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ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide)
Gene
Gene SNPs Transcription factors Other IDs
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
124
Gene nameGene Name - the full gene name approved by the HGNC.
Alcohol dehydrogenase 1A (class I), alpha polypeptide
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
ADH1A
SynonymsGene synonyms aliases
ADH1
ChromosomeChromosome number
4
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q23
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze
miRNAmiRNA information provided by mirtarbase database.
Gene SNPs Transcription factors Other IDs
miRTarBase ID miRNA Experiments Reference
MIRT021722 hsa-miR-132-3p Microarray 17612493
MIRT768615 hsa-miR-4468 CLIP-seq
MIRT768616 hsa-miR-4677-3p CLIP-seq
MIRT768617 hsa-miR-4679 CLIP-seq
Transcription factors
Gene SNPs Transcription factors Other IDs
Transcription factor Regulation Reference
GATA2 Activation 16153155
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene SNPs Transcription factors Other IDs
GO ID Ontology Definition Evidence Reference
GO:0004024 Function Alcohol dehydrogenase activity, zinc-dependent IBA 21873635
GO:0004024 Function Alcohol dehydrogenase activity, zinc-dependent IDA 9982
GO:0004745 Function Retinol dehydrogenase activity IBA 21873635
GO:0005515 Function Protein binding IPI 16153155
GO:0005654 Component Nucleoplasm IDA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene SNPs Transcription factors Other IDs
MIM
HGNC
e!Ensembl
Protein
Gene SNPs Transcription factors Other IDs
UniProt ID P07327
Protein name Alcohol dehydrogenase 1A (EC 1.1.1.1) (Alcohol dehydrogenase subunit alpha)
Protein function Alcohol dehydrogenase (PubMed:2738060). Oxidizes primary as well as secondary alcohols. Ethanol is a very poor substrate (PubMed:2738060).
PDB 1HSO , 1U3T
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08240 ADH_N
34 → 161
Alcohol dehydrogenase GroES-like domain
 Domain
PF00107 ADH_zinc_N
203 → 339
Zinc-binding dehydrogenase
 Family
Sequence
Sequence length 375
Interactions View interactions

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