Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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2181 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Acyl-CoA synthetase long chain family member 3 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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ACSL3 |
SynonymsGene synonyms aliases
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ACS3, FACL3, LACS 3, LACS3, PRO2194 |
ChromosomeChromosome number
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2 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q36.1 |
SummarySummary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
O95573 |
Protein name |
Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2) |
Protein function |
Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:22633490). Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholi |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00501 |
AMP-binding |
113 → 587 |
AMP-binding enzyme |
Family |
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Sequence |
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Sequence length |
720 |
Interactions |
View interactions |