Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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112 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Adenylate cyclase 6 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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ADCY6 |
SynonymsGene synonyms aliases
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AC6, LCCS8 |
ChromosomeChromosome number
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12 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q13.12 |
SummarySummary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
O43306 |
Protein name |
Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase) |
Protein function |
Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:17110384, PubMed:17916776). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth musc |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF16214 |
AC_N |
11 → 368 |
Adenylyl cyclase N-terminal extracellular and transmembrane region |
Family |
PF00211 |
Guanylate_cyc |
370 → 553 |
Adenylate and Guanylate cyclase catalytic domain |
Domain |
PF06327 |
DUF1053 |
580 → 669 |
Domain of Unknown Function (DUF1053) |
Family |
PF00211 |
Guanylate_cyc |
970 → 1164 |
Adenylate and Guanylate cyclase catalytic domain |
Domain |
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Sequence |
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Sequence length |
1168 |
Interactions |
View interactions |