
• e!Ensembl: ENSG00000105605

Protein

• UniProt ID: P62955
• Protein name: Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage-gated calcium channel gamma-7 subunit) (Transmembrane AMPAR regulatory protein gamma-7) (TARP gamma-7)
• Protein function: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (PubMed:21127204). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cel
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13903	Claudin_2	18 → 197	PMP-22/EMP/MP20/Claudin tight junction	Family

• Sequence:

  MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR
  VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI
  GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA
  FAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRG
  RSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC

• Sequence length: 275