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ATP1B3 (ATPase Na+/K+ transporting subunit beta 3)

Gene

483

ATPase Na+/K+ transporting subunit beta 3

ATP1B3

ATPB-3, CD298

3q23

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemica

Show/Hide all(277)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025733	hsa-miR-7-5p	Microarray	19073608
MIRT048487	hsa-miR-100-5p	CLASH	23622248
MIRT045107	hsa-miR-186-5p	CLASH	23622248
MIRT036767	hsa-miR-760	CLASH	23622248
MIRT705414	hsa-miR-1197	HITS-CLIP	23313552
MIRT705413	hsa-miR-1273d	HITS-CLIP	23313552
MIRT705412	hsa-miR-513b-3p	HITS-CLIP	23313552
MIRT705411	hsa-miR-5571-5p	HITS-CLIP	23313552
MIRT705410	hsa-miR-329-3p	HITS-CLIP	23313552
MIRT705409	hsa-miR-362-3p	HITS-CLIP	23313552
MIRT705408	hsa-miR-6757-3p	HITS-CLIP	23313552
MIRT705407	hsa-miR-4724-5p	HITS-CLIP	23313552
MIRT705406	hsa-miR-4436b-3p	HITS-CLIP	23313552
MIRT705405	hsa-miR-4632-5p	HITS-CLIP	23313552
MIRT705404	hsa-miR-6735-5p	HITS-CLIP	23313552
MIRT705403	hsa-miR-6879-5p	HITS-CLIP	23313552
MIRT705402	hsa-miR-7843-5p	HITS-CLIP	23313552
MIRT305201	hsa-miR-1272	HITS-CLIP	23313552
MIRT305202	hsa-miR-1322	HITS-CLIP	23313552
MIRT705401	hsa-miR-379-3p	HITS-CLIP	23313552
MIRT705400	hsa-miR-411-3p	HITS-CLIP	23313552
MIRT705399	hsa-miR-4761-5p	HITS-CLIP	23313552
MIRT705398	hsa-miR-1228-3p	HITS-CLIP	23313552
MIRT705397	hsa-miR-6847-5p	HITS-CLIP	23313552
MIRT705396	hsa-miR-4257	HITS-CLIP	23313552
MIRT705395	hsa-miR-922	HITS-CLIP	23313552
MIRT705394	hsa-miR-4514	HITS-CLIP	23313552
MIRT705393	hsa-miR-4692	HITS-CLIP	23313552
MIRT705392	hsa-miR-935	HITS-CLIP	23313552
MIRT705391	hsa-miR-519d-5p	HITS-CLIP	23313552
MIRT705390	hsa-miR-5695	HITS-CLIP	23313552
MIRT705389	hsa-miR-875-3p	HITS-CLIP	23313552
MIRT705388	hsa-miR-6128	HITS-CLIP	23313552
MIRT705387	hsa-miR-3171	HITS-CLIP	23313552
MIRT705386	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT305204	hsa-miR-6828-5p	HITS-CLIP	23313552
MIRT705385	hsa-miR-671-5p	HITS-CLIP	23313552
MIRT705384	hsa-miR-196a-3p	HITS-CLIP	23313552
MIRT705383	hsa-miR-548au-3p	HITS-CLIP	23313552
MIRT705382	hsa-miR-323a-5p	HITS-CLIP	23313552
MIRT705381	hsa-miR-3682-5p	HITS-CLIP	23313552
MIRT705380	hsa-miR-6516-3p	HITS-CLIP	23313552
MIRT705379	hsa-miR-515-5p	HITS-CLIP	23313552
MIRT705378	hsa-miR-519e-5p	HITS-CLIP	23313552
MIRT705377	hsa-miR-1299	HITS-CLIP	23313552
MIRT305203	hsa-miR-6079	HITS-CLIP	23313552
MIRT705376	hsa-miR-6843-3p	HITS-CLIP	23313552
MIRT705375	hsa-miR-6848-3p	HITS-CLIP	23313552
MIRT705374	hsa-miR-629-3p	HITS-CLIP	23313552
MIRT705373	hsa-miR-4688	HITS-CLIP	23313552
MIRT705372	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT705371	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT705370	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT705369	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT705368	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT705367	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT705366	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT705365	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT705364	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT705363	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT705362	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT705361	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT705360	hsa-miR-302e	HITS-CLIP	23313552
MIRT705359	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT705358	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT705357	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT705356	hsa-miR-520b	HITS-CLIP	23313552
MIRT705355	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT705354	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT705353	hsa-miR-520e	HITS-CLIP	23313552
MIRT705352	hsa-miR-4438	HITS-CLIP	23313552
MIRT705351	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT705350	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT705349	hsa-miR-520h	HITS-CLIP	23313552
MIRT705348	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT705347	hsa-miR-1234-3p	HITS-CLIP	23313552
MIRT705346	hsa-miR-7107-5p	HITS-CLIP	23313552
MIRT705345	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT705344	hsa-miR-4707-3p	HITS-CLIP	23313552
MIRT705343	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT705342	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT705341	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT705340	hsa-miR-3199	HITS-CLIP	23313552
MIRT705339	hsa-miR-8052	HITS-CLIP	23313552
MIRT705338	hsa-miR-365a-5p	HITS-CLIP	23313552
MIRT705337	hsa-miR-365b-5p	HITS-CLIP	23313552
MIRT705336	hsa-miR-5095	HITS-CLIP	23313552
MIRT705335	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT705334	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT705414	hsa-miR-1197	HITS-CLIP	23313552
MIRT705413	hsa-miR-1273d	HITS-CLIP	23313552
MIRT705412	hsa-miR-513b-3p	HITS-CLIP	23313552
MIRT705411	hsa-miR-5571-5p	HITS-CLIP	23313552
MIRT705410	hsa-miR-329-3p	HITS-CLIP	23313552
MIRT705409	hsa-miR-362-3p	HITS-CLIP	23313552
MIRT705408	hsa-miR-6757-3p	HITS-CLIP	23313552
MIRT705407	hsa-miR-4724-5p	HITS-CLIP	23313552
MIRT705406	hsa-miR-4436b-3p	HITS-CLIP	23313552
MIRT705405	hsa-miR-4632-5p	HITS-CLIP	23313552
MIRT705404	hsa-miR-6735-5p	HITS-CLIP	23313552
MIRT705403	hsa-miR-6879-5p	HITS-CLIP	23313552
MIRT705402	hsa-miR-7843-5p	HITS-CLIP	23313552
MIRT305201	hsa-miR-1272	HITS-CLIP	23313552
MIRT305202	hsa-miR-1322	HITS-CLIP	23313552
MIRT705401	hsa-miR-379-3p	HITS-CLIP	23313552
MIRT705400	hsa-miR-411-3p	HITS-CLIP	23313552
MIRT705399	hsa-miR-4761-5p	HITS-CLIP	23313552
MIRT705398	hsa-miR-1228-3p	HITS-CLIP	23313552
MIRT705397	hsa-miR-6847-5p	HITS-CLIP	23313552
MIRT705396	hsa-miR-4257	HITS-CLIP	23313552
MIRT705395	hsa-miR-922	HITS-CLIP	23313552
MIRT705394	hsa-miR-4514	HITS-CLIP	23313552
MIRT705393	hsa-miR-4692	HITS-CLIP	23313552
MIRT705392	hsa-miR-935	HITS-CLIP	23313552
MIRT705391	hsa-miR-519d-5p	HITS-CLIP	23313552
MIRT705390	hsa-miR-5695	HITS-CLIP	23313552
MIRT705389	hsa-miR-875-3p	HITS-CLIP	23313552
MIRT705388	hsa-miR-6128	HITS-CLIP	23313552
MIRT705387	hsa-miR-3171	HITS-CLIP	23313552
MIRT705386	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT305204	hsa-miR-6828-5p	HITS-CLIP	23313552
MIRT705385	hsa-miR-671-5p	HITS-CLIP	23313552
MIRT705384	hsa-miR-196a-3p	HITS-CLIP	23313552
MIRT705383	hsa-miR-548au-3p	HITS-CLIP	23313552
MIRT705382	hsa-miR-323a-5p	HITS-CLIP	23313552
MIRT705381	hsa-miR-3682-5p	HITS-CLIP	23313552
MIRT705380	hsa-miR-6516-3p	HITS-CLIP	23313552
MIRT705379	hsa-miR-515-5p	HITS-CLIP	23313552
MIRT705378	hsa-miR-519e-5p	HITS-CLIP	23313552
MIRT705377	hsa-miR-1299	HITS-CLIP	23313552
MIRT305203	hsa-miR-6079	HITS-CLIP	23313552
MIRT705376	hsa-miR-6843-3p	HITS-CLIP	23313552
MIRT705375	hsa-miR-6848-3p	HITS-CLIP	23313552
MIRT705374	hsa-miR-629-3p	HITS-CLIP	23313552
MIRT705373	hsa-miR-4688	HITS-CLIP	23313552
MIRT705372	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT705371	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT705370	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT705369	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT705368	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT705367	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT705366	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT705365	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT705364	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT705363	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT705362	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT705361	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT705360	hsa-miR-302e	HITS-CLIP	23313552
MIRT705359	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT705358	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT705357	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT705356	hsa-miR-520b	HITS-CLIP	23313552
MIRT705355	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT705354	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT705353	hsa-miR-520e	HITS-CLIP	23313552
MIRT705352	hsa-miR-4438	HITS-CLIP	23313552
MIRT705351	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT705350	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT705349	hsa-miR-520h	HITS-CLIP	23313552
MIRT705348	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT705347	hsa-miR-1234-3p	HITS-CLIP	23313552
MIRT705346	hsa-miR-7107-5p	HITS-CLIP	23313552
MIRT705345	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT705344	hsa-miR-4707-3p	HITS-CLIP	23313552
MIRT705343	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT705342	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT705341	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT705340	hsa-miR-3199	HITS-CLIP	23313552
MIRT705339	hsa-miR-8052	HITS-CLIP	23313552
MIRT705338	hsa-miR-365a-5p	HITS-CLIP	23313552
MIRT705337	hsa-miR-365b-5p	HITS-CLIP	23313552
MIRT705336	hsa-miR-5095	HITS-CLIP	23313552
MIRT705335	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT705334	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT807126	hsa-miR-1273	CLIP-seq
MIRT807127	hsa-miR-1301	CLIP-seq
MIRT807128	hsa-miR-140-3p	CLIP-seq
MIRT807129	hsa-miR-142-5p	CLIP-seq
MIRT807130	hsa-miR-182	CLIP-seq
MIRT807131	hsa-miR-224	CLIP-seq
MIRT807132	hsa-miR-2682	CLIP-seq
MIRT807133	hsa-miR-3126-3p	CLIP-seq
MIRT807134	hsa-miR-3163	CLIP-seq
MIRT807135	hsa-miR-3177-3p	CLIP-seq
MIRT807136	hsa-miR-340	CLIP-seq
MIRT807137	hsa-miR-3614-5p	CLIP-seq
MIRT807138	hsa-miR-3667-5p	CLIP-seq
MIRT807139	hsa-miR-376c	CLIP-seq
MIRT807140	hsa-miR-4477a	CLIP-seq
MIRT807141	hsa-miR-449c	CLIP-seq
MIRT807142	hsa-miR-4660	CLIP-seq
MIRT807143	hsa-miR-4699-3p	CLIP-seq
MIRT807144	hsa-miR-4743	CLIP-seq
MIRT807145	hsa-miR-4746-5p	CLIP-seq
MIRT807146	hsa-miR-4781-3p	CLIP-seq
MIRT807147	hsa-miR-5047	CLIP-seq
MIRT807148	hsa-miR-578	CLIP-seq
MIRT807149	hsa-miR-583	CLIP-seq
MIRT1938373	hsa-miR-125a-3p	CLIP-seq
MIRT807126	hsa-miR-1273	CLIP-seq
MIRT807129	hsa-miR-142-5p	CLIP-seq
MIRT807130	hsa-miR-182	CLIP-seq
MIRT807131	hsa-miR-224	CLIP-seq
MIRT807132	hsa-miR-2682	CLIP-seq
MIRT807133	hsa-miR-3126-3p	CLIP-seq
MIRT807135	hsa-miR-3177-3p	CLIP-seq
MIRT807136	hsa-miR-340	CLIP-seq
MIRT807137	hsa-miR-3614-5p	CLIP-seq
MIRT807138	hsa-miR-3667-5p	CLIP-seq
MIRT807139	hsa-miR-376c	CLIP-seq
MIRT1938374	hsa-miR-3934	CLIP-seq
MIRT807141	hsa-miR-449c	CLIP-seq
MIRT807143	hsa-miR-4699-3p	CLIP-seq
MIRT807145	hsa-miR-4746-5p	CLIP-seq
MIRT807146	hsa-miR-4781-3p	CLIP-seq
MIRT807149	hsa-miR-583	CLIP-seq
MIRT1938375	hsa-miR-764	CLIP-seq
MIRT807126	hsa-miR-1273	CLIP-seq
MIRT807129	hsa-miR-142-5p	CLIP-seq
MIRT807130	hsa-miR-182	CLIP-seq
MIRT2177738	hsa-miR-188-5p	CLIP-seq
MIRT807131	hsa-miR-224	CLIP-seq
MIRT807132	hsa-miR-2682	CLIP-seq
MIRT807133	hsa-miR-3126-3p	CLIP-seq
MIRT2177739	hsa-miR-3202	CLIP-seq
MIRT807136	hsa-miR-340	CLIP-seq
MIRT807137	hsa-miR-3614-5p	CLIP-seq
MIRT2177740	hsa-miR-3646	CLIP-seq
MIRT2177741	hsa-miR-3662	CLIP-seq
MIRT2177742	hsa-miR-3664-5p	CLIP-seq
MIRT807139	hsa-miR-376c	CLIP-seq
MIRT807141	hsa-miR-449c	CLIP-seq
MIRT2177743	hsa-miR-4533	CLIP-seq
MIRT2177744	hsa-miR-4698	CLIP-seq
MIRT807143	hsa-miR-4699-3p	CLIP-seq
MIRT807144	hsa-miR-4743	CLIP-seq
MIRT807146	hsa-miR-4781-3p	CLIP-seq
MIRT2177745	hsa-miR-493	CLIP-seq
MIRT2177746	hsa-miR-520d-5p	CLIP-seq
MIRT2177747	hsa-miR-524-5p	CLIP-seq
MIRT2177748	hsa-miR-548a-3p	CLIP-seq
MIRT2177749	hsa-miR-548e	CLIP-seq
MIRT2177750	hsa-miR-548f	CLIP-seq
MIRT2177751	hsa-miR-622	CLIP-seq
MIRT2177752	hsa-miR-802	CLIP-seq
MIRT807127	hsa-miR-1301	CLIP-seq
MIRT807129	hsa-miR-142-5p	CLIP-seq
MIRT807131	hsa-miR-224	CLIP-seq
MIRT807136	hsa-miR-340	CLIP-seq
MIRT807137	hsa-miR-3614-5p	CLIP-seq
MIRT807142	hsa-miR-4660	CLIP-seq
MIRT807147	hsa-miR-5047	CLIP-seq
MIRT2177742	hsa-miR-3664-5p	CLIP-seq
MIRT807143	hsa-miR-4699-3p	CLIP-seq
MIRT2435572	hsa-miR-4714-5p	CLIP-seq
MIRT2481104	hsa-miR-1270	CLIP-seq
MIRT807134	hsa-miR-3163	CLIP-seq
MIRT807135	hsa-miR-3177-3p	CLIP-seq
MIRT2177742	hsa-miR-3664-5p	CLIP-seq
MIRT807139	hsa-miR-376c	CLIP-seq
MIRT807140	hsa-miR-4477a	CLIP-seq
MIRT2481105	hsa-miR-4645-3p	CLIP-seq
MIRT2481106	hsa-miR-4683	CLIP-seq
MIRT807143	hsa-miR-4699-3p	CLIP-seq
MIRT2435572	hsa-miR-4714-5p	CLIP-seq
MIRT2481107	hsa-miR-620	CLIP-seq
MIRT2481104	hsa-miR-1270	CLIP-seq
MIRT807134	hsa-miR-3163	CLIP-seq
MIRT807135	hsa-miR-3177-3p	CLIP-seq
MIRT2177742	hsa-miR-3664-5p	CLIP-seq
MIRT807139	hsa-miR-376c	CLIP-seq
MIRT807140	hsa-miR-4477a	CLIP-seq
MIRT2481105	hsa-miR-4645-3p	CLIP-seq
MIRT2481106	hsa-miR-4683	CLIP-seq
MIRT807143	hsa-miR-4699-3p	CLIP-seq
MIRT2435572	hsa-miR-4714-5p	CLIP-seq
MIRT2481107	hsa-miR-620	CLIP-seq

Show/Hide all(36)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001671	Function	ATPase activator activity	IBA	21873635
GO:0001671	Function	ATPase activator activity	IDA	10636900, 19542013
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IDA	18522992
GO:0005886	Component	Plasma membrane	TAS
GO:0005890	Component	Sodium:potassium-exchanging ATPase complex	IBA	21873635
GO:0005890	Component	Sodium:potassium-exchanging ATPase complex	IDA	10636900, 19542013
GO:0005890	Component	Sodium:potassium-exchanging ATPase complex	IPI	16861705
GO:0005901	Component	Caveola	IEA
GO:0006883	Process	Cellular sodium ion homeostasis	IBA	21873635
GO:0006883	Process	Cellular sodium ion homeostasis	IDA	10636900, 19542013
GO:0010248	Process	Establishment or maintenance of transmembrane electrochemical gradient	IEA
GO:0030007	Process	Cellular potassium ion homeostasis	IBA	21873635
GO:0030007	Process	Cellular potassium ion homeostasis	IDA	10636900, 19542013
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	10636900, 19542013
GO:0030674	Function	Protein-macromolecule adaptor activity	IGI	16861705
GO:0032781	Process	Positive regulation of ATPase activity	IDA	10636900
GO:0034220	Process	Ion transmembrane transport	TAS
GO:0035725	Process	Sodium ion transmembrane transport	IGI	16861705
GO:0036126	Component	Sperm flagellum	IDA	16861705
GO:0036376	Process	Sodium ion export across plasma membrane	IBA	21873635
GO:0036376	Process	Sodium ion export across plasma membrane	IDA	10636900, 19542013
GO:0042470	Component	Melanosome	IEA
GO:0050821	Process	Protein stabilization	IDA	10636900
GO:0050900	Process	Leukocyte migration	TAS
GO:0051117	Function	ATPase binding	IPI	10636900, 16861705
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:0071805	Process	Potassium ion transmembrane transport	IGI	16861705
GO:0072659	Process	Protein localization to plasma membrane	IDA	18522992
GO:0086009	Process	Membrane repolarization	IDA	19542013
GO:1901018	Process	Positive regulation of potassium ion transmembrane transporter activity	IDA	10636900
GO:1903278	Process	Positive regulation of sodium ion export across plasma membrane	IDA	10636900
GO:1903288	Process	Positive regulation of potassium ion import across plasma membrane	IDA	10636900
GO:1903779	Process	Regulation of cardiac conduction	TAS
GO:1990573	Process	Potassium ion import across plasma membrane	IBA	21873635
GO:1990573	Process	Potassium ion import across plasma membrane	IDA	10636900, 19542013

MIM	HGNC	e!Ensembl
601867	806	ENSG00000069849

Protein

UniProt ID

P54709

Protein name

Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298)

Protein function

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00287	Na_K-ATPase	6 → 273	Sodium / potassium ATPase beta chain	Family

Sequence

MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWV
MLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLE
EQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIG
LKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPN
NTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA

Sequence length

279

Interactions

View interactions

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