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ADRB1 (adrenoceptor beta 1)
Gene
Gene SNPs Other IDs
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
153
Gene nameGene Name - the full gene name approved by the HGNC.
Adrenoceptor beta 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ADRB1
SynonymsGene synonyms aliases
ADRB1R, B1AR, BETA1AR, FNSS2, RHR
ChromosomeChromosome number
10
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q25.3
SummarySummary of gene provided in NCBI Entrez Gene.
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter
SNPsSNP information provided by dbSNP.
Gene SNPs Other IDs
SNP ID Visualize variation Clinical significance Consequence
rs1801253 G>A,C Drug-response Coding sequence variant, missense variant
miRNAmiRNA information provided by mirtarbase database.
Gene SNPs Other IDs
miRTarBase ID miRNA Experiments Reference
MIRT717492 hsa-miR-188-5p HITS-CLIP 19536157
MIRT717491 hsa-miR-6866-3p HITS-CLIP 19536157
MIRT717490 hsa-miR-186-3p HITS-CLIP 19536157
MIRT717489 hsa-miR-3124-3p HITS-CLIP 19536157
MIRT717488 hsa-miR-2113 HITS-CLIP 19536157
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene SNPs Other IDs
GO ID Ontology Definition Evidence Reference
GO:0001996 Process Positive regulation of heart rate by epinephrine-norepinephrine IBA 21873635
GO:0001997 Process Positive regulation of the force of heart contraction by epinephrine-norepinephrine IEA
GO:0002024 Process Diet induced thermogenesis IEA
GO:0002025 Process Norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure IBA 21873635
GO:0004930 Function G protein-coupled receptor activity IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene SNPs Other IDs
MIM
HGNC
e!Ensembl
Protein
Gene SNPs Other IDs
UniProt ID P08588
Protein name Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor)
Protein function Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G
PDB 2LSQ , 7BTS , 7BU6 , 7BU7 , 7BVQ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1
75 → 377
7 transmembrane receptor (rhodopsin family)
 Family
Sequence
Sequence length 477
Interactions View interactions

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