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ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
128
Gene nameGene Name - the full gene name approved by the HGNC.
Alcohol dehydrogenase 5 (class III), chi polypeptide
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ADH5
SynonymsGene synonyms aliases
ADH-3, ADHX, AMEDS, BMFS7, FALDH, FDH, GSH-FDH, GSNOR, HEL-S-60p
ChromosomeChromosome number
4
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q23
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein for
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020534 hsa-miR-155-5p Proteomics 18668040
MIRT044260 hsa-miR-106b-5p CLASH 23622248
MIRT695423 hsa-miR-3927-3p HITS-CLIP 23313552
MIRT695422 hsa-miR-6831-5p HITS-CLIP 23313552
MIRT695421 hsa-miR-1247-3p HITS-CLIP 23313552
Transcription factors
Transcription factor Regulation Reference
RARB Unknown 1996113
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001523 Process Retinoid metabolic process IEA
GO:0003016 Process Respiratory system process IEA
GO:0004024 Function Alcohol dehydrogenase activity, zinc-dependent IBA 21873635
GO:0005504 Function Fatty acid binding IDA 8460164
GO:0005739 Component Mitochondrion IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P11766
Protein name Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase class chi chain) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutat
Protein function Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (PubMed:8460164). Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarac
PDB 1M6H , 1M6W , 1MA0 , 1MC5 , 1MP0 , 1TEH , 2FZE , 2FZW , 3QJ5 , 8GV3
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08240 ADH_N
32 160
Alcohol dehydrogenase GroES-like domain
Domain
PF00107 ADH_zinc_N
202 334
Zinc-binding dehydrogenase
Family
Sequence
Sequence length 374
Interactions View interactions

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