Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10057 |
Gene nameGene Name - the full gene name approved by the HGNC.
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ATP binding cassette subfamily C member 5 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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ABCC5 |
SynonymsGene synonyms aliases
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ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 |
ChromosomeChromosome number
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3 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q27.1 |
SummarySummary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, M |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
O15440 |
Protein name |
ATP-binding cassette sub-family C member 5 (EC 7.6.2.-) (EC 7.6.2.2) (Multi-specific organic anion transporter C) (MOAT-C) (Multidrug resistance-associated protein 5) (SMRP) (pABC11) |
Protein function |
ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Mediates ATP-dependent transport of endogenous metabolites such as cAMP and cGMP, folic acid and N-lac |
PDB |
8KCI
,
8WI2
,
8WI3
,
8WI4
,
8WI5
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00664 |
ABC_membrane |
179 → 447 |
ABC transporter transmembrane region |
Family |
PF00005 |
ABC_tran |
578 → 713 |
ABC transporter |
Domain |
PF00664 |
ABC_membrane |
859 → 1143 |
ABC transporter transmembrane region |
Family |
PF00005 |
ABC_tran |
1210 → 1358 |
ABC transporter |
Domain |
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Sequence |
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Sequence length |
1437 |
Interactions |
View interactions |